May
02
2015

Healthy Olive Oil

In the past it was thought that the monounsaturated fatty acids in olive oil would be the reason why it is protective of the heart. However, newer studies have shown that it is the polyphenols and among these in particular hydroxytyrosol that lower blood pressure and protect you from hardening of the arteries.

In a 2012 study from Spain it was found that mortality from heart attacks was 44% lower than that of a control group who did not incorporate olive oil in their diet.

How polyphenols in olive oil work for you

Only two tablespoons of extra virgin olive oil per day protect you from heart disease. It does so by reducing the total cholesterol level in the blood as well as the LDL cholesterol level. At the same time the more polyphenol is contained in olive oil (such as in extra virgin olive oil), the more HDL your body will produce, which is essential to extract oxidized LDL from arterial plaque. On top of that polyphenol rich olive oil will increase the size of the HDL particles (these larger particles are called HDL2), which are more efficient in extracting oxidized LDL from arterial plaques. A Sept. 2014 study in humans showed that higher polyphenol olive oil as found in extra virgin olive oil caused an increase in the more effective HDL2 particles, which cleans out plaques from arteries more efficiently than the regular, cheaper olive oil.

Endothelial function

The endothelium is the lining of the arteries. Normal endothelial functioning involves widening of the arteries and maintaining its flexibility. The body achieves this through production of a signal molecule, called nitric oxide; the endothelial cells that line our arteries from inside produce it. Exercise increases the production of nitric oxide as well (Ref.1).

In a group of patients with poor endothelial function 2 tablespoons of olive oil (polyphenol rich) per day given over 4 months (the time of the study) showed a significant improvement of endothelial function.

The authors suggested that an enzyme in the endothelial cells, called nitric oxide synthase is being stimulated by components of polyphenol-rich olive oil. This leads to protracted release of nitric oxide, which in turn keeps blood vessels flexible and wide open. Other investigators found that olive oil can influence even a hereditary gene variant of endothelial nitric oxide synthase found in people with a history of premature heart attacks. This high-risk group of people should take extra virgin olive oil regularly to prevent premature heart attacks and strokes.

Endothelial dysfunction occurs when the arteries no longer can deliver adequate amounts of blood to vital organs like the heart or the brain. Endothelial dysfunction is also present in patients with type 2 diabetes, obesity, high blood pressure and metabolic syndrome. Introducing extra virgin olive oil in the diet of these patients will help restore their endothelial function.

Lowering blood pressure

In a study on 23 hypertensive patients it was shown as far back as in 2000 that extra virgin olive oil over 6 months allowed physicians to reduce high blood pressure medications by 48%. When the study was crossed over, the reverse was the case for the control group on sunflower oil that had no such effect before.

Based on what was said about endothelial function above, it is easy to understand that the polyphenols of olive oil released nitric oxide, which is known to lower blood pressure. This is an important finding as high blood pressure is a known risk factor for the development of hardening of the coronary arteries leading to heart attacks, congestive heart failure, but also stroke. Regular intake of 2 tablespoons of extra virgin olive oil often will reverse high blood pressure and restore normal endothelial function.

Preventing heart attacks and strokes

In April of 2013 The New England Journal of Medicine published a Spanish diet study that showed that a participants on a Mediterranean diet with olive oil or nuts had 30% less heart attacks over 5 years than people on a low fat control diet. Other studies have also shown that olive oil and omega-3 fatty acids play a big role in preventing heart attacks and strokes. We also know that regular exercise reduces the risk further; so does keeping your body mass index below 25.0. Extra virgin olive oil is part of the protection from heart attacks and strokes, but it did not show protection against cancer.

Healthy Olive Oil

Healthy Olive Oil

Conclusion

It is a simple fact that incorporating 2 tablespoons of virgin olive oil in your daily food intake will definitely have all of the beneficial effects described above. It is readily available, is inexpensive and very effective. It is also not difficult to work into your eating routine: add olive oil and vinegar or lemon juice to your salads, and cook with olive oil. If you have not totaled 30 grams (2 tablespoons), then make up the difference by eating an extra teaspoon full of olive oil. This is not all! You need to cut down on processed foods as they are made with the wrong oils, such as safflower oil, corn oil, soybean oil and others. These are usually omega-6 containing oils that cause heart attacks and strokes. They are cheap oils use by food processors, and they are not doing anything for your health!

