Nov
11
2023

New Treatment against Advanced Bladder Cancer

At a Cancer congress in Madrid, Spain a new treatment against advanced bladder cancer was discussed at this year’s European Society for Medical Oncology Congress. The standard treatment for advanced bladder cancer is gemcitabine in combination with cisplatin or carboplatin. According to CNN the median survival with the standard chemotherapy is 16.1 months. In contrast, treatment with the new intravenous antibody drug enfortumab vedotin in combination with intravenous pembrolizumab resulted in longer survival. The combination yielded a survival of 31.5 months for advanced bladder cancer patients. This new immunotherapy method resulted in a 96% longer survival. The safety profile of the two approaches were similar. 55.9% of patients taking the combination immune therapy developed skin rashes or hyperglycemia, while 69.5% of those taking platinum chemotherapy developed this.

Other new findings about advanced bladder cancer treatment

Dr. Thomas Powles is a professor of urology cancer at the University of London and director of the Barts Cancer Centre in the United Kingdom. He said:” The problem with chemotherapy is although it works quite well initially, resistance occurs quickly, and the median survival for metastatic bladder cancer has been about a year. What this study showed is, we did a big, randomized Phase 3 study where we compared a new treatment — two new drugs — with standard chemotherapy,” Powles said. “And in this randomized trial, when you gave those two drugs together, you reduced the risk of death for this cancer by over 50%. So, you’ve doubled survival, with patients living twice as long, and we’ve got long-term durable remission.”

Erdafitinib study

A second study from the New England Journal of Medicine used erdafitinib in comparison to standard chemotherapy. Erdafitinib is a small molecule inhibitor of fibroblast growth factor receptor and is effective in the treatment of cancer. This study compared 136 patients on erdafitinib with 130 patients on chemotherapy. Patients treated with standard chemotherapy had a median overall survival of 7.8 months. This compares to 12.1 median survival for the erdafitinib group. Erdafitinib, a kinase inhibitor drug, is slowing the spread of cancer cells.

Side effects that led to death were less common with erdafitinib than with chemotherapy. Only 0.7% of erdafitinib patients had serious side effects versus 5.4% of chemotherapy patients.

Nivolumab study

Another clinical trial was recently published in the New England Journal of Medicine.

Nivolumab is an immune checkpoint inhibitor that was originally developed for treatment of intractable melanoma. However, subsequently it was found to be active also against lung cancer, kidney cancer and bladder cancer. In the clinical study mentioned above 304 patients with intractable bladder cancer were treated with standard chemotherapy alone. They were compared to 304 patients on standard chemotherapy plus nivolumab.

The median complete response with the nivolumab-combination therapy was 37.1 months. In contrast, with gemcitabine–cisplatin alone it was only 13.2 months. Side effects of the two treatments were about similar. The authors concluded that treatment with the immune checkpoint inhibitor, nivolumab plus standard chemotherapy with gemcitabine–cisplatin resulted in better survivals than treatment with gemcitabine–cisplatin alone.

Discussion

Immunomodulation is one of the newest approaches to cancer treatment. But at the Hope 4 Cancer Clinic immunomodulation is only one aspect of a comprehensive approach to cancer treatment.They mention that they restore the microbiome in the gut. Great detail is spent to a full spectrum nutrition. Detoxification and non-toxic cancer therapies are employed. Oxygenation helps to restore the acid/base balance. Immunomodulation with the newer agents mentioned above helps as well to combat cancer. Low-dose laser photodynamic therapy with various light frequencies helps to destroy cancer cells as well. These lasers activate a variety of sensitizers, which are taken up by cancer cells and lead to their destruction. Finally, the cancer patients are taught how to achieve spiritual and emotional well-being. The Hope 4 Cancer Clinic demonstrates that treatment with immunomodulation is best combined with other treatment modalities to improve patient survival.

New Treatment against Advanced Bladder Cancer

New Treatment against Advanced Bladder Cancer

Conclusion

Physicians used three different immune therapies to treat advanced bladder cancer. Erdafitinib vedotin, a kinase inhibitor drug, in combination with intravenous pembrolizumab resulted in a survival of 31.5 months for advanced bladder cancer patients versus 16.1 months with standard chemotherapy. Another clinical trial showed that patients on standard chemotherapy had a median overall survival of only 7.8 months for advanced bladder cancer. This compares to 12.1 months median survival for the erdafitinib group. Finally, nivolumab, an immune checkpoint inhibitor was combined with standard chemotherapy. When end stage bladder cancer patients were treated with this combination, they survived 37.1 months. In comparison, the control group with chemotherapy alone (gemcitabine–cisplatin) survived only 13.2 months. There is definitely better survival of patients when immunomodulation is used. The hope is that future immunomodulators will have a stronger effect against cancer with less side effects.

Feb
23
2019

Combatting Hair Loss

Dr. Alan Bauman gave a talk about combatting hair loss. This talk was part of the 26th Anti-Aging Conference of the American Academy of Anti-Aging Medicine in Las Vegas from December 13 to15, 2018.

Dr. Bauman is the owner of many hair loss clinics around the US. Dr. Bauman said that the baldness gene is present in 4 out of 7 men. The gene codes for male alopecia, which means hair loss. We are all familiar with it. First it causes only a receding hairline in the front. Later it causes thin hair and baldness at the crown. But in later years this gene causes baldness in males. One of the metabolites of testosterone, DHT (dihydrotestosterone) causes hair follicles to miniaturize. The result is that hair is no longer covering the scalp skin as much as it used to.

Mild hair loss

In the case of mild hair loss local application of 5% Minoxidil will often make a big difference. The physician will want to order a testosterone blood level. It this is low, replacement with testosterone will restore his libido, normalize his erectile dysfunction and give him more energy. Often his hair growth will also recover to a certain extent. Together with Minoxidil 5% he may be doing well for 5 or 10 years.

But eventually the persistence of DHT as the end metabolic product of testosterone gets the upper hand and causes more hair loss.

Low-level laser therapy is another method how to re-stimulate the atrophied hair follicles to grow to full hair again. Dr. Bauman showed amazing before and after images that documented vigorous new hair growth with low-level laser therapy.

Moderate hair loss

Those men who have the baldness gene will experience more severe hair loss by the age of 30 to 40. More effective methods are necessary to help him. Oral finasteride is one medication the doctor can prescribe. But one of the side effects can be a decrease in libido, which many men will not like. But the patient can apply finasteride 0.25% topical to the hair. This reduces systemic side effects, but helps the hair to grow. Minoxidil 5% can be combined with topical finasteride.

