Jan
21
2017

Effects Of Metformin On The Gut Microbiome

Matthew Andry, MD talked about the effects of metformin on the gut microbiome. He delivered his talk at the 24th Annual World Congress on Anti-Aging Medicine. The congress took place from Dec. 9 to Dec. 11, 2016 in Las Vegas. A lot of the sessions that I attended dealt with the gut flora and how it affects our health. This talk belongs to the theme of what a healthy gut microbiome can do for us.

History of metformin

Dr. Andry is a clinical associate professor of the Indiana School of Medicine. He pointed out that metformin is in use for a long time for type 2 diabetes, particularly, if fasting insulin levels are high. Metformin is a biguanide. It seems like it was isolated from French lilac (also known as Goats Rue). As a matter of fact in the middle ages physicians used this herb to treat “thirst and urination”. In retrospect we probably recognize these as symptoms of diabetes. Chemists were able to synthesize the active ingredient in this herb in the 1920’s.

Metformin reduces blood sugar without raising insulin levels

At that time it got the name metformin. Dr. Jean Stern was able to show in the 1950’s in clinical studies that Glucophage, the brand name of metformin was able to reduce blood sugar without raising insulin levels. Between 1977 and 1997 metformin enjoyed wide spread acceptance for treating diabetics. Most noteworthy, several clinical investigators demonstrated that diabetic patients on metformin lived longer and had less heart attacks than patients who receive other treatments.

Metformin is the first-line drug in the treatment of type 2 diabetes in children and adults. It is very popular with physicians who prescribe this drug throughout the world with 120 million prescriptions per year.

Off-label use of metformin

Metformin is beneficial for many other clinical conditions. Polycystic ovary syndrome (PCOS), obesity, prediabetes, metabolic syndrome and nonalcoholic steatohepatitis are a few examples of off-label use of metformin. In addition, metformin is also in use as an anti-aging agent as it elongates telomeres, which helps people to live longer. Equally important, researchers also found that metformin is a possible cancer prevention agent. In prostate cancer it was found to have an effect against prostate cancer stem cells. Not to mention that without these cells prostate cancer does not recur after surgical removal.

Action of metformin

For the reason that metformin increases the action of an enzyme, AMPK, this leads to lipid oxidation and breakdown of fatty tissue (catabolism). Furthermore, in the liver metformin inhibits the metabolic pathway of making sugar from fatty acids, called gluconeogenesis. Also, metformin causes increased uptake of sugar into skeletal muscle tissue. This is the reason for the stabilization of blood sugar. Then, metformin has two beneficial effects on the liver. First it stabilizes insulin sensitivity. This means that a given amount of insulin has a larger effect on the liver. Secondly metformin decreases the toxic effect of fatty acids on the liver tissue. In other words metformin has a healing effect on non-alcoholic steatohepatitis, a precursor to fatty liver and liver cirrhosis.

Metformin suppresses appetite

Metformin also has an effect on the appetite center in the brain. It helps many obese and overweight people, but not all to lose weight. The mechanism for that effect is in the hypothalamus, where the appetite center is located. Metformin inhibits the neuropeptide Y gene expression in the hypothalamus leading to reduced appetite.

Finally, metformin also normalizes the gut flora. This last point was the main focus of Dr. Andry’s talk.

Metformin and the gut

An animal experiment on mice showed in a study published in 2014 that metformin was stimulating the growth of a beneficial gut bacterium, Akkermansia. This is a mucin-degrading bacterium. But it also affects the metabolism of the host. The authors found that metformin increased the mucin-producing goblet cells.

Akkermansia muciniphila bacteria were fed to one group of mice. This group was on a high fat diet, but not on metformin. The mice showed control of their blood sugars, as did the metformin group. In other words manipulation of the gut flora composition could achieve control of the diabetic metabolism. The authors concluded that pharmacological manipulation of the gut microbiota using metformin in favor of Akkermansia might be a potential treatment for type 2 diabetes.

Effect of metformin on the gut flora

Akkermansia muciniphila bacteria comprise 3%-5% of the gut flora. It does not form spores and is strictly anaerobe, in other words oxygen destroys it. This is the reason why it is difficult to take it as a supplement. It is mostly growing in the mucous of the epithelium layer of the gut. The colon and to a lesser degree the small intestine of all mammalian species including the human race contain the highest number of Akkermansia bacteria.

Here are the effects of metformin on Akkermansia:

  • Metformin increases the Akkermansia bacteria count both in a Petri dish as well as in the gut of experimental mice. This suggests that metformin acts like a growth factor for Akkermansia.
  • Metformin increased the count of Akkermansia bacteria by 18-fold up to a maximum of 12.44% (up from the normal 3-5%) of all of the gut bacteria.
  • Researchers observed that the mucin layer of the lining of the gut in metformin treated mice was thicker. This suggests that the thickness of the mucin layer plays a role in increasing the Akkermansia count.

Effect of the gut on the body’s metabolism

Other researchers have investigated how a high fat diet can change the composition of the gut bacteria, which in turn are altering the body’s metabolism. Essentially a shift in the bowel flora can increase the gut’s permeability. The medical term for this is “leaky gut syndrome”. It leads to absorption of lipopolysaccharides (LPS) from bad bacteria in the gut. The end result is endotoxemia in the blood. This causes systemic inflammation in the body. Insulin resistance and obesity develop and often at a later date type 2 diabetes develops. It is interesting to note that often a high fat diet leads to these changes. But increasing Akkermansia bacteria in the gut or treating the patient with metformin can reverse this process.

An interesting mouse experiment showed that the changes that take place in the gut bacteria with cold exposure could be transferred to germ-free mice with no gut flora. This changed their metabolism proving that gut bacteria have profound influences on the metabolism. The fact that the gut bacteria have a profound influence on the metabolism is not only true for animals, but also for humans.

Akkermansia Facts

Here are a few facts about the Akkermansia bacteria.

  • The amounts of Akkermansia bacteria in the gut are inversely related to how fat we are. This is measured by the body mass index (BMI). Fat people have less Akkermansia in their guts.
  • A high fat diet lowers the amount of Akkermansia in the gut
  • Systemic inflammation is present with low Akkermansia counts
  • A high fat diet causes gut permeability (leaky gut syndrome).
  • Appendicitis and inflammatory bowel disease can be caused by low levels of Akkermansia.
  • Fat storage (both in subcutaneous fat and visceral fat) can be caused by low levels of Akkermansia.
  • Low levels of Akkermansia cause insulin resistance (associated with diabetes) and high blood sugars.
  • Brown fat’s ability to burn calories increased when Akkermansia was increased , which leads to weight loss.
  • Decreased Akkermansia counts lead to fat storage (weight gain).
  • Gut-barrier integrity improves when Akkermansia increased
  • Increased Akkermansia reduces visceral and total body fat
  • Synthesis of sugar in the liver (gluconeogenesis) reduces when Akkermansia is increased

We have 10 times more bacteria in the gut than we have cells in our body. The Akkermansia percentage of the gut flora can be decreased from antibiotics or food that contains traces of antibiotics. If there is a lack of Akkermansia species, there is more gut permeability, causing LPS increase and causing increase of inflammation in the body. This translates into high blood pressure, heart attacks, strokes, and degenerative neurological diseases like Parkinson’s disease, Alzheimer’s disease or MS. But it can also cause inflammatory bowel disease and autoimmune diseases.

What increases Akkermansia?

We can increase Akkermansia bacteria in the gut by eating Oligofructose-enriched prebiotics. Oligofructose belongs into the inulin type soluble fibers. It is found in a variety of vegetables and plants. This includes onions, garlic, chicory, bananas, Jerusalem artichokes, navy beans and wheat. But wheat can be problematic. Clearfield wheat is the modern wheat variety which is now grown worldwide. It is much richer in gluten and can cause problems with gut permeability.

Eating lots of vegetables and fruit will give you enough of oligofructose to maintain a healthy percentage of Akkermansia in your gut bacteria.

Metformin as pointed out earlier can is in use as pharmacotherapy. But I must emphasize that the use of metformin for dysmetabolic syndrome is off-label. There are real side effects of metformin. Lactic acidosis with an unusual tiredness, dizziness and severe drowsiness can develop. Also chills, muscle pain, blue/cold skin and fast/difficult breathing can occur. Slow/irregular heartbeat, vomiting, or diarrhea, stomach pains with nausea are other side effects.

Effects Of Metformin On The Gut Microbiome

Effects Of Metformin On The Gut Microbiome

Conclusion

Our gut bacteria are important for us, more so than you may be aware of. An anaerobe bacterium, Akkermansia makes up 3%-5% of the gut flora. This bacterium lives in the mucous layer of the lining of the gut and ensures that the gut wall is tight. When these bacteria are lacking (due to consumption of junk foods) the gut wall becomes leaky, which is why this condition has the name “leaky gut syndrome”. Irritating toxic substances can now leak into the blood stream and lipopolysaccharides are among them. This causes inflammation in the gut wall, but can go over into the blood vessels and the rest of the body including the brain. High blood pressure, obesity, diabetes, heart attacks, strokes, and degenerative neurological diseases like Parkinson’s disease, Alzheimer’s disease or MS can develop from the inflammation. But it may also cause inflammatory bowel disease and autoimmune diseases.

Eating lots of vegetables and fruit will give you enough of oligofructose to maintain a healthy percentage of Akkermansia in your gut bacteria. In particular, onions, garlic, chicory, bananas, Jerusalem artichokes and navy beans provide lots of oligofructose to support Akkermansia in your gut bacteria.

As pointed out earlier metformin as a drug is in use to treat dysmetabolic syndrome. I need to emphasize that the use of metformin is off-label. It is also important to remember, that with effects there are side effects of metformin.

It may be news to you, how our overall health depends so much on the health of the gut. With the knowledge that food can be your medicine, choose your foods wisely. Add some or all of the above named foods that help you support beneficial gut bacteria, and take care of your health!