I would suggest that you read more about the powerful role of prevention that extra virgin olive oil has in our diet. Buy it and stick to it as a new healthy lifestyle habit. Two tablespoons a day is the weapon against disease!

Reference:

Ref.1. Current Medical Diagnosis and Treatment 2015, chapter 10 Heart Disease. By Thomas M. Bashore, MD; Christopher B. Granger, MD; Kevin Jackson, MD; Manesh R. Patel, MD: Heart Disease. Lange, 2015.

Mar
25
2015

Can Cancer Be Beaten?

For decades we have been indoctrinated that cancer can be beaten, but only marginal progress has been achieved with respect to effective cancer treatment modalities. So, we have become accustomed to be negative about the answer to the question “can cancer be beaten?” I like to propose that the answer is a resounding “yes”, but what has already been achieved needs to be further refined.

We know for a long time that there are distinct differences between the glycolytic cancer cell metabolism (“Warburg effect”) and the aerobic metabolism of normal cells.

In recent years the introduction of photochemical sensitizers followed by laser activation has made significant inroads regarding cancer treatment successes.

Animal experiments

Using a mouse model Ref.1 reported about the use of several photosensitizers to treat Ehrlich ascites carcinoma. The most effective substance was Hypericin, which is derived from Hypericum perforatum, also known as St. John’s wort. It showed the highest intracellular accumulation within the tumor cells, and the survival curves were the best with 25% cures after just one photodynamic treatment and a significant delay of mortality in the remainder of the animals. The control animals lived only 25 days on average, the Hypericin pretreated and photodynamic therapy treated animals lived about 70 days with the cured ones still being tumor free at 120 days.

Experiments like these have taught the medical profession that the type of photosensitive agent (e.g. Hypericin) matters, particularly how well it is taken up by the tumor. The other important factor is the absorption pattern of the agent, as the choice of laser light will determine how good a match there is between the wavelength of the laser and the inherent peak excitation of the agent (absorption spectrum).

Laser treatment of a group of melanoma patients

In Ref. 2 Dr. Weber described a report by Dr. M.A. Kaplan that was presented at the 2008 international laser conference in Helsinki. 76 patients with metastasizing melanomas were treated with Chlorin E6 (a natural photo-sensitizer) and intravenous laser for activation. 45% had reduced pain and improved life quality, in 22% of the cases lymph nodes with metastases either disappeared or became smaller; in 33% the metastases stopped spreading for 6 to 12 months.

Photodynamic therapy of a patient with duodenal cancer and liver metastases 

Dr. Michael Weber who is a specialist for internal medicine and the inventor of the Weber low-dose laser machine has treated cancer patients with photodynamic therapy (PDT) where his laser machine was used. I have described the Weber low-dose laser system before in a previous blog with uses for pain control.

One such cancer case was a female patient with a duodenal cancer (described in Ref.2). She had a primary duodenal tumor removed in 2009 using the Whipple procedure. At that time 4 liver metastases were noted. She saw Dr. Weber in 2010 because of two rapidly emerging liver metastases. A first photodynamic therapy (PDT) was done in May 2010. She felt much better. In June 2010 a second PDT course was given. An MRI scan of the liver in July 2010 no longer showed any metastases. However, in December 2010 metastases reappeared in her liver, which were treated with 3 more sessions of PDT in January of 2011. The metastases were still growing slowly. Dr. Weber decided to do a combination treatment with systemic PDT involving Chlorin E6, a photosensitizer and treating the metastases at the same time with interstitial laser therapy. Red light was used to stimulate the Chlorin E6. Miraculously the liver metastases became necrotic two weeks after this 20-minute treatment. Subsequently a surgical team from the University of Göttingen, Germany did a partial liver resection. At this point she appeared stable and cancer free.