Platelet rich plasma

One step further is the use of platelet rich plasma. Blood is collected from the patient. A dual-spin procedure produces platelet rich plasma. This was tested in the laboratory and showed about 7-fold the amount of lymphocytes, 3-times the amount of monocytes and 6.3-fold more platelets than whole blood. This PRP preparation is injected into the areas where hair growth is missing. If there are still atrophied hair follicles present in the scalp, lush new hair growth will develop following PRP injections. The effect of the PRP injections can also increase by additional low-level laser therapy. PRP is especially useful for the treatment of alopecia areata, which otherwise would be difficult to treat. To a certain degree PRP injections will also serve a male well that has androgenic hair loss.

Severe hair loss

When a male with the baldness gene enters the late 50’s or 60’s there may no longer be viable atrophied hair follicles present in the bald areas. This is when you have to make a decision whether to shave your whole head and embrace baldness or whether you are using the more expensive hair transplant method. The occipital hair, even in bald people is not responding to DHT. This is why occipital hair is the ideal donator site for a hair transplant. This consists of harvesting DHT-resistant hair follicles from the occipital scalp and transplanting them into the areas that are in need to be cosmetically improved. It is a time consuming procedure, transplanting one follicle at a time.

Hair transplant

The technique is either manual transplantation or robotic-assisted hair transplant surgery. As only parts of the occipital hair follicles are useful material, there is no scar or baldness from the surgery. In 7 days the occipital area has healed over. A man may require 3 or 4 hair transplants in a lifetime to cover up areas of the scalp that were balding because of the baldness gene. But the end result is natural looking hair that now is resistant to DHT as it was transplanted from the occipital scalp. A total of four hair transplants are possible without denuding the scalp region. Dr. Bauman showed many before and after photos of men who had hair transplants.

Combatting Hair Loss

Combatting Hair Loss

Conclusion

Hair loss is common, perhaps more so in men than in women. However, in both cases a lot of therapeutic approaches are possible. Milder hair loss responds to treatment with Minoxidil 5%. In addition finasteride in a local 0.25% topical application is a choice. When hair loss is more severe, PRP (platelet rich plasma) injections into the scalp area are a possibility, but only where viable, but atrophied hair follicles are not growing enough hair. This may give a very acceptable result.

But the aging male who has genetic baldness working against him needs to consider a hair transplant with DHT resistant hair follicles from the occipital scalp into the bald areas.

The beauty is that there is a solution for every one. Due to extensive research of the various methods you can trust that they will give you the results you want.

Jun
23
2018

Low-Dose Laser Activated Stem Cell Therapy

Low-dose laser activated stem cell therapy is a treatment solution for those with degenerative joint disease. Degenerative joint disease or osteoarthritis typically affects the major joints like the knees or the hips. Low-dose laser can activate stem cells. In doing so this therapy can also offer a solution for those with chronic back pain due to degenerative changes in the discs or facet joints.

Osteoarthritis in the spine

Last year my family doctor diagnosed osteoarthritic changes in the discs and facet joints of my lower back. I visited Dr. Weber in Germany and he treated me with low-dose laser activated stem cell therapy in November 2017. A prior blog explained the details of this treatment.

New symptoms of back pain in the thoracic spine

During the spring and summer of 2018 I noted that there was some residual back pain in my dorsal spine (also known as thoracic spine). This was just above the previously treated back pain, which had been fine since November 2017. My family doctor arranged for an MRI scan of the thoracic spine confirming moderately severe degenerative changes in the discs and facet joints of the lower thoracic spine. This was not really a surprise because of a family history of these kinds of degenerative problems on my mother’s side. I thought that I should go back to Dr. Weber in Germany. He had given me relief from my back pain in the lumbar spine with low-dose laser activated stem cell therapy.

Additional left knee pain

I also had developed pain in my left knee, which got worse from kneeling or walking on uneven ground. There was definitive grinding in my left knee when my physician palpated the knee joint while moving the lower leg. My right knee did not have any pain, and there was no grinding in it.

First day of my treatment in May 2018

I will not explain in detail the process of the treatments. You can read about it in my prior blog.

However, I will describe the overall treatment schedule.

1. General assessment by Dr. Weber

Before any treatment Dr. Weber went over the history of my thoracic spine pain and the pain in my left knee. He projected the result of the MRI scan of my thoracic spine onto a large TV screen. I could see the degenerative changes of many discs and facet joints on both sides in the lower 6 levels of my thoracic spine.

2. Liposuction to remove fat as a mesenchymal cell source

The treatment started with anesthetizing the area where the physician intended to harvest fat from my right lower buttock area. Next the fat went into a cell separator to separate stem cells and fat. The fat is not necessary for the procedure, only the stem cells.

3. Venipuncture to harvest blood for PRP

Blood was drawn from one of my arm veins for preparing PRP (platelet rich plasma). This fraction of the blood is necessary to activate the stem cells from either fat cells or bone marrow.

4. Left knee and lower thoracic spine injections

Dr. Weber used an intraarticular needle to inject a mixture of the fat derived (mesenchymal) stem cells and PRP. After the injection into my left knee, the physician removed the syringe but left the needle in place.

Through the needle the doctor inserted very fine sterile glass fibers for intraarticular laser treatment. This consisted of five laser colors using low-dose laser beams. The colors were yellow, blue, green, infrared and red. The significance of the various colors and how deep they penetrate into tissues was discussed under this blog.

Stem cell therapy of lower thoracic spine

Stem cell therapy of lower thoracic spine

Thoracic spine injection

Next Dr. Weber determined first the depth of the lower thoracic spine. An ultrasound machine showed him that he could not exceed 18 mm in length when injecting needles into my back. This would ensure that he did not puncture my lungs. Dr. Weber explained to me that some people had a 2- or 4-inch subcutaneous fat layer. Dr. Weber used 12 interstitial injection needles to inject 6 levels of my lower thoracic spine (6 on each side). This step is depicted in the image on the left, where my wife took a photo of the low-dose laser treatment after the insertion of the 12 interstitial needles . This was stimulating the injected mesenchymal stem cells.

At the end of the first day I received an infrared light treatment over my thoracic spine for 20 minutes, followed by a treatment in a light therapy bed for 20 minutes. These latter treatments were necessary in addition to the laser treatments to stimulate the stem cell activity further.