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Jan
14
2017

How To Avoid Being Hungry

Dr. Ludwig gave a lecture about how to avoid being hungry at a conference in Las Vegas. The actual topic was “Always Hungry?” I attended the 24th Annual World Congress on Anti-Aging Medicine (Dec. 9-11, 2016) in Las Vegas where this lecture was given. Dr. Ludwig is a Harvard-based endocrinologist who has been researching weight loss methods and obesity for over 20 years. Here is a list of his major publications.

Dr. Ludwig stated that the low fat/high carb diet popular in the1980’s until the early 2000’s was misguided and probably even harmful. The theory at that time was that obesity was caused by too much saturated fat. This has since been proven to be wrong. Instead it has been proven that increased sugar intake is responsible for the obesity wave.

General information about weight gain

The carbohydrate-insulin model states that without insulin you cannot gain weight, because in order to store fat in fatty tissue you need insulin to transport fatty acids across the cell membrane of fat cells.

In this context it is important to note that high glycemic index food increases the blood sugar. This leads to stimulated insulin production, and the liver converts the extra sugar into fatty acids that get deposited as fat in fatty tissue.

The glycemic load from a person’s diet is the single best predictor for a rising blood sugar level. After food intake the blood sugar goes up, glucagon goes up, epinephrine goes up within 4 hours. It is the epinephrine, which after 4 hours makes you hungry again.

The nucleus accumbens is the addiction center. At 4 hours after a high glycemic index milk shake the nucleus accumbens was stimulated in 12 subjects of a double blind trial.

The nucleus accumbens does not work in isolation. It is not only involved in food satisfaction, but also in sexual satisfaction and even plays a role in satisfaction that some people get from playing video games.

Low-carbohydrate, Mediterranean or low-fat diet

In an Israeli study from the New England Journal of Medicine in 2008 investigators were interested to find out which diet was helping people to lose most weight.

322 moderately obese subjects that were aged 52 years on average were randomized to one of the following diet groups.

They compared

  1. a low fat diet (Atkins type, restricted calorie) with a
  2. Mediterranean diet (low carb, restricted-calorie) and a
  3. Low fat/high carb diet (low fat, non-restricted-calorie)

What was the result? The mean weight losses were: 2.9 kg (low fat group), 4.4 kg (Mediterranean diet group), and 4.7 kg (low fat/high carb group). Of the 272 participants who had completed the intervention after two years of the study the weight loss was 3.3 kg, 4.6 kg, and 5.5 kg in the same sequence as above.

Next the researchers examined the ratio of total cholesterol to high-density lipoprotein cholesterol, which is a measure for the heart attack risk. It was 20% lower from the baseline in group 2 (Mediterranean diet group). The low fat groups (group 1 and 3) were 12% lower from the baseline.

36 subjects had diabetes. There was a clear winner with respect to lower fasting blood sugar and insulin levels, namely the Mediterranean diet (group 2).

The authors concluded that the Mediterranean diet is preferable to low fat diets as they have shown an improvement in lipid profiles and in control of diabetes.

The “POUNDS LOST” study

This was a 2-year study that investigated 4 different lower calorie diets to help people lose weight. Despite the significant difference in diet composition, these 811 free-living overweight or obese adults ages 30-70 from Boston, MA and Baton Rouge, LA lost 16 pounds at 6 months and 9 pounds at the end of two years. The diets were 1) low fat (20%) or 2) high fat (40%) 3) average protein (15%) or 4) high protein (25% of total calories).

The authors concluded that any reduced, calorie-controlled diet would help obese or overweight people to achieve weight loss that lasts. It is interesting that it did not matter whether the diet was low or high in fat, or had low or high protein content. What did matter was that all diets were low in sugar.

Sugar is the driving force

Dr. Ludwig pointed out that without insulin you couldn’t gain weight. High glycemic index food increases blood sugar. The glycemic load is the single best predictor to indicate whether a person will gain weight or lose weight when you consume food. It is an irony that in the 1980’s and 1990’s the wrong assumption that a low fat/high carb diet would be heart healthy created the obesity wave. We have abundant data available that show otherwise: high sugar content of food brings the calorie count up as everybody can read on the food labels.

Sugar stimulates the food addiction center

This will lead to weight increase, which has been abundantly proven. Sugar also stimulates your nucleus accumbens, the food addiction center. As you probably know it is extremely difficult to get out of this food addiction cycle unless you cut out sugar. You even need to go one step further and include many starchy foods that will within 30 minutes of digesting them turn into sugar. Your system makes no difference whether you eat a few teaspoons of sugar or two slices of white bread. The response of your pancreas is insulin, which gladly stores the fatty substances your liver made as fat.

How to get out of the vicious food cycle

As the quoted publications and many other ones have shown, it only matters that you limit your refined carb intake. You can vary the fat content and you can vary the protein content and still lose weight provided you watch the low carb intake. You also need portion control, which is a given! Study glycemic index and glycemic load sites on the Internet. The links I provided are just some examples. The more you educate yourself about carbs, the better for you. Note that many fruit and vegetables belong to the low-glycemic load/index foods. Avoid the high glycemic index foods like dates and cornflakes. Stick to low-glycemic index foods, which are less than 55. With regard to low-glycemic load food the values should be below 10.

The Mediterranean diet is a very desirable diet, which has been proven to be anti-inflammatory.

The zone diet of Barry Sears is also an anti-inflammatory diet and he summarizes this in this link.

How To Avoid Being Hungry

How To Avoid Being Hungry

Conclusion

I have summarized the content of a talk given by Dr. Ludwig. We learnt from this that sugar and refined carbs are the driving force that leads to “feeling hungry”. This stimulates your nucleus accumbens, the food addiction center. Let’s assume that a person is obese or overweight and wants to lose some weight. You need to start by being strict with yourself. Cut out sugar and high-glycemic foods. This will remove the food addiction factor that keeps you going back to the wrong, high calorie foods. You will also consume more low calorie vegetables and fruit, which have more fiber that fills you up.

Monitor your body mass index

Once you are used to the new way of eating, there is no need to count calories. I recommend that you weigh yourself daily on body composition scales and record the results. This allows you to monitor your body mass index (BMI), your weight, your fat percentage, and your muscle percentage. Typically you will lose 2 to 3 pounds per week on such a low-calorie diet. Later the weight loss will slow down to 1 to 2 weeks per week until you reach your goal. Don’t go lower than a BMI of 21.0 to 22.0 and discuss your goal with your doctor.

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Jul
16
2016

Mediterranean With Healthy Fat

If you want to lose weight, have you considered eating Mediterranean with healthy fat? A lot has changed in recent years regarding recommendations for healthy food intake. In the eighties and nineties there was a recommendation for a  low fat diet, which unfortunately was high in carbs and led to obesity. We learnt from this that carbohydrates break down in the gut into sugar. This converts into fatty acids, which go in storage as fat.

Studies regarding diets with unhealthy and healthy fats

Prospective study in the US

Here is a prospective study that followed 120,877 U.S. women and men over a longer time. Every 4 years there was weight gain of 1.69 lbs. for potato chips, 1.28 lbs. for potatoes, 1.00 lb. for sugar-sweetened beverages, 0.95 lb. for unprocessed red meats and 0.93 lb for processed meats. On the other hand from vegetables there was a weight loss of −0.22 lb., for whole grains −0.37 lb., for fruits −0.49 lb., for nuts −0.57 lb. and for yogurt −0.82 lb. The researchers checked cheese out and found it mostly neutral in terms of weight gain, while butter did cause weight gain.

Lancet study from Spain

In a study from Spain that was published in the Lancet in June 2016. The researchers followed 7447 asymptomatic men (aged 55–80 years) and women (aged 60–80 years) for about 5 years. They all had type 2 diabetes and three or more cardiovascular risk factors. They were randomly assigned to three Mediterranean diet types: a Mediterranean diet with olive oil, a Mediterranean diet with nuts and a control group on a low fat Mediterranean diet.

Weight loss when on Mediterranean diet

The interesting finding after 5 years was that there was weight loss around the waist in both the patients on the Mediterranean diet with nuts and with olive oil. Their weight loss was 0.95 lbs. for the olive oil group and 2.82 oz. in the Mediterranean diet group with nuts. The Mediterranean diet group with olive oil had lost 0.22 inches in the waistline, the other group on nuts lost 0.38 inches. These are hardly impressive losses! The researchers concluded that fat restriction is not necessary on the Mediterranean diet, as there was no weight gain with unrestricted healthy fats after 5 years.

Summary from a cardiologist

Dr. Dariush Mozaffarian, a cardiologist and epidemiologist of the Tufts Friedman School of Nutrition Science & Policy wrote an editorial regarding this Spanish study: ”A handful of nuts may be 160 calories, which is more calories than a can of Coke, but that doesn’t mean the can of Coke is a better choice”. He added: “Salt, sugar, starch, processed food and trans fats should be off the menu, not fat. Healthy foods are healthy foods, and bad foods are bad. It doesn’t matter, if the food is low fat or high fat. This is a separate issue.”

Mediterranean With Healthy Fat

Mediterranean With Healthy Fat

Conclusion

When wanting to lose weight, the key is to pay attention to your carb intake. Make sure it consists of unrefined carbs. You will do this if you eat vegetables and fruit. Cut out sugar and starchy foods as much as you can. Have lean, clean meats, but avoid red meat except perhaps for every two weeks some grass fed beef. Eat fish (important for its content of omega-3 fatty acids), also enjoy yogurt, nuts, olive oil and avocados. It is an extra benefit if you add regular exercise to this as well. You will notice that you gradually shed the unnecessary pounds. This is not a program for just a month or two. To stay well, make it a new lifestyle!