Photodynamic therapy of a group of inoperable prostate cancer patients

20 patients with prostate cancer were treated with PDT between May and September 2014 (Ref.3). 20% of them had a complete remission of their cancers. 35% experienced a partial remission; another 35% had no further tumor progression. In 10% the tumors progressed. These patients were given the following photosensitizers: 80 mg Chlorin E6, 10 mg Hypericin and 150 mg Curcumin intravenously. Three hours after the intravenous photosensitizers had been given photodynamic laser therapy (PDT) was administered through a transparent, permanent catheter that allowed admission of the laser instrument up to the level of the prostate. With this approach the low-dose laser light penetrated the entire prostate gland. Three frequencies were employed that corresponded to the absorption peaks of the three photosensitizers, red light (658 nm) to activate Chlorin E6, yellow light (589 nm) to activate Hypericin and blue light (405 nm) to activate Curcumin.

In addition to PDT patients also received an immunostimulator preparation, called Gc protein-derived macrophage activating factor (GcMAF). Finally, in order to take advantage of the minimal differences regarding poor oxygenation of cancer cells versus good oxygenation of normal tissues intravenous oxygen was given with the oxygenation system of the German company Oxyven. This strengthened the normal tissue and weakened the cancer tissue.

The German researcher, Dr. von Ardenne did extensive research about the effects of oxygenation on healthy tissue versus cancer tissue. He postulated for instance that it would be possible to prevent cancer from metastasizing, if a person would exercise regularly while breathing oxygen through a mask. However, at this point this thought is not universally accepted.

When all the effects are taken together, the photodynamic therapy with photosensitizers and specific laser frequencies, the immune therapy and the oxygen therapy, the above successes in treatment outcomes can be explained as a synergistic effect: cancer cells are dying off from the PDT, macrophage activating factor stimulates the immune system and healing can start to occur.

Other end-stage cancer pilot studies

Dr. Weber reports about other pilot studies involving end stage breast cancer and pancreatic cancer (Ref.3).

Two cases of breast cancer with primary lesions measuring 3.5 cm or 5.0 cm were treated with Chlorin E6 and subsequent photodynamic laser therapy using the systemic and interstitial red laser of the Weber system. Within a few days tumor necrosis was visible and within 6 weeks after the PDT no tumor was present anymore in both cases.

Another case was an end stage pancreatic cancer in a 76-year-old man. This cancer was surgically removed in August of 2012. A few months later malignant ascites developed (cancer spread within the abdominal cavity). Chemotherapy with Gemzar had to be abandoned because of severe side effects. At this point PDT was started using Chlorin E6 twice with intraabdominal and intravenous red laser treatment. The patient also received a low-dose chemotherapy treatment with the pro-drug Xeloda, which gets converted into 5-fluoro-uracil (a standard chemotherapeutic agent). Using blue laser activation Xeloda becomes 100-times more powerful in destroying tumor cells. Only 3 months after this treatment the “incurable” pancreas cancer patient had been cured of his tumor and the malignant ascites. Initially the patient also had a secondary severe anemia that had to be treated with several blood transfusions before the PDT was started. Histology samples could no longer demonstrate presence of pancreatic tumor cells and the “intractable” anemia was cured as well.

Can Cancer Be Beaten?

Can Cancer Be Beaten?

Historic studies involving mega vitamin doses on end-stage cancer patients

Ref. 4 describes an experiment by Dr. Hoffer, the father of orthomolecular medicine. This is a branch of medicine that uses large doses of vitamins and minerals to rectify metabolic changes in various diseases. Dr. Hoffer treated 131 advanced cancer patients between 1976 and 1988 with a mixture of mega vitamins and minerals. There was a control group (not taking anything) and the experimental group. The results of this 9-year follow up study are depicted in the image below. The Y-axis represents the % of survival (at the zero point of time 100 % of each group were alive), the X-axis shows the time of survival in years. Note that the group of cancer patients taking meta vitamins is depicted with orange columns, the control group with blue columns. At 7 years of follow-up none of the controls survived. On average there was an 8 year survival advantage of the mega vitamin group versus the control group (control group 28% survival at year 1 of follow-up, mega vitamin group 34% survival at year 9 of follow-up). The supplements consumed were as follows:

Vitamin C, 10,000 to 40,000 mg orally daily; vitamin B3 (niacin or niacinamide) 300 to 3,000 mg; vitamin B6 (pyridoxine) 200 to 300 mg; folic acid 1 to 30 mg; vitamine E succinate 400 to 1,200 IU;  Coenzyme Q10 300 to 600 mg; selenium 200 to 1,000 micrograms daily; zinc 25 to 100 mg; calcium and magnesium supplement (2:1 ratio); mixed carotenoids as carrot juice; multivitamins and minerals.