Second day of my treatment in May 2018

The second day was only a half-day treatment. Dr. Weber had kept half of the fat-derived stem cells and of the PRP preparation in the fridge overnight.

Another injection of a mixture of fat-derived mesenchymal stem cells and PRP into my left knee followed, as well as an injection along the lower thoracic spine. Essentially, this was a repetition of the treatments of the previous day for both my left knee and the lower thoracic spine. Dr. Weber explained that there is merit in doing it this way. He said it would increase the success rate of the low-dose laser activated stem cell therapy.

The reasons behind low-dose laser activated stem cell therapy

A group of dentists have shown that mesenchymal stem cells from bone marrow, dental pulp, periodontal ligament or adipose tissue showed stimulation by low-dose laser therapy.

Detailed research from Japan has shown that low-dose laser therapy releases various growth factors from mesenchymal stem cells, from osteoblast cells and other cells including skin cells. This can promote wound healing and helps stem cells to build up cartilage in joints.

Bone marrow stem cell stimulation

The stimulation of bone marrow by low dose laser therapy also releases bone marrow derived stem cells into the blood. This way these stem cells can contribute to the healing process in joints. Dr. Weber used this method to stimulate release of bone marrow-derived stem cells into my system. He punctured my pelvic bone with an interstitial needle. Subsequently he introduced glass fibers through the interstitial needle into the bone marrow space. Five colors of laser, namely yellow, blue, green, infrared and red were used to stimulate the stem cells of my bone marrow. Dr. Weber explained that low-dose laser activated bone marrow stem cells can easily leave the bone marrow and travel via the circulatory system. This is how they reach the area where they are needed.

History of stem cell therapy

Dr. Michael Weber published a book entitled “Medical low-level-laser therapy, foundations and clinical applications”, 2nd edition, June 2015. On page 541 he explains the beginning of stem cell research by Dr. James Till and Dr. Ernest McCulloch in Toronto/Ont in 1961. He explained further how activation of mesenchymal stem cells by low-dose laser light improved cell viability and cell growth. Barboza et al. also researched these topics.

How do I feel about low-dose laser activated stem cell therapy?

Within only 1 ½ weeks I noticed that my thoracic spine pain disappeared. My left knee pain disappeared within 2 weeks. I am aware that there is a consolidation phase of possibly 3 to 6 months which is necessary to build up the full amount of cartilage. But it is the relief of pain that I was hoping for. Rather than treating my osteoarthritis with pain pills and wait until a total knee replacement, I have now a second chance to regain full mobility without pain. Now I feel more confident about aging without the “usual aches and pains” and staying free from disease.

Low-Dose Laser Activated Stem Cell Therapy

Low-Dose Laser Activated Stem Cell Therapy

Conclusion

I described how Dr. Weber treated my mid back and left knee with mesenchymal stem cells. These were activated by platelet rich plasma (PRP) and low-dose laser therapy. Stem cells from fatty tissue are called mesenchymal stem cells. They are useful for building up lost hyaline cartilage, the coating of bone in joints. With degenerative arthritis, also called osteoarthritis, this layer is getting thinner, sometimes to the point where bone rubs on bone. But stem cell treatment with mesenchymal stem cells can rebuild hyaline cartilage. This is part of regenerative medicine where the body’s own stem cells can help to cure disease.

My family has a strong history of osteoarthritis. But fortunately I seem to respond to regenerative medicine using low-dose laser activated stem cell therapy.

Feb
18
2018

Causes Of Back Pain And Their Treatment

There are many possible causes of back pain and their treatment is described in this blog. I have listed the 10 most common causes of back pain below. I also added brief therapeutic suggestions.

Facet joint disease (lower back strain)

When there is a misalignment of the facet joints, the joint capsules of these small joints are pulled, which can cause severe back pain. Chiropractic or physiotherapy treatments initially followed by active exercises will help (facet joint pain).

Degenerative disc and facet joint disease

Degenerative changes of the disc material between vertebral bodies and osteoarthritis of the facet joints can cause back pain. This is due to irritation of the nerve roots. Anti-inflammatory medication and physiotherapy treatments often help; swimming will be beneficial as well. End stage intractable disease, if confined to one or two levels, may respond to fusion surgery by a spinal surgeon. While you research the surgical option, I suggest you investigate about the possibility of stem cell therapy with PRP (platelet rich plasma). This is less invasive and will likely heal better than conventional surgery.

Spondyloarthropathies

This is a family of chronic inflammatory joint diseases of the spine . The physician treats the underlying disease and uses anti-inflammatories to control inflammation. Most of all, a person with this condition needs a referral to a rheumatologist for more specific therapy.

Osteoporosis

Osteoporosis is a bone condition that can lead to compression fractures of the spine. These in turn can irritate one of the nerve roots to lea to radiating pain into one or both legs. The physician will treat the underlying hormone disbalance, if present. Regular walking and swimming are used to remobilize. Avoid alcohol, caffeine and stop smoking. Supplements like calcium, bisphosphonates, vitamin D in higher doses and vitamin K2 can help re-calcify the bone.

Scoliosis

Scoliosis is often congenital. This spinal curvature leads to back pain and hurts more the more the spine is curved. Treatment: bracing during growth spurts; good posture; strengthening exercises; in severe cases corrective surgery by a spinal surgeon through the use of Harrington rods.

Spinal stenosis

Spinal stenosis is often the end condition of severe degenerative arthritis of the spine. It is more common in the older generation. As this link explains, there is a narrowing of the channel through which the spinal cord travels. In the past decompression surgery for severe cases was the only means to free spinal cord and nerve roots. In the last few years stem cell therapy is a new addition as an alternative to orthopedic surgery. The advantage of stem cell therapy is that there is no scarring following the procedure and the stem cells function like a biological knife from inside.

 Posttraumatic fibromyalgia

Some people develop lower back pain following traumatic injuries. Instead of resolving their muscle sprain, they end up with chronic pain. Often low dose antidepressants and cognitive therapy will help. Mild physical exercises may help to rehabilitate the patient and return to normal muscle mobility. Unconventional therapy like prolotherapy, dry-needling and low-dose laser therapy (Dr. Weber) may be useful.

Disc herniation with or without sciatica

With disc herniation the back pain is intense, which often prompts the orthopedic surgeon to do an early discectomy (back surgery). But long term studies have shown that only in 3% of all acute back pain cases surgery is necessary; many cases heal on their own. In this case the new regenerative medicine approach of stem cell therapy with PRP will give superb clinical results. Stem cells will rebuild the disc and also take care of any arthritis in the small joint along the spine.