Apr
23
2016

Healing Powers Of Green Tea

Powerful catechins that are a special form of bioflavonoids provide the healing powers of green tea. Researchers have proven that these catechins are only in green tea, not so much in black tea. The most effective of several catechins contained in green tea is EGCG, which stands for EpiGalloCatechin-3-Gallate. It crosses the blood/brain barrier and is very important for the protection of the brain from Alzheimer’s disease. But green tea or green tea extract has a diversified pharmacological action. Researchers said that green tea protects you from cardiovascular disease, from obesity, from diabetes, from autoimmune disorders, from cancer, from Alzheimer’s and dementia.

In the following I like to comment on how green tea or its extract can protect from all of these diseases.

Alzheimer’s disease

Although there are 5 or 6 approved anti-Alzheimer’s drugs, none of them work for very long. They may at best postpone the deteriorating memory for 6 months, but then the effect of the drug wears off. The reason is that the drugs do not stop the production of the deadly beta-amyloid. It is the beta-amyloid that damages nerve cells that you want to preserve so you can think and memorize. In contrast a simple phytochemical, the catechin EGCG has been shown in animal experiments and in human trials to stop beta-amyloid production and increase solubility of beta-amyloid fragments in the brain. The end result is better memory and no further deterioration.

Two studies showing less strokes and better working memory processing with green tea

In a study of 13,988 elderly Japanese observed over 3 years the group that consumed 3 to 4 cups of green tea daily had 33% less strokes, cognitive impairment and osteoporosis.

Researchers at the University of Basel, Switzerland enrolled 12 healthy volunteers aged 21 to 28 and fed them extracts of green tea or placebo fluid via feeding tubes. They did this to rule out taste as a factor. The patients underwent functional MRI scans and they also received memory-stimulating tasks. Only the green tea extract was boosting activity in the frontal brain of the subjects. This was located in a specific area, called dorsolateral prefrontal cortex. This area has a connection with language comprehension, reasoning and learning. It also switches short-term memory into long-term memory, called working memory processing.

Healing powers of green tea through new nerve cell development

Researchers showed with animal experiments that green tea extract protects nerve cells from the toxic effect of beta-amyloid. At the same time green tea extract triggers the production of new brain nerve cells (neurons). This is really good news for Alzheimer’s disease patients and their families: green tea extract delays further memory deterioration and stimulates the development of new nerve cells in the brain!

Cardiovascular disease

In a 2006 Japanese study 40,530 Japanese adults aged 40 to 79 years without history of stroke, coronary heart disease, or cancer at baseline were observed for 7 years. Diaries were kept about how many cups of green tea each person was drinking per day. The prevention of heart attacks and strokes was the the biggest effect of green tea extracts.

Men had a mortality reduction of 12% for heart attacks when they drank 5 cups or more of green tea; in women the corresponding mortality reduction for heart attack was 31%, a bigger effect. Overall mortality from strokes was lower than from heart attacks. This made the effect of green tea consumption even more beneficial with respect to stroke prevention. This study did not show any cancer prevention effect for green tea.

Obesity

It appears that green tea increases heat production and burns fat in the process. There was a small effect in terms of weight loss and a beneficial effect increasing the protective HDL cholesterol in this 2012 Polish study on obese patients. The authors compared either 379 mg of green tea extract, or a placebo, daily for 3 months. They concluded: “The results of this study confirm the beneficial effects of green tea extract supplementation on body mass index, lipid profile, and total antioxidant status in patients with obesity.”

Diabetes

Although there are claims in some studies that green tea would prevent diabetes, this question was thoroughly investigated in this Chinese 2014 study.

Researchers did not see any effects on fasting blood sugars or on hemoglobin A1C values. Hemoglobin A1C is a very sensitive indicator for the presence or absence of diabetes. All these lab tests showed no change following consumption of green tea or green tea extract. Forget using green tea for diabetes prevention; cut out sugar and starchy foods instead.

Autoimmune disorders

Sjogren’s syndrome and lupus are both autoimmune diseases. Green tea extract has shown in humans that symptom severity can improve; green tea polyphenols (GTPs) possess anti-inflammatory properties that benefit patients with autoimmune diseases.

In an animal model arthritis researchers determined that T helper cells are weakened and bone resorption is inhibited by EGCG from green tea extract.

Researchers at Harvard Medical School, Boston, MA have noted that green tea extract is useful in calming down the immune response in autoimmune diseases. They concluded: “Altogether, these studies identify and support the use of EGCG as a potential therapeutic agent in preventing and ameliorating T cell-mediated autoimmune diseases.”

Cancer

Many researchers found that EGCG from green tea extract has immune modulatory effects. Furthermore, they saw a positive effect when patients received EGCG in combination with chemotherapy. A combination of cisplatin therapy with green tea extract has been found to have more effects on colorectal cancer and ovarian cancer than each one on its own. Similarly chemotherapy of breast cancer had better results in humans when EGCG from green tea extract was added as an immune modulation. More research, particularly in humans is needed to fully understand the mechanism of action of EGCG.

Toxicity of green tea extract

Animal experiments showed that higher doses of green tea extract could cause toxicity in the liver and in the nose of rats and mice. I was not able to find objective evidence for green tea toxicity in the PubMed system with respect to humans.

Healing Powers Of Green Tea

Healing Powers Of Green Tea

Conclusion

Perhaps the most important discovery regarding green tea extract is as follows. It crosses easily through the blood/brain barrier into the brain. This can postpone Alzheimer’s disease and can even lead to new neuron formation. The beneficial cardiovascular effects are also useful and combine well with exercise and good nutrition for prevention. Particularly stroke prevention is a useful property of EGCG from green tea extract. The effect on obesity is marginal whereas there was no effect of green tea on prevention of diabetes. The immune modulatory effect of green tea extract is useful in the treatment of autoimmune diseases and of cancer. Existing treatments for these conditions are becoming more effective by adding green tea extract.

Mar
26
2016

Heart Attacks Can Kill

We rarely hear that heart attacks can kill; we are more likely to hear that an ambulance transported a person to the hospital with a heart attack. The doctors placed a stent or two and the person left the hospital two or three days later, fully recovered.

What silent changes occur before a heart attack?

A heart attack does not happen out of nowhere. There can be one or several risk factors present before, like smoking, a lack of exercise, being overweight or obese from eating too much sugar, consuming sugary drinks and eating lots of starchy foods. This will have changed the cholesterol fractions with the bad LDL cholesterol being high and the good HDL cholesterol being low. Triglycerides in this setting are also usually high. The end result is that the lining of the body’s arteries, including the coronary arteries close off to the point where blood has a harder time flowing through the opening of the coronary arteries. One day the heart muscle reports severe pain from a lack of oxygen and nutrients. There are essentially three coronary arteries that supply oxygen and nutrients to the heart muscle. For details follow this link.

Often people have 50% to 60% of coronary artery narrowing, but do not know about this. There are tests available that a person could do to check the amount of hardening of the arteries (for instance the IMT test, see below).

What happens after stent placement?

The interventional cardiologist inserts a catheter from a wrist artery or elbow artery backwards through the aorta and from there into each of the openings of the coronary arteries. By injecting a dye the radiologist can use X-rays to show the condition of each of the coronary arteries. If the physician identifies a blockage, angioplasty can overcome this. With an angioplasty an instrument pierces through the atheromatous deposits and reopens the coronary artery. To prevent re-stenosing, the cardiologist places a wire mesh stent that opens up upon withdrawal of the instrumentation. The end result is that the previous obstruction of the coronary artery is fully functioning again and the stent keeps the coronary artery open. The cardiologist may have to place two or more stents during the same procedure.

A 5-year follow-up study summarized the outcome after stent placements in 1095 patients with 3-vessel coronary artery disease. Percutaneous coronary intervention, a fancy name for saying “angioplasty combined with stent placement” had a 5-year mortality rate of 14.6%, 9.2% heart attack rates and 24.4% reoccurring blockages requiring repeat procedures to reopen the coronary arteries. There were 3% strokes over 5 years demonstrating that not only heart vessels, but also brain vessels were affected by the hardening of the arteries.

What is heart failure?

You may think that the heart would now be entirely back to normal. But this is a gross simplification. The heart functions like a pump, and we know that pumps can fail. In the past when the heart stopped functioning, the person would die. This was the case because there was a complete irreversible closure of one or more coronary arteries. As a result the muscle of one part of the heart, typically involving the left heart chamber would stop functioning. The left anterior descending coronary artery supplies this part of the heart. The left heart chamber is the main pump that pushes blood out into the aorta and from there through the whole body. We need the left anterior descending coronary artery to be open and supply nutrients and oxygen to this vital heart pump all the time.

Ventricular fibrillation and heart attack

When there is a 70% to 80% narrowing of this artery and the heart is not yet failing, there can be life threatening irregular heartbeats. They are called ventricular fibrillation and they come from a lack of oxygen. This makes the heart muscle contractions no longer effective.  as they are no longer synchronized making the heart muscle beat as one unit. This causes acute pump failure and the patients dies. The other possibility is that the patient has a massive heart attack that kills a large portion of the heart muscle off (called myocardial infarction or heart attack). If the patient is not lucky to have immediate access to a hospital with an interventional cardiologist waiting for him or her, even angioplasty and stent placement will not revive the dead portion of the heart muscle and the patient will not survive.

Measuring ejection fraction

Using a echocardiography the ejection fraction can be determined. This is a measure of how well your heart empties with each heartbeat. Normally it would be between 50 and 70. Below 50 indicates that heart failure is present.

Patients who had a mild heart attack may only have an ejection fraction of 40 and get short-winded with mild activity. Other reasons for mild heart failure can be atrial fibrillation. This is  a common chronic condition in older patients where the atrial chamber is not contracting properly, but fibrillating. Another cause can be inadequate treatment of high blood pressure. In this case the heart muscle has a hard time maintaining blood flow against an abnormally high pressure gradient.