Ref. 4 (page 347) explains that the Mayo Clinic did a study where they “duplicated” Dr. Hoffer’s study using only high doses of vitamin C, but failed to show any cancer fighting effect. However, they neglected to include all of the other cancer fighting supplements listed above. Vitamin C is an antioxidant, stimulates the immune system, but does not fight cancer by itself.

Dr. Hoffer's End Stage Cancer Experiment

Dr. Hoffer’s End Stage Cancer Experiment (click to enlarge)

Conclusion

Cancer treatments are entering a new phase where with the help of multiple treatment modalities combined (PDT, immunostimulation, oxygen therapy and low-dose laser activated chemotherapy) it is now possible to cure many cancers that were untreatable in the past. The tunnel vision approach of conventional oncology with a combination of surgery, chemotherapy and radiotherapy is obsolete for cases where cancer has metastasized. At this point the methods described in this blog are still considered experimental. In Germany they have done phase 1 and phase 2 trials as indicated above. Large phase 3 trials will have to be performed involving various types of cancers through conventional cancer agencies. Intravenous and interstitial photodynamic therapy is replacing the traditional toxic ways to treat cancer.  These new methods are effective with regard to both the primary tumor and metastases with hardly any side-effects.

Please note that Dr. Schilling has no commercial interest in Dr. Weber’s low-dose laser system, the links provided in this blog are merely there because of the newest information about low-dose laser photodynamic cancer therapy. Anybody who needs more information about the equipment or medical personnel wanting to buy the low-dose laser equipment can contact Jonathan Schwartz at this email: medicalmarvels@yahoo.com

References:

Ref.1: Þ. Lukðienë and P. De Witte: “Hypericin-based Photodynamic Therapy:I. Comparative Antitumor Activity and Uptake Studies in Ehrlich Ascite Tumor” Acta medica Lituanica. 2002. T. 9, Nr. 3, p. 195-199.

Ref.2: Michael Weber, MD: “New options of interstitial and intravenous laser therapy in oncology” The Intern.J. Med. Laser Applic. Vol1, July 2011, p.66

Ref. 3: Michael Weber, MD: ”Intravenous and interstitial photodynamic laser therapy: New options in oncology.” To be published 2015.

Ref. 4: Andrew W. Saul, PhD: “The Orthomolecular Treatment of Chronic disease”, Basic Health Publications Inc., Laguna Beach, CA 92651, 2014.

Feb
28
2015

Low Fat Diet Not Protective Of Heart Attacks

The British Medical Journal (BMJ Publishing Group, James J DiNicolantonio) published a critical editorial review regarding the lack of science behind the low fat diet guidelines. The low fat guidelines were enacted in 1977 in the US and in 1983 in England. The devastating fact was that it was based only on a study of 2467 men (not a single female included) and there was no evidence of lower heart attacks in the low fat diet group when compared to the normal diet control. Yet the guidelines were the cause of the obesity and diabetes epidemic that followed causing heart attacks and strokes. February, the month where we think about heart disease  is the appropriate month to discuss the findings of this British Medical Journal article that exposes it all.

The BMJ Publishing Group re-traced all of the data that were available at the time of the decision in 1977. There were six randomized clinical trials with a mean duration of 5.4±3.5 years where low fat diet was compared to normal diet. The researchers found that the authorities who wrote the dietary recommendations for a low fat diet should have come to the conclusion that there was no statistical difference between the experimental group and the control group. The summary of the present re-analysis of the studies that were available to the US government in 1977 and to the UK government in 1983 was as follows: “There was no statistically significant relationship between dietary interventions and all-cause mortality.”

It was noted that the all cause mortality was identical in the experimental group and the control group (370 deaths in both groups). No significant difference of coronary heart disease (CHD) was observed between the low fat diet group and the control group.

There was no statistically significant difference in deaths from CHD (heart attacks). The reductions in mean serum cholesterol levels were significantly higher in the intervention groups; however, this did not result in measurable differences in mortality from CHD or all-cause mortality.

What is further troubling is that the six randomized studies that were the basis of all of these observations included only 2467 men, but not a single woman. Yet the diet recommendations were made for both men and women alike.