Spondylolisthesis and other congenital malformations

There are 4 grades of slipped vertebral body diseases (spondylolisthesis), where grade IV is the most severe case. Grade I to IIIA do not need surgery, stage IIIB and IV need fusion with instrumentation by a spinal surgeon.

Bone metastases

In stage 4 of many cancers metastases travel through the whole body including the skeleton. The underlying cancer needs treatment, often chemotherapy is required. Unfortunately cancers with bone metastases have a very poor prognosis. Here is a link how to manage symptoms of bone metastases.

Causes Of Back Pain And Their Treatment

Causes Of Back Pain And Their Treatment

Conclusion

I have listed the ten most common ones of back pain. For muscle spasms, simple physiotherapy or chiropractic treatment are often very helpful. Early degenerative changes in joints and discs will often respond to anti-inflammatory medication. But anti inflammatory drugs can be hard on your liver and your kidneys. If your back pain is getting more chronic, your doctor may want to arrange for an MRI scan of the area that causes pain. If this shows degenerative change in the discs and facet joints it is time to contact a regenerative medicine clinic. They specialize in stem cell and platelet rich plasma (PRP) treatments. This may be what you need to restore your back to normal. Conventional surgical methods are often the choice, but they are not always successful. Surgery can leave scarring behind, which by itself can give you chronic back pain.

Mar
19
2016

Book Review: “Healing Gone Wrong – Healing Done Right”, By Ray Schilling, MD

This book entitled “Healing Gone Wrong – Healing Done Right” (Amazon, March 18, 2016) is dealing with the practice of medicine then and now. Medical errors, false diagnoses and wrong treatments are nothing new in the history of medicine. It happened in the past, and it is happening now. My first book was about anti-aging. The title was “A Survivor’s Guide to Successful Aging” (Amazon 2014).

Book overview

Chapter 1

Here I describe describe that famous people like President Kennedy, Elvis Presley, Churchill, Beethoven or more recently Michael Jackson have something in common: all of them suffered the consequences of blatant medical mistakes. In Beethoven’s time lead containing salves to plug the drainage holes from removing fluid from his abdomen caused lead poisoning. In this chapter I review also how doctors treated the illnesses of the above-mentioned celebrities, but then ask the question: “What better treatments have offered to prevent some of the disastrous treatment outcomes?”

Chapter 2

Modern drugs seem to come and go. We learn that twenty-first century medications that are supposed to be the latest therapeutic agents are having their potentially deadly consequences too: COX-2 inhibitors, the second generation arthritis drugs cause strokes and heart attacks! Your doctor may still prescribe some of these dangerous drugs for arthritis now.

Chapter 3

This chapter deals with the fact that medical treatments for people’s diseases may be inappropriate when the doctor treats only symptoms, but the doctor does nothing about the causes of their illnesses. This is a scary thought.

Chapter 4

What does it take to prevent these poor health outcomes, so that we will be able to prevent any disastrous outcomes pertaining to our own health care in the present and future? As we will see, the problem today is still the same as it was in the past, namely that many physicians still like to treat symptoms instead of the underlying cause of an illness. Big Pharma has the seducing concept of a pill for every ill, but it is not always in your best interest, when these medications have a slew of side effects. “Gastric reflux” means a mouthful of stomach acid. Big Pharma simply offers the patient with the symptom of gastric reflux a multitude of medications to suppress this symptom. But it is more important to dig deeper to find the reason for the illness and treat the underlying cause.

Chapter 5

We all need our brain to function. This chapter concentrates on the brain and how we can keep our brains functioning optimally until a ripe old age. This review spans from prevention of head concussions to avoiding type 3 diabetes (insulin sensitivity from overconsumption of sugar). It manifests itself in Alzheimer’s disease. It is a form of diabetes of the brain that leads to deposits of a gooey substance. Prevention of this condition is also reviewed .

Chapter 6

This chapter reviews what we now know about how to keep a healthy heart. Certain ingredients are necessary such as regular exercise, a healthy Mediterranean diet, supplements etc. The good part is that what is good for the heart is also good for the brain. You are preventing two problems (brain and heart disease) at the same time.

Chapter 7

What should we eat? And why does healthy food intake matter? Without the right ingredients of our body fuel, the body machinery will not work properly. The Mediterranean diet is an anti-inflammatory diet that is particularly useful.

Chapter 8

We need healthy limbs, bones and joints. We are meant to stay active in our eighties and nineties and beyond. No osteoporosis, no joint replacements, no balance problems that result in falls! Learn about how to deal with problems like these in this chapter.

Chapter 9

This chapter deals with detoxification. What do we do as we are confronted with pollution, with radiation in the environment and poisons in our daily food? A combination of organic foods, intravenous chelation treatments and taking supplements can help us in that regard.

Chapter 10

I am dealing here about reducing the impact of cancer in our lives. A lot of facts have come out in the past 10 years telling us that reduction of sugar and starchy food intake reduces cancer. Curcumin, resveratrol and vitamin D3 supplements also reduce cancer rates as does exercise and stress management. All of this is reviewed here.

Chapter 11

This chapter tells you all you need to know about your hormone status. Women need to avoid estrogen dominance; both sexes need to replace the hormones that are missing. By paying attention to your hormonal status and replacing the missing natural hormones with bioidentical ones, most people can add 10 to 15 years of useful, active life!

Chapter 12

Here you will learn more about anti-aging. You will learn about the importance to keep your mitochondrial DNA healthy. Apart from that there are ways how to keep your telomeres longer; certain supplements that are reviewed will help. Also your lifestyle does make a big difference in how old you can turn.

Chapter 13

This chapter investigates the limits of supplements. Many supplements are useful, but you do not want to overdo it and get into toxic levels. More is not necessarily better!

Chapter 14

Here is a review of an alternative approach to treating ADHD. Attention deficit and hyperactivity disorder has been over diagnosed, has been neglected and has been over treated with dangerous drugs. An alternative treatment plan is discussed, which includes a combination of therapeutic steps.

Chapter 15

This gives you a brief summary of the book.