Lowered ejection fracture indicating various degrees of heart failure

Many patients who had a heart attack and were quickly treated with angioplasty and stent insertion have had some minor persistent damage to the heart muscle resulting in abnormal echocardiograms with lowered ejection fractions. In the past without the acute intervention they would likely not have survived. Now due to modern medical technology these patients did survive, but they are left with a mild degree of heart failure, as a certain portion of their heart muscle has died off.

What kills the patient with a heart attack?

As explained above, when the heart muscle no longer is able to function as a pump, the patient dies. This can come from irregular heartbeats, particularly ventricular fibrillation that does not respond to emergency treatment with a defibrillator. This is an electrical device that resets  The reason can also be a heart attack that kills a significant part of the heart muscle. Ventricular fibrillation often occurs when not enough oxygen reaches the heart muscle and the special nerves that coordinate that heart muscle fibers to contract as one unit. Regular monitoring of the carotid intimal-medial thickness (IMT) by ultrasound will give a fairly accurate test for coronary artery hardening as the two are closely related.

Elective angioplasty or stent placement

The doctor who has a patient in danger of deterioration can refer the patient to a cardiologist. Angioplasty and stent placement can prevent further deterioration for the time being. It is much safer to do these procedures electively rather than during an emergency when the patient is in distress.

Prevention of heart attacks, any volunteers?

Following the overview above it becomes apparent that prevention to not get heart disease is the best approach with regard to hardening of the arteries. This can be achieved by doing the following:

Adopt a Mediterranean diet

You must abandon the Standard American diet. This means no processed food, no refined sugar intake, avoid as much starchy foods as possible. Adopting a Mediterranean diet or a DASH diet is a first step. The DASH diet was developed to help patients with high blood pressure to reduce their blood pressure through the use of this diet. Reducing blood pressure will also reduce the risk of heart disease.

Avoid excessive alcohol intake

Avoid excessive alcohol intake (more than two drinks per day for men and more than one drink per day for women) as the toxic effect of alcohol kills heart muscle cells. This in turn leads to heart failure.

Regular physical exercise

Regular physical exercise will condition your lungs and heart and improve your cardiac output. By having bigger reserves the person becomes more resilient to developing a heart attack.

Increase your fiber intake

Increasing your fiber intake to 30 to 35 grams per day using vegetables and fruit and additional fiber supplements. Common fiber supplements consist of psyllium husk and/or others from the health food store. Take it in the morning with breakfast and with lunch. By avoiding extra fiber at dinnertime you sleep better at night. It turns out that fiber intake is very important to lower LDL cholesterol and triglycerides by interfering with the enterohepatic pathway that leads to recirculation of bile salts rich in these fatty substances. The net results are lower LDL cholesterol and triglyceride levels and higher HDL cholesterol (the good cholesterol) levels.

Vitamins and supplements

Take some vitamins and supplements. Vitamin B2, B6, B12 and methyl folate will support methylation pathways. Vitamin D3 in a good dose like 5000 IU per day or more and vitamin K2, 200 micrograms per day will remove calcium out of the arteries and transport it into the bones; this effectively prevents hardening of the arteries and prevents osteoporosis at the same time. Omega-3 supplements (EPA/DHA) are very useful to keep inflammation under control and delay hardening of the arteries; it helps to lower LDL and increase HDL.

Bioidentical hormone replacement

Have your hormones checked. Some doctors do not feel comfortable doing this; maybe you want to see a naturopath about it instead. Your body needs the hormone receptors satisfied by adequate bioidentical hormone levels; otherwise you age prematurely and give up body functions that you would rather keep. Normal hormone levels prevent osteoporosis, premature hardening of the arteries, Alzheimer’s, erectile dysfunction and premature wrinkles. The essential hormones involved in cardiovascular disease prevention are thyroid hormones, sex hormones and in some aging people also human growth hormone.

Measuring heart function

Once every 2 years it would be good to measure your heart function as is outlined in this blog.

17 causes of blood vessel disease

There are many more factors that have been identified by researchers to contribute to hardening of the arteries.  It is useful to read this and think about which of these factors may apply to your case.

Heart Attacks Can Kill

Heart Attacks Can Kill

Conclusion

I have explained that hardening of the arteries is the cause of heart attacks. This is caused by a multitude of factors including sugar and processed food overconsumption, smoking, excessive alcohol intake, obesity, undertreated high blood pressure and diabetes. Simply doing angioplasties and placing stents will not stop the process of what led to the heart attack in the first place. Almost 15% died within 5 years following those procedures and 9% got another heart attack. They did not change their diets and stayed inactive.

Congestive heart failure can kill

There is another sad aspect about clogging of coronary arteries. The more coronary artery flow we lose through hardening of the coronary arteries, the lower our ejection fraction. This means our heart as a pump is failing more and more. When we reach the point of less than 50% of ejection fraction, we enter disability country. This means clinical heart failure, forcing us to wear continuous oxygen masks and being unable to exercise or walk. Heart failure is as deadly as terminal cancer having a very high mortality rate.

Concentrate on prevention now, because heart disease remains the number one killer. Remember that we can largely prevent heart disease when we follow the steps mentioned above!

More info about heart attacks: http://nethealthbook.com/cardiovascular-disease/heart-disease/heart-attack-myocardial-infarction-or-mi/

Dec
19
2015

Beer Belly Bad News

You heard the expression “beer belly”, but now we learn “beer belly bad news”. It is an unflattering term for increased abdominal girth, especially in males. It is quite often that this picture is found in middle-aged men who consume more beer than what is good for them, but they may also mill around the hot dog stands at the ball game instead of being physically active. Any leftover calories are stored as belly fat, which protrudes their stomach as if they were pregnant.

There is a big difference between belly fat and body fat. Belly fat is metabolically much more active. Body fat is more sessile. So, it is the belly fat we need to do something about as this has been shown to be associated with heart attacks, strokes and diabetes.

 

Abdominal girth to hip ratio instead of BMI

Originally it was thought that excessive weight would best be measured with the body mass index (BMI). But subsequently it was shown that athletes with well-developed muscles could have BMI’s that were in the overweight (between 25.0 and 30.0) or even obese category (more than 30.0). Also, some people with heavy bones can have excessive BMI values despite them being normal based on other measurements. The new measurement is the old fashioned abdominal girth to hip ratio.

Weight gain leads to metabolic syndrome

You measure the abdominal girth, the hip girth and divide the abdominal girth by the hip girth. Normally this should be 80% (=0.8) or less for women and 90% (=0.9) or less for men. But a person with a beer belly will have ratios of 1.2 or 1.5.

If you take blood tests of that person you would also find elevated triglycerides, lowered HDL cholesterol (the protective cholesterol) and elevated LDL cholesterol (the bad cholesterol). In addition, we know from studies that often the insulin level is elevated in the sense of hyperinsulinism. In fact that person has often the metabolic syndrome, which is a characteristic change of the metabolism in an obese person. The blood is thicker with clotting factors floating around, there are inflammatory kinins that circulate and these factors work together on causing hardening of the arteries.

Why is a beer belly dangerous?

There are not only cardiovascular risk on the long-term causing heart attacks and strokes down the road. There is a danger of fat deposits in the liver, called fatty liver disease.

In time this can turn into liver cirrhosis and in some cases develop into liver cancer. Because belly fat causes inflammation in the system including in the lining of the blood vessels, this can in time also affect the immune system, weakening it and eventually allowing cancer to develop. Common cancers that are associated with obesity are breast cancer, ovarian cancer and uterine cancer in women, prostate cancer in men and pancreas and colon cancer in both sexes.

Estrogen from aromatase in beer bellies

In men beer bellies produce a lot of estrogen, the female hormone. This is so because fat tissue contains the enzyme aromatase that metabolizes male hormones into estrogen. Estrogen in men is only good in traces, but when the body produces it massively, it will counter testosterone production and will cause heart attacks and strokes.

What can you do about a beer belly?

We need to understand how beer bellies develop. One of the sources of fat from beer bellies is the consumption of foods that contain a lot of fructose. Food manufacturers have been diligent in mixing high fructose corn syrup into sugary drinks and into a myriad of processed foods.

Sugar itself can only be processed and stored until the glycogen stores in the liver and the muscles are filled. The liver metabolizes a surplus of sugar into triglycerides and LDL cholesterol. This is also the case for any fructose that comes from metabolized sucrose (table sugar) and from the high fructose corn syrup popular with the food processing industry. One problem is that fructose can only be processed by the liver, while glucose gets directly taken up by cells with the help of insulin.

German obesity wave after WWII in the 1960’s

The surplus of fructose metabolizes into triglycerides and LDL cholesterol before the body stores it as fat in fat cells. Unfortunately a lot of the fat will end up between your guts, in the liver as fatty liver and in the beer belly, a metabolically more active form of fat.

The sad part is that in the 1960’s I have seen the German economic wonder (“Wirtschaftswunder”) where many mid fifty to mid sixty business men died as a result of obesity and subsequent heart attacks and strokes. At that time Germans who were starving during World War II lived it up. This was in the late fifties and 1960’s. They ate whatever they could: cakes, fatty cheeses, whipped cream, fatty foods like pork roasts and beef.

Unhealthy hydrogenated fats, starchy food and sugar caused beer bellies

They also consumed loads of bread, buns, pasta and sugar. Margarine also became popular with its hydrogenated fatty acids that also contained free radicals. The end result was that they gained weight, did not exercise and developed their beer bellies.

In the 1980’s the school of thought was that saturated fatty acids  were responsible for heart attacks, strokes and obesity.  A low fat/high carb diet became popular and continued to steadily increase. Sure, the hydrogenated fatty acids did not help and should be cut out. But the bigger problem was the consumption of high fructose corn syrup and over-consumption of high glycemic-index carbohydrates.

Steps of how to get rid of the beer belly

Here is the solution of what to do get rid of the beer belly.

Eliminate sugar and high fructose from diet

Remove sugar and high fructose corn syrup from your diet.