The authors concluded “It seems incomprehensible that dietary advice was introduced for 220 million Americans and 56 million UK citizens given the contrary results from a small number of unhealthy men”.

Dr. Robert Olson of St Louis University warned Senator George McGovern that the studies did not support the dietary recommendations the Senator was about to announce. To this objection Senator McGovern replied: “Senators don’t have the luxury that the research scientist does of waiting until every last shred of evidence is in”.

There was very good evidence that dietary changes (low fat diet) will not change the rate of heart attacks and strokes. Yet the government committees in the US and in Great Britain did not consider this evidence. Other publications have examined the consequences of replacing saturated fats with carbohydrates in the recommended low fat diets.

Based on this link the following observations regarding low fat diets were made:

  1. In processed foods low fat diet meant that more sugar was added to bring the saturated fat content down. This has detrimental effects on insulin sensitivity and causes type 2 diabetes on the long-term. Small LDL particles are increased and so are triglycerides, while HDL is reduced. Blood clot markers increase, weight increases causing obesity. Saturated fats were replaced with polyunsaturated fats of the omega-6 type (including oils from corn, soybean, safflower and cottonseed).
  2. However, randomized controlled trials showed that when trans-fats and saturated fats were replaced with omega-6 polyunsaturated fats (without simultaneously increasing omega-3 fatty acids) increased death rates from heart attacks and strokes were found.
  3. The Anti-Coronary Club trial showed that more people died from heart attacks when saturated fat was replaced by polyunsaturated fat.
  4. The reason for the heart attack causing omega-6-fatty acids (from polyunsaturated fats) has been worked out in several research papers between 2006 and 2012 (cited in this link): they cause inflammation, cause cancer, weaken the immune system, lower the protective HDL cholesterol and increase the susceptibility of LDL cholesterol to be oxidized.
  5. When saturated fat was replaced by polyunsaturated fatty acids (omega-6) there was more breast cancer and prostate cancer.

This review ended with the statement that there is a lack of data supporting that a low fat diet helps prevent heart attacks and strokes. We have now clinical trials that numbered 347 747 participants. These trials showed that increased fat intake did not cause heart attacks. The women’s health Initiative included 48, 835 postmenopausal women showing that a low fat diet did not reduce cancer, and it also did not prevent heart attacks or strokes. All of this supports what has been summarized before in a critical review regarding “The Oiling of America“.

Low Fat Diet Not Protective Of Heart Attacks

Low Fat Diet Not Protective Of Heart Attacks

Conclusion

Enjoy saturated fat as it does not cause you harm. Cut out omega-6 fatty acids like oils from corn, soybean, safflower and cottonseed. Use virgin olive oil or coconut oil instead. Take regular supplements of omega-3 fatty acid (marine derived) to balance natural omega-6 fatty acids in turkey or chicken meat. You can eat cheese (in the US buy organic or imported cheeses from Europe where bovine growth hormone is illegal) and enjoy nuts.

It is most important to avoid sugar, honey and high fructose corn syrup as these all oxidize LDL cholesterol, which is the pre-stage for hardening of the arteries. The oxidized LDL cholesterol is incorporated into the plaques of arteries and leads to strokes and heart attacks. This also means that you must avoid all processed foods that contain sugar and high fructose corn syrup (read labels).

It is not that difficult to follow such diet recommendations as my wife and I have done this since 2001. We use stevia to replace sugar for sweetening (no calories, no effect on insulin). Do what’s good for your body!

Oct
24
2014

TACT Study Proves Effectiveness of Chelation

Even though the Trial to Assess Chelation Therapy (TACT Study) has been published in March 2013 (Ref. 1), it still needs to make its way into the common public knowledge. The National Institute of Health was noticing an “alarming 68% increase” of chelation therapy between 2002 and 2007. These patients had problems with previous heart attacks and others had angina due to coronary artery disease, so they sought relief through intravenous chelation treatments. The purpose of the TACT study was to see whether chelation treatments with EDTA were safe and whether they would show any benefits when compared to a placebo group.