Kirkus Review

Kirkus Reviews reviewed the book on March 17, 2016: “A retired physician details how various preventative measures can fend off disease and disability in this consumer health guide. Schilling (A Survivor’s Guide to Successful Aging, 2014) had a family medicine practice in Canada for many years before retiring. Although Schilling ventures into some controversial territory in his latest book, it’s generally an engaging, helpful synthesis of ideas that draws on reputable research from the Mayo Clinic and other sources. Overall, it serves as an intensely detailed wake-up call to the importance of preventative health. He largely brings an accessible and even-tempered tone to his narrative, warning readers, for example, that preventative health measures can only aid in “a delay of aging, not ‘eternal living.’ ” A thought-provoking, impassioned plea to be proactive about one’s health.”

Healing Gone Wrong – Healing Done Right

Healing Gone Wrong – Healing Done Right

Conclusion

In this book it becomes evident that it is better to prevent an illness whenever possible rather than to wait for illness to set in and cause disabilities or death. You heard this before: “Prevention is better than a cure” or “an ounce of prevention is better than a pound of cure”. I will give an explanation, based on scientific data that there is indeed evidence to support these notions on a cellular level.

Mitochondria, the energy packages within our cells

The mitochondria, the energy packages within our cells, are the driving force that keep people vibrantly healthy well into their nineties. All this can only happen when the mitochondria function properly. If toxins poison the mitochondria and as a result they malfunction, we are not looking at a person with vibrant health. Instead sixty or seventy year-olds may use a wheelchair. If you want a life without disabilities, a life without major illnesses and enjoy good health to a ripe old age, you are reading the right book.

The book is written in American English.

Available in the US: http://www.amazon.com/gp/product/1523700904

In Canada: https://www.amazon.ca/Healing-Gone-Wrong-Done-Right/dp/1523700904/  

In other countries the book is available through the local Amazon websites.

Apr
25
2015

Rejuvenate With Stem Cells

We all age; but can we rejuvenate with stem cells? There is a limit to detoxification, to eating organic food, to exercising, to the effects of vitamins and supplements and even to the effect of bioidentical hormone replacements. The limit comes from our telomeres and from stem cells that get depleted in our body as we age. Some researchers report that in regions where we suffer from a disease stem cells are even more depleted than in the rest of the body.

We do not have all the answers yet. We would like to know why our stem cells in the fatty tissue or in the bone marrow do not migrate on their own into an aching back or a sore shoulder. There are all the aches and pains associated with old age. So, why do our own stem cells not help us? They seem to be locked away in fatty tissue and in bone marrow.

At the 22nd Annual World Congress on Anti-Aging Medicine in Las Vegas (Dec. 10-14, 2014) I learnt that there is a group of stem cell experts in California with affiliates all over the US. They simply take stem cells from the fatty tissue and sometimes also from the bone marrow, isolate the stem cells through a stem cell separator and infuse the stem cell rich fraction (minus fatty and connective tissue) in a bit of saline solution back into the vein of the patient. When the stem cells are in the blood stream, they get activated by the growth factors that are present in blood and can now find where they are needed and start the healing process.

Studies have shown that when stem cells are in circulation in the blood, they are very sensitive to signals from tissues that indicate that there is an inflammatory process. This is why stem cells will repair arthritic changes. The can repair a torn meniscus, a rotator cuff tear in the shoulder or repair a weak immune system. The interesting observation is that stem cells from fatty tissue, also termed mesenchymal stem cells, are pluripotent. This means they can develop into cartilage building cells (chondrocytes) and build up cartilage; this is badly needed in a person with severe osteoarthritis. But stem cells are flexible: they can turn into meniscus cells in a knee with a torn meniscus. They also can repair the damage and relief the patient of the chronic pain. In a shoulder with a rotator cuff tear they can turn into a tough ligamentous material mending the tear.

Some data even indicates that circulating stem cells can repair vital organs like the brain, heart, liver, kidneys and bone marrow; these latter observations were mostly done in animal experiments, but human data is starting to be published in the medical literature.

So, let’s examine what has been found useful with regard to stem cells that are taken from your fatty tissue or your bone marrow and injected into one of your veins.

Here is a website from Arizona that I am only showing as a typical example (I have no conflict of interest and no commercial connections to this group) of what I described above.

With websites like this it is also important to read the disclaimer: “Even though our treatments are done using autologous cells, our Stem Cell Therapies are not approved by the FDA. Stem Cell Treatments are not a cure for any condition, disease or injury, nor a substitute for proper medical diagnosis and care…” Another website from La Quinta, CA describes the use of mesenchymal stem cells for regenerative therapies.

Stem cell treatments are in flux. There is a large body of knowledge that has accumulated showing that with proper technique and aseptic conditions it is a safe procedure. The FBA has been watching this. There are publications regarding the safety of procedures with adipose mesenchymal stem cells; here is one example.

The next step is to show in clinical trials that a certain procedure with stem cells is effective in treating a certain condition.

Below I did a literature review, which are only a few examples, but does not claim to be complete; it highlights some of the problems with stem cell treatments.

Stroke treatment with intravenous administration of bone marrow mononuclear stem cells

This study from India showed no statistical difference of stroke patients treated intravenously with bone marrow derived mononuclear stem cells (the experimental group) and the control group that did not receive such treatment. The investigators examined both groups with functional brain tests and performed PET scans to look at the healing of the brain lesions. Unfortunately the tests showed no statistical difference, but did show that the stem cell procedures were safe. It may be that the wrong stem cells were used (mononuclear bone marrow stem cells) when adipose derived mesenchymal stem cells may have done better. In stark contrast to the study from India is the stem cell treatment for a severe stroke in the former hockey player, Gordie Howe that has gone through the media recently. His procedure was done in Mexico. The stem cells were administered via a lumbar puncture approach as well as intravenously. As you can see from this case, stem cell treatment is even possible in patients who are in their mid 80’s with impressive results.

Parkinson’s disease

Here is a feasibility study from March 2014. A 71-year-old Asian man with progressive supranuclear palsy, an aggressive form of Parkinson’s disease was treated with adipose tissue-derived mesenchymal stem cells that were administered intravenously and intrathecally (to get stem cells into the cerebrospinal fluid that bathes the brain). A remarkable functional recovery took place.

Possible side-effects

This is a report of pulmonary embolism after administering intravenous adipose tissue-derived stem cell therapy. The blood clots in the lungs were treated with anticoagulant therapy. Repeat CT scans of his lungs showed later that the emboli were dissolved spontaneously. It is not clear whether this was a case where familial clotting problems pre-existed as a relative of this patient experienced a similar occurrence after stem cell therapy as well.