Remove empty starches from your diet

The second effective step is to cut out as many empty starches that you can cut out like white rice, bread, sweets, cookies, cakes, ice cream and pasta. Starchy foods metabolize in the gut into sugar, which causes an insulin response. The extra insulin is responsible for developing inflammation in the arteries, which eventually leads to heart attacks and strokes.

Regular exercise

Exercise on a regular basis. This will produce HDL cholesterol, the protective cholesterol, which balances LDL cholesterol.

Rebalance your food intake

Perhaps the most important step is to rebalance your food intake. With this I mean that you replace high glycemic-index carbs with low glycemic-index carbs. This means you will eat a lot of salads, steamed vegetables, and fruit. This gives you a lot of extra fiber, which your system needs to slow down the rate of sugar absorption. It also  helps you to lower LDL cholesterol and detoxify your body in the gut where fiber binds toxins.

Moderate your alcohol intake

If you are heavily into alcoholic drinks, this is another source of refined carbohydrates. They metabolize into LDL cholesterol, triglycerides and can cause fatty liver disease and liver cirrhosis. A moderate consumption of alcohol (one drink for women per day and two drinks for men per day) lowers the risk of heart attacks and strokes, while excessive alcohol intake increases the risk.

Bioidentical hormone replacement

Bioidentical hormone replacement may be something you have not heard about. But if you are a woman above the age of 40 or a man above the age of 50 chances are that you need some hormone tests. As a male, your natural hormone production from your testicles or adrenal glands is likely not keeping up.  As a woman, your ovaries or adrenal glands are no longer keeping up with the demand of regular life. Part of the aging process is that the production of our sex hormones slows down. It does so shortly before menopause in women and shortly before andropause in men.

Lack of function of key organs in menopause and andropause

This will not only manifest itself in hot flashes and sleep disturbance in women. Men experience erectile dysfunction and grumpiness. Eventually this leads to a lack of energy production in the heart, the brain and other organ systems. When these organs have sex hormone receptors, but circulating sex hormones are missing, they cannot function optimally.

Lack of hormones causes heart attacks, strokes and cancer

A lack of hormones translates into yet another cause of heart attacks, strokes and certain cancers. This is an area where conventional medicine disagrees with anti-aging medicine. Years in general practice have taught me that heart attacks, strokes, colorectal cancer and pancreatic cancer happen more often when hormones are missing in both sexes. Cancer of the breasts, uterus and ovaries and prostate cancer are more common when sex hormones are missing. These cancers occur when natural sex hormone production declined.

On the other hand, with bioidentical hormone replacement the metabolism of all cells will return to normal. With this the likelihood of not developing all these illnesses at an earlier time is diminishing as well. It is not a panacea for eternal life, but it will add significant longevity. And with this comes the knowledge that you will not get premature disabilities, which is what we all need.

Beer Belly Bad News

Beer Belly Bad News

Conclusion

We need to assess our food intake habits and cut out the items that contribute to the beer belly. Next we need to ask ourselves what other change in lifestyle we require.  Think about anything to improve our body shape and our energy metabolism. Life is too precious to just throw away years of fruitful living in our golden retirement years. Work on these factors in midlife or even in younger years and you will enjoy disease-free aging.

Sep
19
2015

Obesity Shortens Life

Of all the factors that definitely shorten life, obesity stands out like a giant. Let’s review a couple of facts regarding obesity:

  1. Americans who were born between 1966 and 1985 became obese at a much earlier age than their parents
  2. Obesity occurs at a younger age than in the past. 20% of people born between 1966 and 1985 were obese in their 20s.
  3. The longer you are obese, the higher the chance of getting seriously sick or dying prematurely from complications of associated diseases like diabetes, heart attacks, strokes, kidney disease, liver disease and cancer.
  4. Severely obese people live up to 20 years less than non-overweight people.
  5. Obesity causes about 300,000 deaths in the U.S. annually

Change of metabolism

Obesity leads to a change in metabolism, which is known as metabolic syndrome. The liver changes its metabolism slightly producing more triglycerides, LDL cholesterol and clotting factors, which increases the risk for heart attacks, strokes and pulmonary emboli. The pancreas produces more insulin, which gives rise to reactive hypoglycemia. This means that 2-3 hours after a meal you become hungry as your blood sugar declines from the extra insulin. You are craving a sugary drink, a donut or other starchy food (pizza, fries, bread etc.). Unfortunately these types of foods reinforce the metabolic syndrome: the liver changes the sugar into LDL cholesterol and triglycerides. Excess sugar will oxidize the LDL cholesterol, which causes atheromas (hardening of the arteries). Protein is being caramelized, which is called “advanced glycation end-products” or AGEs. This reference clearly explains how to counter this: increase your consumption of fish, legumes, vegetables, fruits, low-fat milk products and whole grains; also reduce your intake of solid fats, full-fat dairy products, fatty meats, and highly processed foods. There are other hormone changes that take place in obese people.

Death statistics due to obesity

In this study 849 autopsies were performed over 10 years, of which 32.3% were of obese persons. Leading causes of deaths in obese people were: malignancy (31.4%), infection (25.9%), ischemic heart disease (12.8%), pulmonary embolism (6.2%) and liver disease (2.9%). Table 2 of this link shows the causes of death in non-obese individuals as well: malignancy (32.5%), infection (23.8%), ischemic heart disease (10.4%), pulmonary embolism (2.9%) and liver disease (0.7%). The figures do not look all that different except that liver disease and pulmonary embolism are significantly more often the cause of death in obese patients than in normal weight patients. What you do not see in these figures is that obese people get these conditions at a much younger age as a result of complications from the associated diseases like diabetes, high blood pressure, cardiovascular disease, osteoarthritis, kidney disease and liver disease.

Diabetes

The metabolic changes with regard to the metabolic syndrome include insulin resistance.

As obesity worsens the balance is lost where the body can compensate and type 2 diabetes develops with increased blood sugar values and symptoms of diabetes. Surprisingly with regular exercise and changes in food intake (adopting a low glycemic index diet) this can be treated successfully. Usually this change is also associated with some weight loss, which helps to stabilize the metabolism. If nothing is done to to change diabetes, there is a high risk for heart attacks, strokes and subsequent secondary conditions like diabetic nephropathy, retinopathy, diabetic neuropathy and vascular complications.

Uncontrolled high blood pressure

High blood pressure is part of the metabolic syndrome. Unfortunately in obesity it is often difficult to control and may require several different antihypertensive medications in combination to control it. One way to quickly get the blood pressure under control is to make a concentrated effort to reduce a few pounds of weight; this can be achieved by cutting out refined carbs and sugar and starting an exercise program of walking and swimming.

Smoking

Smoking continues to remain a problem. Men as a group are now smoking less while women are increasing their smoking rates. Smoking causes various cancers, but also increases death rates from heart disease and strokes. In connection with obesity it is clear that the obese smoker has the highest risk of dying prematurely. This is depicted in this link based on the original Framingham study.

Disabilities and nursing homes

Obese people get disabled earlier, ending up in nursing homes. This poses a huge problem there for the staff. Back injuries and disabilities in the caregivers of nursing homes have increased significantly in the last few decades.

Osteoarthritis

80% of hip replacements and 90% of knee replacements are due to osteoarthritis. Obesity is the strongest modifiable risk factor that leads to osteoarthritis and subsequent surgery. There is a lot of morbidity and mortality associated with total knee and total hip surgeries. Part of this is the susceptibility to clot formation from the changes in metabolism associated with the metabolic syndrome. This often leads to pulmonary emboli and higher death rates following surgery when compared to surgery in people with normal weight.

Heart attacks and strokes

As there is an increase of the amount of heart attacks and strokes in overweight and obese people it is important to reduce your BMI when you realize that it is creeping up. Regular exercise along with a Mediterranean diet helps to improve this. Avoid processed foods that often have hidden sugar and refined carbs in them. Also cut out sugar. Use stevia, a natural sweetener, if you want to sweeten your food or drinks.

Nonalcoholic fatty liver disease (NAFLD)

In the past nonalcoholic fatty liver disease was rare. Now with the increase of obesity it is common. It can lead to liver cirrhosis with hepatic failure, a common cause of death. But after several years of liver cirrhosis, liver cancer may develop within the cirrhotic liver. Physicians saw this condition only rarely in decades past.

Kidney disease

With obesity there is a negative effect on the kidneys from the metabolic syndrome. Hyperinsulinism affects the capillaries of the filtration units, called glomeruli. They start to proliferate and undergo a form of degenerative change, called glomerulosclerosis. This decreases the filtration capacity of the glomeruli and the kidneys as a whole. After a few decades of this process kidney failure can set in. When an obese person develops diabetes, this will also have a negative effect on kidney function and accelerate the deterioration of kidney function. The end result is kidney failure, which requires dialysis or a kidney transplant.

Cancer and obesity

Chronic inflammation that is worsened by the metabolic syndrome leads to higher rates of various cancers. A prospective study of more than 900,000 US adults was conducted for 16 years. In 1982 when the study was started none of the participants had cancer. After 16 years 57,145 of the study participants had died of cancer. Those in this study who had a BMI of 40.0 or more had cancer death rates that were 52% higher for males and 62% higher for females when compared to normal weight men and women. It was noticeable that the digestive tract showed higher cancer rates in the obese: esophagus, liver, gallbladder, pancreas, colon and rectum; other more frequent cancers were kidney cancer, multiple myeloma and non-Hodgkin’s lymphoma. There were also trends of higher cancer death rates with regard to cancer of the stomach and prostate in men and breast cancer, uterine cancer, ovarian and cervical cancer in women. The authors concluded that due to the rising obesity rates in the US population cancer rates in men will soon reach the 14% level and in women the 20% level out of the total death rates.

Treating obesity

Treatment of obesity requires a multifaceted approach. I have discussed this in detail in this blog. Briefly, the diet of the obese person needs to be closely looked at. Sugar and starchy foods need to be eliminated. Low glycemic foods like vegetables, lean meat and salads should be encouraged. A regular exercise program needs to be instituted, starting with swimming and walking. Later a gradual transition into gym type activities could be contemplated.