TACT study design

A total of 1708 patients were randomized into two groups, 869 treated with EDTA chelation therapy and 869 in treated with placebo infusions of normal saline/dextrose. Treatments were blinded (nobody knew what was given in the intravenous). 134 research sites in Canada and the US were involved in this trial including the Mayo Clinic. Patients had to be at least 50 years old, but the average age was 65 years. They had all a prior heart attack, but not less than 6 weeks before enrolment; on average they did have their heart attack 4.6 years before enrolment. Participants had to quit smoking at least 3 months before entering into the study and if they had revascularization procedures (bypass surgeries or stents), this had to be done more than 6 months in the past.

31% of the study population had diabetes. 83% had revascularization procedures done in the past. The majority of patients were taking heart medications (72% beta blockers, 73% statins to lower cholesterol and 84% aspirin to thin the blood).

65% completed 40 infusions, 76% completed at least 30 infusions.

The chelation infusion was the standard infusion usually used in chelation clinics, namely containing EDTA (the chelating agent), salts and vitamins as indicated in this Mayo clinic summary report. The follow-up period was for 4 years. There was a drop-out of 30% for various reasons and 17% refused their consent to carry on in the study.

TACT Study Proves Effectiveness Of Chelation

TACT Study Proves Effectiveness Of Chelation

Results of the TACT study

Overall mortality in the chelation group was down 2.8% versus the placebo group. Heart attacks in the chelation group were down 19.5%; strokes down 20% and hospitalization rates were down 28.6% when compared to the values of the placebo group.

Diabetic patients (the subgroup of 31%) appear to have greater benefits from chelation treatments than the non-diabetic ones. The diabetic group benefitted by 39% with regard to risk reduction (strokes, heart attacks, mortality) versus the non-diabetic chelation group (only a 4% reduction).

Perhaps as important as the results of the effect of the chelation study versus the placebo group was the fact that the side-effect profile was indistinguishable between the two groups. This establishes for the first time that chelation therapy is safe and that it also has beneficial effects.

It is interesting that when the results of the TACT Study were announced at the 2012 American Heart Association meeting in Los Angeles, the majority of cardiologists did not believe the results (that chelation was effective); instead they were looking for alternative explanations to explain the effect and suggested that this study needed to be repeated again.

What are the benefits of chelation therapy?

Originally EDTA was used to treat children with lead poisoning in Germany. However, workers who were exposed to lead containing paints in various industries also were described to have improve significantly with EDTA chelation (see this chelation history link).

In the 1990’s environmental concerns about heavy metal poisoning of the earth atmosphere came more into the forefront. This 2007 paper reports about heavy metal poisoning in detail.

A new concern for those who like organic food is the use of copper sulfate by organic food growers to spray against fungal and bacterial growth on crop as copper sulfate is one of the 5 chemicals used in organic agriculture approved by the USDA.

Those who consume organic foods may inadvertently expose themselves to copper in their system. This will reduce zinc levels as zinc naturally counterbalances the effects of elevated copper levels. But normal zinc levels are needed for normal body function, particularly in males.

As I have explained in this blog before, chelation therapy and several other methods can detoxify the body. Pollution continues to play havoc with our system and we need to consider taking steps to counteract that. In this blog I explained that we live in a toxic world and I mentioned several steps we can take to counteract this including chelation therapy. Particularly heavy metals like lead, mercury, cadmium and copper will be reduced in the blood by intravenous EDTA chelation treatments.

Conclusion

I felt that I should take some time explaining the carefully conducted TACT Study that was a randomized double blind, government sponsored study examining the effects of chelation treatments. It showed that there were significant improvements in terms of cardiovascular recovery, but it also showed that it was entirely non-toxic. Chelation should be done by an American College for Advancement in Medicine (ACAM) certified practitioner to ensure that you get the same chelation treatment as described in the TACT Study. People with heart conditions will need 30 to 40 treatments (usually 1 week apart) to improve. However, a person with a normal heart who considers detoxification will only need 10 treatments initially (twice per week or weekly), then one every three months for maintenance. We all reside on the same planet and are exposed to ongoing pollution and food toxicity. Due to this reality the topic of chelation and detoxification is worth some serious consideration not only for patients with heart health issues.

More information about vitamins and detoxification: http://nethealthbook.com/health-nutrition-and-fitness/nutrition/vitamins-minerals-supplements/

Reference: 1. J. American Medical Association (March 27, 2013, Vol. 309, No. 12)

Last edited Nov. 8, 2014