A case of chronic autoimmune thrombocytopenic purpura

A rare form of autoimmune disease exists where the body forms antibodies against platelets that help your blood to clot. Here is a paper from June 2009 that describes how a man with this disease was cured using adipose tissue-derived mesenchymal stem cells that were injected intravenously.

Renal transplant survival in type 1 diabetes patient

This case report from India shows that adipose tissue derived mesenchymal stem cells that were given at the time of a kidney transplant to treat end stage kidney disease. The treatment stabilized the condition of this patient after a kidney transplant. At the same time some of the mesenchymal stem cells differentiated into insulin producing cells, which made it much easier to control this patient’s diabetes. In this case stem cells were providing stability following an organ transplant (kidney) and some stem cells turned into insulin producing pancreatic cells.

Osteonecrosis of hip treated with adipose tissue derived MSC

In this study from South Korea dated January 2012 two cases of osteonecrosis of the hip, where the hipbone died (osteonecrosis) are described. The following stem cell protocol helped: The fraction that contained the stem cells (called stromal vascular fraction) was mixed with platelet rich plasma and hyaluronic acid. Using a long needle this mixture was injected into the affected hip joint. Conventional medicine has nothing to offer except a total hip replacement. But here are two cases that showed complete resolution of their pain, regained hip function completely, and healing could be documented with the help of MRI scans.

Treating heart attack patients with stem cells

Here is a paper from The Netherlands, published in June 2014 that describes the problems with stem cell treatment in humans. It points out that much has been learnt from animal experiments. The problem following a heart attack is that there is a massive inflammatory response in the infarcted heart muscle, which makes it difficult for stem cells to establish themselves in the injured heart muscle. However, stem cells have been shown to prevent the development of cardiomyopathy that follows a massive heart attack and often is the cause of death. More refinements are needed for successful treatments, such as the ideal timing of stem cell injections in relationship to the time of the heart attack, the best treatment approach and what number of stem cells to inject are all questions that still need to be answered.

MS model in mice shows promise with adipose mesenchymal stem cells

Experimental encephalitis in mice is used as a model for MS in humans. It helps to preselect potentially effective treatments for MS in humans. In this 2013 paper from Australia researchers used mesenchymal stem cells from adipose tissue and injected them intravenously. To their surprise the mesenchymal stem cells were able to penetrate the blood/brain barrier and end up in the myelin lesions inside the brain. In contrast, bone marrow derived stem cells were unable to do that. The researchers stated that adipose mesenchymal stem cells should be considered “as a cell therapeutic that may be used to treat MS patients”.

A group from Iran published this paper in February 2015 further emphasizes that mesenchymal stem cells would be a logical way to treat MS in humans.

Immunosenescence

As we get older the immune systems weakens because of a process called immunosenescence.

A research group from Austria published a paper in December 2011 that is typical for the thinking that mesenchymal stem cells from fatty tissue have properties that help the immune system to get stimulated. Based on this human data it should be possible to stimulate the immune system by giving stem cells from the fatty tissue to the same person intravenously. This publication shows that this process, which would benefit people above the age of 50 or 60 when the immune system gets weaker, will indeed stimulate the immune system. However, at this point we do not have the data of large clinical trials where this would have been done with measurements of the immune function before and on several occasions after stem cell injection to get a feeling for how long the effect would last. We also do not know whether this procedure is associated with longevity.

Rejuvenate With Stem Cells

Rejuvenate With Stem Cells

Conclusion

Stem cell therapy is definitely coming and many applications are already established as I discussed in a prior blog. It is only recently that physicians are no longer worried about creating tumors with stem cell transfer. Now we are in a phase where various stem cell transfer methods (intravenous, intrathecal, interstitial) are being tested as a treatment for various illnesses. It looks like stem cells from fatty tissue may soon be used intravenously, but I have not seen any such trials when checked on PubMed. The activation of stem cells by laser light has only been mentioned sparingly in the literature. This combination (laser activated, intravenous mesenchymal injection) has the potential for being useful for a multitude of chronic illnesses like fibromyalgia, MS, generalized arthritis, just to mention a few. Mesenchymal stem cells are anti-inflammatory, and they can mend defects without leaving scars.

Apr
04
2015

Stop Suffering From Arthritis

This article shows you how to stop suffering from arthritis. Arthritis is an illness of the joints, mostly in older people (osteoarthritis or degenerative arthritis). However, a subgroup of younger patients can also develop a severe form of arthritis, called rheumatoid arthritis where autoimmune antibodies play more of a role.

In the 1950’s Dan Dale Alexander wrote a book called “Arthritis and common sense”. The medical establishment did not accept that simple remedy and Dan Dale Alexander was classified as a “quack”. However, Dr. Mirkin describes a study from Berlin that later confirmed that Dan Dale Alexander’s observation was correct: an emulsion made by shaking orange juice with cod liver oil and taken three times per day on an empty stomach would indeed improve osteoarthritis.

Dan Dale Alexander’s emulsion of orange juice and cod liver oil

In 1966, when I was still a medical student, I suggested to my future mother-in-law to give Dan Dale Alexander’s book about arthritis a try. Despite the well-established osteoarthritic condition in her left knee the arthritis vanished within 6 months and stayed controlled. I could not explain to her why this remedy was effective, as researchers had not yet described higher doses of omega-3 fatty acids and higher doses of vitamin C to be of value for arthritis.

This all changed with the advent of orthomolecular medicine (Ref.1). On page 76 of this book Dr. Frederick Klenner describes that ascorbic acid (vitamin C) at mega doses of at least 10,000 mg daily, but better even between 15,000 and 25,000 mg daily does have healing effects for arthritis. He stated further that repair of collagenous tissue (the joint surfaces) would require adequate ascorbic acid. On page 240 of Ref.1 Dr. Abram Hoffer, the founder of modern orthomolecular medicine reviewed the history of the use of vitamins in higher doses, particularly the use of vitamin B3 (niacin). He also mentioned that Dr. William Kaufman had used mega doses of vitamin B3 for arthritis as far back as 1950.