Weight loss surgery has been successfully applied in some obese patients with a BMI that is greater than 30.0 up to a BMI of 39.9. In a 5-year follow up after LAP-band surgery no surgical complications were reported and the mean percentage weight loss was 15.9±12.4%.

Obesity Shortens Life

Obesity Shortens Life

Conclusion

Obesity is a condition that has been gradually developing since the 1980’s. When you look at the food intake changes rationally it is not surprising that this is happening. Sugar consumption, high-fructose corn syrup consumption and the consumption of processed food have to be cut down, if not cut out completely. You can forget shopping at the middle section of any grocery store, where all that processed food is located. Go to the vegetable section and buy a lot of food from there. Low fat dairy products, eggs, and low fat meats as well as salmon and other seafood are foods that are healthy. There is one problem though and that is the feeding of antibiotics to chickens, turkeys and beef cattle. This leads to superbugs and changes your gut flora. I suggest you buy organic meats. I eat organic food and have cut out wheat also as wheat underwent forced hybridization in the 1970’s. All of the wheat in the world now is this type of wheat that is too rich in gliadin, which causes leaky gut syndrome and autoimmune diseases. For this reason I avoid all wheat.

I see no reason why obese people could not gradually shed their pounds and regain their stable metabolism. Those with diabetes will be able to shed that diagnosis as they shed their pounds. The kidney and liver function will also stabilize when you shed enough pounds. The goal should first be to reach a BMI of 25.0 to 30.0, which is the overweight category. The next goal would be to aim for shedding even more pounds until you reach a BMI of fewer than 25.0. If you say this is too tough to do, I am saying: giving up is not an option. Cherish your health!

Sep
05
2015

Health Benefits Of Coconut Oil

Lately coconut oil has enjoyed a renaissance. A few years back it was still considered the saturated fat villain and was accused of causing heart attacks. The problem is that clinical trials could never proof that coconut oil would cause heart attacks or strokes; it actually showed the opposite: coconut oil prevented heart attacks! This is very interesting! This story is related to a powerful lobbying campaign of the soybean oil industry.

But perhaps more interesting is the fact that the medium chain fatty acids of coconut oil have a multitude of applications in the healthcare field so that your wrinkles and hair will benefit, your teeth will get less cavities and gum disease, you will have less infections, the immune system will be stronger and you will get less heart disease. But this is not all: coconut oil has been shown to specifically fight bacterial infections, viral infections, fungal infections and some parasitic infections. Anybody interested in 36 pounds of weight loss over 1 year? With coconut oil it is possible. There are definitely health benefits of coconut oil for you, hence the title of this blog.

In the following I will review this in more detail.

Properties of coconut oil

Coconut oil is derived from the white flesh of the coconut of the coconut palm tree. Cold-pressed coconut oil contains 92% saturated fats, 6%monounsaturated fats and 2% polyunsaturated fats. Olive oil in comparison contains 14% saturated fats, 77% monounsaturated fats and 9% polyunsaturated fats.

Tropical oils are coconut oil and palm kernel oil. These are the best sources of medium and short-chain fatty acids, which are fats ideal for cooking and frying food in a pan as both oils have a high smoking point. Coconut oil contains 64% of medium chain fatty aids (MCFA) while palm kernel oil has 58% of MCFA. Coconut oil is the one dietary oil that is least vulnerable to oxidation and formation of free radicals. This is the reason why it is safest for cooking or deep-frying. It has a melting point of 76 Fahrenheit (25 degrees Celsius). That means it is a white solid fat below that temperature and is a clear liquid oil above this temperature.

Coconut oil is composed of 48% lauric acid, 18% myristic acid, 7% capric acid and 0.5% caprylic acid. The coconut oil is a triglyceride, where three fatty acids are bound to a glycerol molecule. But when it gets in contact with our skin, the skin bacteria immediacy hydrolyze it into free fatty acids and glycerol. The same breakdown is happening in our mouth and gut by our own bacteria. The free fatty acids (FFA) are what give it the beneficial clinical effects. The FFA have antibacterial effects, antiviral effects, antifungal effects and antiparasitic effects. Specifically, lauric acid and monolaurin are the most anti-bacterial compounds of coconut oil. Coconut oil and palm kernel oil are the richest source of lauric acid; they contain almost 50% of lauric acid in their fats. In comparison, butter only contains 3% lauric acid.

Infections treated with coconut oil

Bacteria

Antibiotic resistant bacterial strains have become a serious problem in the past few years. Because of this it is important to know that the fatty acids derived from coconut oil have alternative antibiotic effects. Sinus infection can be treated by consuming coconut oil.

The CDC has reported that 75% of all cases of food poisoning are due to eating ground beef. This is due to resistant E.coli strains from beef that were fed antibiotics, so they would fatten up. The excuse of the Agro industry is that the farmers have to use antibiotics as the cattle in the crowded conditions of feedlots would otherwise get diseases. In 1993 seven hundred people got sick from eating contaminated Jack-in-the-Box hamburgers and at least 4 children died. Other common food poisoning bugs are salmonella strains. In 1994 a milk truck carrying milk that was contaminated with salmonella was shipped to an ice-cream factory in Minnesota. The contaminated ice cream was shipped to stores in several states and led to food poisoning of 224,000 people, the largest food poisoning outbreak in the US history. Giardia is another parasite that is common in India. Here is a study that showed how children with diarrhea due to giardia can be managed with coconut oil.

If you add all the cases of foodborne illnesses each year there are between 6.5 million to 81 million Americans who get sick and about 9,000 die as a result. One of the reasons of death from food poisoning is kidney disease and subsequent kidney failure; another common reason is blood poisoning.

So how does coconut oil fit into foodborne infections? When you eat 1 or two tablespoons of coconut oil three times with meals, the free fatty acids of coconut oil that are released in the gut get taken up into the blood stream and circulate in the body. If the free fatty acids encounter bacteria the medium chain fatty acids infiltrate the membrane of the bacterium and cause it to rupture. The same process happens in the gut to bacteria that do not belong there. Pathological E.coli, salmonella species and other pathological bacteria get eradicated in the same way I have just described. Other bacteria against which coconut oil is effective are H. pylori (the problem bug that causes gastric ulcers), Chlamydia pneumoniae, Haemophilus influenzae, Staphylococcus aureus (rodent study), Pseudomonas aeruginosa, Neisseria (the cause of gonorrhea) and many gram-positive bacteria (Ref.1, p. 75 and 76). I am afraid that most of these claims could not be verified by a PubMed search. PubMed had a reference regarding Salmonella and Pseudomonas aeruginosa in a mouse assay and both of these bacteria did not respond to coconut oil in various concentration.  However, Clostridium difficile, which is a problem bug with chronic diarrhea patients responded to coconut oil treatment.

Some women are plagued by frequent urinary infections. Coconut oil is a simple remedy that will treat these infections and when you eat coconut oil as a supplement or cook with it regularly you are having a good chance to eliminate them altogether.

When men get older they can be plagued by benign prostatic hypertrophy. This is a condition where the prostate is enlarged and squeezes the part of the urethra that travels through the prostate gland. The end result is that he has difficulties urinating. Urologists usually recommend a shaving off the prostatic tissue through a special cystoscopic procedure.

In a study on rats coconut oil was shown to decrease the prostatic weight as a result of treatment with coconut oil. In Ref.1 Dr. Fife stated that 1 to 2 tablespoons of coconut oil three times per day with meals would bring the swelling of the prostate gland down within only a few days and urination would be back to normal. However, I did a PubMed search for human data on benign prostatic hyperplasia and could not find a single literature quotation to confirm this.

Viruses

What about flu bugs? Dr. Fife cited a case of a woman who was just starting to come down with the flu (Ref.1). He recommended that she should take 2 to 3 tablespoons of coconut oil dissolved in lukewarm orange juice with every meal. On the first day her symptoms got worse as one often sees with seasonal infections. On the second day she expected to get worse again, but to her surprise the symptoms were starting to go away. By the end of the third day all of her symptoms had gone!

Other infectious agents that respond to coconut oil are: HIV, herpes-1 and 2, Cytomegalovirus, Epstein-Barr virus (the cause of mononucleosis), influenza virus (all strains), hepatitis C virus, Coxsackie B4 virus and others. A full list can be seen on p. 75 and 76 of Ref.1.

One of the chronic virus infections is hepatitis C. A person who has this condition is at a higher risk of developing liver cirrhosis and subsequently hepatocellular liver cancer. By using Coconut oil in the stage of chronic liver infections with hepatitis C virus the medium chain fatty acids do their trick of invading the outer membrane of the hepatitis C virus. The virus particles all rupture and release their genetic codes and cannot find another way of regenerating themselves. Within a few weeks and months the person can be completely hepatitis C free. Their energy comes back as the liver function returns to normal. From here the patient can rest assured that cirrhosis of the liver and liver cancer won’t develop.

Fungal infections

This is not the end of the surprising effects of coconut oil. Yeast bugs and other fungal infections respond very well to coconut oil. Candida albicans, the cause of gut infections, chronic vaginal infections and opportunistic infections in AIDS patients gets eradicated very similarly to the flu patient described above.

Athletes foot is a fungal infection between the toes that can go on for years with frequent flare ups, but it can be eliminated in just a few days by topical application of coconut oil. If you take it internally as well, it gets secreted through your sweat glands and eradicates the yeast bugs that way.

Parasites

Giardia lamblia is the cause for a common gut infection that is picked up by outdoor enthusiast, when they drink contaminated water. Cryptosporidium is another one of these parasites that won’t make cows sick, but when we consume drinking water that has not been fully sanitized, we get abdominal cramps and diarrhea. AIDS patients get seriously ill from this. Coconut oil comes to the rescue: it will do the same as with all the other bugs: destroy the envelope of the bugs with its MCFA’s, which destroys them. There is no anti-parasitic drug resistance that would develop. Several tapeworms respond very well to coconut oil treatment. However, some parasites like F. hepatica did not respond to coconut oil.