Overview of arthritis

Dr. Hoffer explains in Ref.2 that arthritis belongs into a group of diseases that are related to faulty nutrition, which in turn lead to vitamin and mineral deficiencies and a pandeficiency disease. Other diseases that belong to that group are cardiovascular disease, multiple sclerosis, cancer, diabetes, schizophrenia, mood disorders, alcoholism and autism. Contributing factors can be poor diets with overemphasis on refined and processed foods and consumption of sugar, allergies, diseases of the gastrointestinal tract and viral infections. Arthritis belongs into this group of illnesses as well. Researchers found that niacin, vitamin B6 and zinc were useful to treat arthritis, but other vitamins and minerals are also necessary. Here is a list of what Dr. Hoffer would suggest to use (Ref. 2):

  1. Vitamin B3

Vitamin B3 from 100 mg to several thousand mg three times daily following meals. With niacin there can be skin flushing, which often goes away after the body gets used to the higher doses; but niacinamide could be used instead by those who are bothered by the flushing.

  1. B complex

B complex: this contains each of the major B vitamins including vitamin B6 (pyridoxine). Take 100 mg once per day with a meal. The dose for vitamin B6 is up to 500 mg per day or more.

  1. Vitamin C

The dosage for vitamin C is between 500 mg and several thousand mg three times per day after meals.

  1. Vitamin D3

To get adequate vitamin D3 levels the patient has to take 4000 IU per day in the summer months. In the winter months particularly populations who live far north require 6000 IU per day.

  1. Vitamin B1 (thiamine)

Vitamin B1 (thiamine): alcoholics and very high sugar consumers need thiamine at 100 to 500 mg three times per day.

  1. Folic acid at mega doses

Folic acid at mega doses (prescription needed) works as an antidepressant, which requires 25 to 50 mg. To lower homocysteine levels lower doses of folic acid are sufficient.

  1. Vitamin E

Vitamin E: usually 400 IU to 800 per day. Muscle wasting diseases, Huntington’s disease and amyotrophic lateral sclerosis (ALS) require much higher doses up to 4000 IU per day.

  1. Essential fatty acids (omega-3)

Essential fatty acids (omega-3): It is strongly recommended to use a molecularly distilled product, which is free of mercury and PBC’s at 1000 mg three times daily following meals.

  1. Selenium

Selenium: The required dosage is 200 to 600 micrograms once daily (with any meal). In areas where selenium is deficient, this is particularly important.

  1. Zinc

Zinc: 50 mg of zinc citrate or 220 mg of zinc sulfate once per day with a meal.

  1. Calcium and magnesium

Calcium and magnesium: Dr. Hoffer suggested 1000 mg of calcium with 500 mg of magnesium, although many experts now say that 1000 mg of calcium with 1000 mg of magnesium may be better.

Dr. Hoffer pointed out that this program is compatible with any medication and is non-toxic.

Thoughts on treating arthritis

 

 1. Conventional methods

The conventional approach to treatment of arthritis consists of anti-inflammatory medications like ANSAIDs. Unfortunately they have side effects like causing kidney damage after several years of use. Also, NSAIDs can lead to gastric bleeding from gastric erosions, which may require blood transfusions. Physiotherapy with reactivation and swimming have been found to be useful. Electro acupuncture can help for pain control.

2. Diet changes, multivitamins and minerals

As arthritis occurs mostly in civilized nations, physicians have long suspected dietary factors to be of importance. Dr. Hoffer pointed out that arthritis is a pandeficiency disease meaning that overconsumption of sugar and processed foods has lead to multiple vitamin and mineral deficits that interfere with the cartilage metabolism leading to premature breakdown of cartilage and causing inflammation. It is not good enough to just take the supplements listed above; this needs to be combined with a fundamental change in diet. Cut out sugar and starchy foods. Return to homemade foods. Keep it simple with lots of vegetables, salads and organic meats. Now that you are starting to turn around your metabolism by a sensible diet the supplements listed above have a chance to work.

You will notice that Dan Dale Alexander’s idea of omega-3 fatty acids and vitamin C (from the freshly pressed orange juice) is contained in the list of supplements above. Dr. Klenner’s mega doses of vitamin C are also listed and Dr. Kaufman’s mega doses of vitamin B3 is contained in this list as well.

This list may not have been formally researched with controlled clinical trials, because the food industry and the makers of NSAIDs (Big Pharma) have no interest in this. But thousands of patients have been empirically treated with this regimen and a network of orthomolecular physicians has established that this regimen works to control the inflammation of arthritis and at the same time has no toxic side-effects.

 3. Laser, platelet rich plasma (PRP) and stem cells

Blue and green lasers have anti-inflammatory properties and are suitable for interstitial and intra articular laser treatments of arthritis. Dr. Weber has extensive experience with this treatment modality in Germany. I have discussed this in another blog.

However, prolotherapy, PRP and stem cell treatments are also an option for more severe cases of arthritis, particularly in arthritis of the knees, which can avoid total knee replacement surgery.

Stop Suffering From Arthritis

Stop Suffering From Arthritis

Conclusion

I met Dr. Hoffer in the early 1980’s during a meeting in Vancouver, BC when he wanted to establish a local orthomolecular division for British Columbia. Although I found the ideas fascinating, I felt that the College of Physicians and Surgeons (the regulatory body for physicians in BC) would scrutinize the practice of any orthomolecular member. At that time I would risk losing my license to practice medicine, which I just had received in 1978. So I decided not to join. Interestingly enough later in the 1980’s a member of the orthomolecular society of BC lost his license because of the use of mega doses of intravenous vitamin C. At this time the College considered these infusions useless or hazardous. Nowadays, any naturopathic and orthomolecular physician uses these intravenous vitamin C treatments as standard therapies. It shows how times have changed.

Lifestyle issues important with causation of arthritis

What has not changed is the food industry that undermines our health every day with hidden sugar contained in processed foods. In social functions it is customary to have a drink or two, if not more, which uses up our thiamine faster than we can replace it. Pan deficiency disease is alive and well as it was many years ago. It is in front of our eyes, but can we see it? Depending on what your eating habits are, do you need to make changes in your diet and perhaps take some or all of the ingredients of the multivitamin and mineral list above? Start by adopting a Mediterranean type diet, then add some of the supplements listed above. It is time to take a thorough look at natural treatment modalities against arthritis in the interest of preserving your health!

References

Ref. 1: Andrew W. Saul, Ph.D.: “The Orthomolecular Treatment of Chronic Disease. 65 Experts on Therapeutic and Preventative Nutrition”, Basic Health Publications, Laguna Beach, CA, 2014.

Ref. 2: Chapter in Ref. 1 by Dr. Hoffer: “Pandeficiency Disease”, pages 24-30 (2014).