With respect to the transmission of malaria it was found that 2% Neem oil in coconut oil is an effective anti malarial mosquito repellant for 12 hours.

Dr. Fife gave an example of the building of the Panama Canal. The contractors found that the local indigenous Indians were the most reliable workers and never got sick. Yellow fever and malaria were the two diseases that plagued imported workers. According to Dr. Fife investigators found out that the local Indians consumed coconut oil regularly, which kept them slim and infection free including free of malaria and of yellow fever (Ref. 1, p. 94). I am afraid that a PubMed check for pertinent references regarding suppression of malaria and yellow fever could NOT be found.

Dental decay and coconut oil

Due to its broad-spectrum antibiotic properties coconut oil kills the germs that cause dental decay and gum disease, called periodontitis. You will keep the dentist less busy with regular coconut oil intake and save yourself a lot of dental bills.

Less heart attacks with coconut oil

There is a connection between poor dental hygiene, which leads to chronic Chlamydia pneumoniae infection and heart disease. Regular coconut oil consumption reduces heart attack rates and mortality of heart disease. Although the long-chain fatty acids of saturated fat and trans fat (hydrogenated vegetable oils) have been shown to cause hardening of the arteries (arteriosclerosis), this is NOT the case for medium-chain fatty acids from coconut oil. Research has shown that coconut oil is neutral with respect to blood cholesterol. Medium fatty acids are directly metabolized into energy by the liver, so they do not continue to circulate in the blood stream like other fats. In coconut consuming areas like Sri Lanka and Kerala, India very little heart disease was registered until the early 1980’s. Then only one of every 100,000 deaths was attributed to heart disease in Sri Lanka; and only 2.3 out of 1000 people in Kerala, India suffered from coronary artery disease in 1979. In contrast in the US about 333 out of 1000 Americans die of coronary heart disease every ear, that’s 1 in 3 people! Cardiovascular protection is further discussed here.

In this context it is interesting to read on this website that they believe coconut oil would cause heart attacks. Another study in Malaysian volunteers showed the opposite: no sign of changes in cholesterol, triglycerides or inflammatory markers. Many other studies have also shown that the medium chain fatty acids of coconut oil are neutral or beneficial in terms of cardiovascular disease.

Corn oil, safflower oil, grape seed oil, soybean oil, cottonseed oil, canola oil, peanut oil and even olive oil are increasing the risk for blood clots, which in turn is a risk for developing heart attacks and strokes. They are also omega-6 fatty acids that lead to inflammation and indirectly cause heart attacks and strokes. On the other hand, omega-3 fatty acids and the medium chain fatty acids of coconut oil reduce the risk of clot formation. This means there are only three safe oils: omega-3 fatty acids, coconut oil and olive oil when used non-heated and in combination with either omega-3 or with coconut oil. When combined with one or two of the other oils the blood clotting property of olive oil is neutralized.

Several mechanisms investigated in a rat model showed cholesterol-lowering effects of coconut oil. But when it comes to human studies, it was shown in premenopausal Philippine women that lipid profiles were also beneficially influenced by coconut oil consumption.

Improving the looks of your skin and hair

Coconut oil is protecting the skin against damage, heals and gives it a healthy and youthful appearance. It has been observed in Polynesians who are exposed to a lot of sun that they are protected from sunburns by applying coconut oil, and their skin remains youthful looking into an older age without the development of precancerous or cancerous skin conditions. They are eating coconut oil and put it onto their skin as a lotion. Coconut oil helps for extremely dry skin. At the same time it prevents bacterial, viral and fungal infections.

In one study mild to moderate atopic dermatitis skin rashes improved significantly with virgin coconut oil. Many cosmetics contain coconut oil and you may wonder how safe this is. A safety study has been performed regarding coconut oil based cosmetics and you can rest assured that it was found to be very safe.

Even hair can be treated with coconut oil. Dr. Fife quotes a New York hair stylist Amanda George who said: “I massage two teaspoons of warm coconut oil into my hair before bed, then wash it out in the morning.” Her hair is luxuriant, soft and shimmering (Ref. 1, p.135).

Alzheimer’s disease

Coconut oil has an inhibitory effect in terms of the development of Alzheimer’s. It seems that the medium chain fatty acids prevent aggregation of amyloid-β peptide and thus stop the further development in the direction of Alzheimer’s; coconut oil also helps reduce elevated LDL, insulin resistance and hypertension, which are all risk factors for Alzheimer’s disease.

Detoxing with coconut oil

When you first use coconut oil it can have a strong detoxification effect (medically termed “Herxheimer reaction”). It stimulates the immune system and helps the body to get rid of any stored toxins and germs. There can be a skin rash, sinus congestion, nausea, vomiting, fatigue and diarrhea. Not everybody experiences all of these symptoms, but one or the other. This can go on for a day or two, but sometimes it may take longer like several weeks. It may feel as if you are coming down with a flu, but this is not true: you are detoxifying and you will feel more energetic when this is behind you. Coconut oil is hypoallergenic, so it is very rare to have a true allergy to coconut oil. Most people do not experience the above described detoxification reaction.

Lose weight while eating coconut oil

Medium chain fatty acids (MCFA) from coconut oil have a different metabolism than long chain fatty acids (LCFA) like soybean oil, canola oil, safflower oil and others. Studies have shown that MCFA are burnt directly by the liver and lead to a higher body temperature production, called “thermogenic effect”. Various researchers found a two to threefold higher burning of calories in MCFA compared to LCFA. Over one year this translated into a weight loss of 36 pounds, if you replaced all of the LCFA fats in your diet with MCFA fats. Here is a clarification that coconut oil has medium chain fatty acids and is metabolized differently than animal fats. The weight loss happens like a “side effect” when you switch to cooking with coconut oil and supplementing with coconut oil. Here is a weight reduction study that was done in 20 healthy, obese Malay volunteers. They were all males.

Cancer

The role of coconut oil in cancer treatment is not yet investigated. Carbohydrate restriction is one way of starving tumor cells. It is conceivable that a ketogenic diet including coconut oil may be beneficial for cancer patients, but trials to this effect have not yet been done, which means we do not have the evidence for or against it. However, here is a study that showed that breast cancer patients had much less side-effects with chemotherapy when supplemented with coconut oil.

Health Benefits Of Coconut Oil

Health Benefits Of Coconut Oil

Conclusion

Coconut oil has experienced a renaissance in the last view years. It is now available in containers of various sizes as organic virgin coconut oil. Try a small container first and see how you react. In the beginning you may detox and feel like you have the flu for a few days. But later you will have more energy and you’ll gradually notice improvements of energy, of skin and hair. Your body will notice further improvements internally as the immune system functions better and you lose a few pounds. Your heart is pumping blood easier as there is less hardening of the arteries. Cook with coconut oil, as the smoking point for coconut oil is higher than olive oil, which means you are not eating oxidized or toxic oil. Use olive oil in your salad dressings. Throw away all the other oils, such as safflower oil, canola oil, sunflower seed oil, corn oil and soybean oil or grapeseed oil. These are largely omega-6 containing oils that cause heart attacks and strokes as they get oxidized and cause inflammation in the body through the arachidonic acid system.

Remember this: cook with coconut oil and use olive oil for salad dressings.

Read labels and make sure you are not buying the cheaper hydrogenated coconut oil with free radicals in it; opt for the cold pressed, virgin coconut oil, which is more expensive, but healthy.

In reviewing Dr. Fife’s “The Coconut Oil Miracle” I found that there are many experiential stories that may ultimately be true, if confirmed by trials or studies. I have attempted to find references, but could not find them for all topics mentioned above; be cautious regarding these gaps. I recommend that you keep an open mind, but at the same time stay critical. I think the overall evidence supports that coconut oil is a valuable nutrient that has many positive effects.

 

References

Ref.1: Bruce Fife, C.N., N.D.: “The Coconut Oil Miracle”, 5th edition,2013, Penguin Books, NY 10014

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Sep
13
2014

What To Watch Out For In Restaurant Foods

Recently I saw a flyer of a fast food chain restaurant entitled “Food Fact”. Interestingly you get the contents of a list of bakery items, warm breakfast items, burgers, sandwiches and wraps for lunch as well as yogurt parfaits and fruit cups.

I have to commend the restaurant chain to attempt to educate their customers by itemizing each item.  They have listed the serving size broken down into calories, total fat, saturated fat, trans fat, cholesterol, sugar, protein, dietary fiber, vitamin C, A, calcium and iron.

Based on my dietary habits I need to check this list.

No trans fat

Years ago I have given up on trans fats because trans fat contain free radicals that accelerate hardening of the arteritis. Granted , the percentage is low, but 20% come from natural meats and 80% from processed foods. It is the 80% from processed foods that I avoid. Here is another review that explain trans fats in more detail. This eliminates the baked sweet pieces like croissants, cookies, raisin bran muffins, oat fudge bars and even spinach feta wraps.

What To Watch Out For In Restaurant Foods

What To Watch Out For In Restaurant Foods

Total fat

Now we come to total fat. The content list shows me that calories in total and fat content in total are closely related. But you reach the peak when you swallowed a sausage, egg and cheddar breakfast sandwich. This alone accounts for 500 calories. This is also high in cholesterol and high in sodium, so not really on my list of desirable foods.

Sodium content

I am now getting concerned about my blood pressure as I follow the sodium content. Who would have thought that a spinach feta wrap has more than 800mg of sodium? And ham and a Swiss Panini have more than 1500 mg of sodium? Literally 50% of the food list would not be on my menu, if I want to limit my sodium intake to 400mg or less per helping. Especially the sandwiches are out!