Feb
14
2015

Laser Therapy Going Beyond Skin Deep

There was an interesting workshop alongside of the A4M conference mid December 2014 organized by Jonathan Schwartz who gave an overview of the use of low-dose laser therapy for various clinical applications. It involved the use of the Dr. Michael Weber low-dose laser machine, which has a lot of versatility.

  1. First there are 5 laser light frequencies in the rainbow colors (infrared, red, yellow, green, blue) and the colors have very special characteristics as will be explained further below.
  2. There are a multitude of applicators like skin acupressure point applicators, a shower for hair loss applications, a head adapter, which looks like a crown. With this device red light will penetrate into the brain through the skull bone. There is also a mouth shower and various lengths needle applicators that can be used to access the body intravenously or interstitially (direct tissue approach). At the center of the equipment is the Weberneedle Compactlaser, which can be attached to the various applicators.

Laser characteristics

The blue laser penetrates about 1 cm (0.39 inch) under the skin, a green laser penetrates only 0.5 cm (0.19 inch); like the blue laser the yellow laser penetrates through the skin with a depth of 1 cm (0.39 inch). The red laser has a penetration depth of 2-3 cm (a bit more or less than 1 inch) and the infrared laser penetrates 5-7 cm (2 to 2 1/2 inches).

In addition the various lasers have different inherent qualities: The red laser is good for tissue regeneration, which lends itself for chronic pain. Green and blue lasers have anti-inflammatory effects, which helps in acute pain. The yellow laser can be used for detoxification, has antidepressant qualities and photosensitizes hypericin, a substance derived from St. John’s wort, which is known to have antidepressant qualities. The various types of laser mentioned can be used interstitially, intravenously and just on the skin surface over acupuncture points. Dr. Weber explained that detailed research has revealed that the low-dose energy beam sends out energy that is taken up by the surrounding tissues and cells. The mitochondria of the cells get activated to produce more ATP, which the cells use to heal themselves.

Meeting in Placentia

Forward to a meeting in Placentia, CA on Feb. 7, 2015 where Dr. Michael Weber and several other speakers gave presentations on the use of the Dr. Weber laser system. A number of local doctors who had an interest in learning more about the low-dose laser system were there as well. It was a daylong mini conference.

Three volunteers were used to demonstrate the use of the system. I was volunteering about a chronic left lower back pain that various chiropractors had problems adjusting in the past year. I have a strong family history of arthritis on my mother’s side and my maternal grandmother’s side as well. The health professionals thought that I likely have developed arthritis in the left sacro-iliac joint. Dr. Weber used the interstitial needle, which is 4 cm (1.57 inches) long. The skin was injected with a local anesthetic first, and then the needle was inserted, which I could hardly feel. Now he injected 5 cc of normal saline. This was used, so that the laser light would spreads more into the surrounding area. Dr. Weber explained that he was very close to the SI joint with the tip of the needle on the left. He attached a blue laser to it for 20 minutes and switched it to a green laser for another 20 minutes.

In the meantime the other two volunteers were treated.

One was a physician in the group who had a chronic planter’s fasciitis. He was treated with an intravenous laser application. First a special butterfly was inserted, through which a sterile laser probe could be threaded and then attached. He received a red laser.

The third volunteer had a chronic right knee problem from congenital Osgood Schlatter disease. In him Dr. Weber used an approach of intraarticular injection and he attached a blue laser for 20 minutes, followed by a yellow laser for another 20 minutes. A physician with a California license supervised all of these procedures.

I woke up the following day with no pain in my left lower back, but at the same time the lesser right lower back pain had also disappeared. I figure that due to the fact that my back mobility is back the untreated right side must have normalized as well. It is now 7 days following the procedure and I still have no back pain. Yesterday I saw my local chiropractor in Southern California and he confirmed that my back was much easier to adjust than the month before (Update April 12, 2015: my lower back is still pain free!).

Normally a case like mine would require 5 to 6 weekly treatments before the problem is resolved. Dr. Weber explained that more complicated problems like fibromyalgia would take 15 to 20 treatments in succession or more. The principal is always that you treat where the symptoms are; in the follow-up visit the healthcare practitioner treats the remaining symptoms until all of the symptoms have resolved.

The intriguing fact is that low-dose laser therapy seems to fit right into gap where conventional medicine has failed.

Clinical cases that respond to laser therapy

Dr. Weber has collected clinical cases that improve with laser treatments, such as diabetes, chronic liver diseases, chronic pain syndromes, rheumatoid arthritis, polyneuropathy, chronic inflammatory disease, cancer (with photodynamic therapy), fibromyalgia, high blood pressure, ringing in the ears (tinnitus), macular degeneration, multiple sclerosis, chronic fatigue syndrome, Lyme disease, allergies and eczema. This, however, is just a partial list.

Photodynamic cancer therapy is made possible by the fact that certain substances have absorption spectra that are activated by different wavelength. This amplifies the effect of the natural substance that is used by several folds. For instance Chlorin E6 absorbs a red laser (around 660 nm). A blue laser activates Curcumin. A yellow laser activates Hypericin. Here is a website that explains the principle of phototherapy.

Various cancers can be treated where conventional medicine has so far failed. Examples are lymph metastases from breast cancer, pancreatic cancer, and bladder cancer. I have blogged regarding a combination treatment for breast cancer before, where phototherapy with lasers and immunostimulation were combined. Esophageal cancer is treated through esophagoscopy combined with a laser that activates curcumin, which had been taken orally well before the procedure. Not all of the cases are successful, but the majority of them are.

Otherwise routine low-dose laser applications are used for tendinitis, tennis elbow, sprains and soft tissue injures.

Laser-Therapy-Going-Beyond-Skin-Deep

Laser-Therapy-Going-Beyond-Skin-Deep

You can combine the laser system with prolotherapy. Prolotherapy is done first by injecting hyperosmolar dextrose solution, which is a strong stimulator of stem cells. Using the same needle, but attaching the Weber low-level laser therapy will activate the stem cells and protect them from dying off.

Conclusion

Low dose laser therapy using the Weber Medical technology is a new treatment modality available to the interested physician. I think that it will cause a revolution within medicine. It is scientifically sound and it fits right into the difficult to treat patients; the patients that otherwise would be unlikely to respond. However, they will respond well to these new treatment modalities. Apart from musculoskeletal problems, various cancers will also respond to this. The Mayo clinic is starting a study on treating cancer using phototherapy and the Dr. Weber low-dose laser system.