Hidden sugar

So, now I am looking at a yoghurt for a light snack,  but suddenly the sugar column has sprung up from 1-2 mg of sugar content in simple sandwiches to 37 to 55 mg of sugar for honey creek yoghurt parfait to strawberry blueberry parfait. It is not the yoghurt, it’s not the fruit, it is extra sugar, honey or high-fructose corn syrup mixed in here. This is definitely not what I am going to choose.

Refined carbs

Although the carbs by weight do not appear too high on the list, it is the total of sugar and carbs and the fat that has been added, which add up very quickly to hefty calorie sums in all of the foods. I am shaking my head and I absolutely cannot find anything that is healthy and would merit being eaten by me.

Missing greens

I am missing vegetables and salads.  The only thing I see that I can eat is their classic oatmeal, which has 160 calories with a nut medley topping. I may add a decaf-coffee sweetened with my own stevia that I brought along and some cream (because that’s how I still like it having been raised in Germany).

Homemade food

Then I rush to the health food store and to the grocery store and load up on organic foods, meat, lettuce, broccoli, peppers, spinach, organic olive oil and balsamic vinegar. And, yes, a tub of plain goat yoghurt. Organic walnut halves are also on the list (quite expensive, I must say).

I suddenly realize that now I have all of the ingredients to never enter a restaurant again. I can prepare my own food and I can do it the way I want it, not how the food industry wants me to eat it.

If I ate the food industry’s way, the salt content would send my blood pressure through the roof and I would get hardening of the arteries within the shortest time (from refined sugar, starchy foods and trans fats).

I find the taste of home cooked meals superb. All of the flavors are there. Of course, I do not mind spending the extra money on the organic food, because the tastes are the way my grandmother’s food used to taste. I rarely add salt and my blood pressure is 105/65, so something must be going right.

I am thinking what would happen, if more people would do what I do: avoid restaurants, especially fast food places, pack your own lunch box with an organic salad and enjoy dinner at home. It can be simple, tasty, healthy, and economical. Nobody needs to be an accomplished chef to do that. Would there be pressure on the food industry to open up organic restaurants and offer alternatives to those who want to enjoy healthy, tasty foods ?  Or are the fast food places here to stay forever and ever?

Conclusion

I thought I go with you today to one of those fast food places that actually list their food content. Listing it does not really help when the whole list consists almost exclusively of foods that are having serious drawbacks, be it in the addition of too much sodium, fats, sugar or refined carbohydrates.

You do not want to get accelerated hardening of your arteries from too much fat, trans fat, sugar and starchy foods. You don’t want to get high blood pressure from too much salt day after day. You may want to rethink that processed foods are really lacking the nutrition that your body needs to function well and healthy. A lot of them are best to be thrown out. You need fresh, organic vegetables and lettuce, spinach, Swiss chard etc. Maybe you want a vegetable omelet for breakfast with egg white, spinach, peppers and Swiss chard? Take charge of your own life. Look after your own affairs. This includes what you do in your kitchen and what foods you consume.

More information on:

1. High blood pressure: http://nethealthbook.com/cardiovascular-disease/high-blood-pressure-hypertension/

2. Cardiovascular disease: http://nethealthbook.com/cardiovascular-disease/

Last edited Nov. 8, 2014

Jul
02
2014

Focus On Health Rather Than Disease

Not too long ago I came across a blog that summarized the “18 Biggest Problems with Modern Medicine”. Although this is a useful list, it occurred to me that these problems could be compressed into about 9 underlying themes. Below I am describing the same type of problems regarding modern medicine in a somewhat abbreviated fashion.

Points 1 to 4 below cover points 1 to 9 of the “18 Biggest Problems with Modern Medicine”:

1. The patient is seen as a complicated machine with parts that could break down. When there is a breakdown of the machinery, symptoms develop, which are quickly fixed with a patented medicine, but without really addressing the underlying problem. 

This type of approach soothes pain, but changes nothing for a chronic illness like MS. Nobody has all the answers to this complicated illness, but we know that it is an autoimmune disease. So it makes sense to avoid foods that could make the patient worse. This is exactly what Dr. Terry Wahls is describing in her YouTube video.

Also, vitamins and supplements for multiple sclerosis that support the immune system would be useful. Vitamin D3 in high doses, but monitoring blood levels by doing 25-hydroxy vitamin D blood tests from time to time would also be useful.

2. A holistic approach to building up health rather than fixing a clinical problem, which belongs to a disease, is not part of modern medicine.

In the past a stomach acid problem was treated with H-2 receptor antagonists like cimetidine or ranitidine. The newer proton pump inhibitors, like omeprazole were added and were supposed to be better in suppressing the acid formation. But they did nothing to cure the ulcer or gastritis problem. The problem often was that chronic stress allowed a bacterium, H.pylori to multiply in the stomach wall causing stomach acid and a burning sensation. This did respond to the antacid medications for a period of time, but came back when the medication was stopped. A simple over the counter licorice compound, called DGL or a simple mastic gum from the health food store can cure the helicobacter infection and cure your peptic ulcer disease without the need for the expensive patented H-2 receptor antagonists or proton pump inhibitors.

Focus On Health Rather Than Disease

Focus On Health Rather Than Disease

3. Everybody with the same disease is treated with the same medical treatment schedule, often agreed on by consensus expert panels. The body’s self-healing capacity or the placebo effect, which is an expression of the same natural healing response, is ignored.

Here is a study that was done on patients with irritable bowel syndrome (IBS) on placebo pills. Placebo pills were 24% more effective than the control group who took no pills in controlling symptoms of IBS. Why not utilize this in conventional medicine?

4. The disease is treated, not the patient; numbers from lab tests count, not clinical signs of the physical examination. What used to be called the “art of medicine” has been abandoned.

The art of medicine is important to establish a rapport with the patient, but also to pick up silent features during the examination that may otherwise be overlooked.

Points 10 to 18 of the“18 Biggest Problems with Modern Medicine” are covered by points 5 to 9 below:

5. Diet, lifestyle, hormone changes (due to chronic stress and older age) are all ignored. If there are the hormone changes of menopause or andropause, only synthetic hormones are given and only for a limited time not exceeding 5 years. Bioidentical hormone replacement invokes butterfly feelings in the physician’s stomach and must therefore be rejected. It’s almost a knee-jerk response. The reason for that is the fear that bioidentical hormones would have the same devastating side effects as the synthetic hormones. However, this is a fallacy, as a young person with fully functioning natural hormones will not come down with nefarious side effects of strokes, heart attacks or cancer.

This link to Dr. Lee’s website explains why bioidentical hormones fit the hormone receptors better than the synthetic concoctions.

6. The thought that the body may have been exposed to toxins (like heavy metals, xenoestrogens etc.) from the environment that are taken up and stored in the body like a sponge and should be detoxified from time to time is foreign thinking to modern medicine except for a small group of dedicated physicians and naturopaths who offer various forms of chelation therapy.

The TART trial has shown that there was a 18% reduction of heart attack rate in the group that received 40 chelation therapy treatments. Chelation therapy can easily be combined with traditional treatment methods, but mostly his option is ignored.

7. Similarly the idea that supplements and vitamins would be essential to support the body in the fight against free radicals that form inside the body every day is not something every doctor will feel comfortable in recommending.

In Ref. 1 (chapter 8) I have cited evidence from a clinical trial that multivitamins elongate telomeres by 5.1% and add 9.8 years of productive life in those who take multivitamins over a long period of time versus those who do not.

8. In the health care industry we are still working in a hierarchical system where the doctor is on top and the patient is on a lower level and dependent. In the future medical system the doctor and the patient are equal partners who try to solve a health problem as a team.

The doctor may have more experience in diagnosing, prescribing and monitoring health problems, but the patient is the one who owns the problem and is encouraged to comply with the prescribed treatment and to report back to the doctor, if there are new symptoms that may lead the doctor to new insights resulting in improving the treatment plan.

9. Big Pharma influences doctors to prescribe their patented medicinesNew drugs and old drugs are sold like the latest invention against the dreaded disease XYZ (you can fill in whatever the diagnosis is). But none of these drugs is effective against a hormone disbalance, stress, a lack of sleep, lack of exercise or malnutrition. The patient’s co-operation is needed to work on these issues.

I have explained in Ref.1 that the metabolic syndrome, which is responsible for much of our modern diseases (diabetes, heart attacks, arthritis, strokes, cancers, Alzheimer’s disease) can be overcome by a combination of steps: paying attention to our food intake, cutting out sugar and high glycemic starchy foods and excessive fats. Regular exercise will help you to build up and maintain muscle mass and at the same time to melt in excessive fat. Yoga, self-hypnosis, meditation and prayer can remedy stress. Bioidentical hormones can replace any hormone deficiencies. Detoxification, vitamins and supplements complete this program, which allows you to successfully age without disabilities. All these steps taken together allow your body to recover and find a new balance where drugs are rarely needed.

Conclusion:

The reason Medicare is so expensive is that life style issues are not often addressed. By only treating symptoms the underlying causes of an illness are not removed. This means that the illness will not be cured. Take for instance heart attacks. If you want to go down the road from angina to heart attack to bypass surgery or stents, you will soon run out of options. The next level of curative medicine approach is a heart transplant after heart attack number 4 or 5. Comprehensive medicine would approach this differently by paying attention to what you eat and motivate you to cut out starchy foods, wheat, and sugar. This would address obesity, which is a problem in many Western countries. You would engage in regular physical exercise. Stress would be overcome in yoga classes or self-hypnosis sessions. Bioidentical hormones would replace your missing hormones based on saliva hormone tests or blood test samples. The heart muscle that has a lot of testosterone receptors would respond to this. As mentioned above a series of chelation treatments to remove heavy metals could also be offered in this combined, comprehensive heart attack prevention program with a reduction of 18% of heart attacks. This all is available now, but regrettably few people make use of it.

References:

1. Dr. Ray Schilling: “A Survivor’s Guide to Successful Aging“, Amazon.com, 2014

Last edited July 3, 2014