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Not All Vitamins Prevent Cancer

Even in the recent past, vitamins were looked at as an essential weapon to prevent illness, however, a large study by the Cochrane Hepato-Biliary Group at the Centre for Clinical Intervention Research at Copenhagen University has come up with disappointing evidence.

A large evidence-based analysis was performed involving a population of 170,525 persons who were enrolled in randomized trials. They received a regimen of antioxidant supplementation that included beta-carotene, vitamin A, vitamin C, and vitamin E daily or on alternate days for 1 to 12 years, along with selenium every year for 2 to 4 years.
All trials reported the separate or combined incidence of cancer of the esophagus, colon, pancreas, stomach or the liver.
Results showed that beta-carotene alone, the most widely tested antioxidant for cancer prevention, did not have substantial cancer-fighting properties in gastrointestinal cancers. The devastating blow is the fact that beta-carotene in combination with vitamin A and vitamin C significantly increased mortality! Recent studies examining vitamin C show, that it can be an antioxidant, but it also can be a pro-oxidant (the less desirable quality). Trials involving selenium very clearly showed that it might have beneficial effects on the incidence of gastrointestinal cancers.
Following these news it would be a grave mistake to assume, that fruit and vegetables with their built-in antioxidants, micronutrients, dietary fiber and beneficial plant-chemicals have fallen off grace.

The truth is, that fruit and vegetables typically contain safe levels of vitamins. Most studies have reported that adequate intake of fruit and vegetables are indeed associated with a low incidence of cancer.
The study, however, clearly points out the pitfalls of vitamin supplementation.
-"The more the better" does not apply when it comes to taking vitamins.
-Antioxidants according to this study are not as beneficial for cancer prevention as was thought of in the past.
- Only vitamin C and selenium held up to the scrutiny of the evidence-based researchers with regard to having preventative effects regarding the above named gastrointestinal cancers.

The Lancet, Vol. 364,Number 9441,pg.1219-28, 02 October 2004

Weight Gain After Quitting Smoking A Myth

The fear of gaining weight after quitting to smoke tends to be a fear among a number of smokers, but a study presented at the annual congress of the European Respiratory Society in Glasgow in 2004 may very well put these fears to rest.
Dr. Audrey Lynas, a respiratory specialist at Sunderland Royal Hospital reported a study on 622 patients with chronic obstructive pulmonary disease (a late effect of smoking). The body mass index was not different from those who continued to smoke than those who were ex-smokers. Both groups had a BMI of 26, and five years down the line, they still haven't put on any weight, reported Dr. Lynas.

According to a 2002 survey in Britain, 30% of female smokers and 14% of male smokers said, that they would not try to quit, as they were afraid of gaining weight. Even patients with COPD (the previously mentioned chronic obstructive lung disease) may be influenced by this fear, even though it is crucial for them to quit in order to stop the progression of their lung disease.
It seems logical, that quitting the cigarette habit is not associated with weight gain. However, if nibbling becomes a substitute for smoking, frequent snacks lead to an overload of calories. Weight gain will be the consequence of the additional munching. Stop smoking is not the culprit for weight gain.

The Medical Post October 5, 2004, page 7

The Mediterranean Diet Definitely Not A Fad

Giacomo Castelvetro has first described healthy eating Mediterranean style in 1614. As an exiled Italian living in England, he tried to convince the English to eat a wider variety of fruit and vegetables and to prepare them in the same way he had eaten them in Italy. His attempt was a failure, however the same book has since been translated into English and published in 1989. In the meantime The Seven Countries Study by Ancel Keys in the 1950's showed that the population of Crete in Greece had very low rates of heart disease, of certain cancers and a very long life expectancy, despite generous consumption of fat in the form of olive oil.

Despite a wide variation between all the 15 countries bordering the Mediterranean Sea, there are common characteristics: an abundance of vegetables and fruit are consumed, along with nuts and legumes. Cereal products are largely whole grain. Olive oil is the principal fat source, and fish, seafoods and poultry are eaten in moderation. Red meat is consumed rarely. Cheese and yogurt may be eaten, depending on the region.
The first clinical evidence supporting the health benefits of the Mediterranean diet came from the Lyon Heart Study. Patients who had suffered a heart attack were either assigned the diet designed by the American Heart Association or a Mediterranean style diet. After a follow-up of 27 months, the group eating the Mediterranean diet had a reduction of heart attacks by 73 % and a decreased mortality by 70% compared to the other group.
When the various foods of the Mediterranean diet are analyzed, the reasons for the health benefits become very clear. The fats, which are consumed, are heart-healthy monounsaturated fats like olive oil or fats that contain omega-3 fatty acids, which are found in fish (tuna, salmon, trout, sardines) or from plant sources (walnuts and other tree nuts and flax seed).

As there is an emphasis on natural foods, the diet is extremely low in trans fatty acids (hydrogenated fats), which are known to increase the risk for cardiovascular disease. As more than 300g of vegetables per capita are consumed daily, the contents of antioxidants and other beneficial plant chemicals is much higher when compared to Western diets. There are many individual components of the Mediterranean diet that contribute to the reduction of disease and in particular of heart disease. It also is apparent, that it is not one single food or nutrient, but all the interactive effects of all the nutrients that are responsible for the health benefits.
The practical application does not mean deprivation and starvation, but a move away from processed fats (margarine), baked goods (donuts, muffins, pastries), and high saturated fat snacks and trans fats (chips, crackers, cookies, pies). Food choices move towards those of fresh fruits and vegetables, nuts, fish, and olive oil. Portions or servings have to be adequate to maintain a healthy weight.

Mediterranean food is not the heaping plate of pasta with an afterthought of vegetables, nor the super-size fast food pizza with pepperoni and cheese, but foods that incorporate the fresh food rather than the fast food. It entails a shift from large portions of red meat to smaller portions of fish, a transition from highly processed foods to ample helpings of dark green vegetables with a dose of olive oil. Low amounts of alcohol, especially red wine can make a meal enjoyable, which means one drink per day for women, and two drinks per day for men. And after dinner go for a walk! What Castelvetro tried to teach us in his writings back in 1614 is still true today.

Patient Care Canada, September 2004, Vol.15, No.9

New Remedy Zaps Colds

A new cold remedy has been developed in Alberta, and researchers from the University of Alberta in Calgary have concluded, that it is definitely doing the job.
Cold-FX is made of North American ginseng, and it cuts the chances of getting an upper respiratory tract infection (like coughs and sniffles) by 26 %. It cuts the chance of getting sick by 56 %. During a study, which has been released on October 5, 2004, 323 adults were tested. Researchers could also demonstrate that the disease fighting white blood cells and lymph cells increased in patients who took Cold-FX.
This study comes in time for winter, which thanks to the new developments does not have to be the season to be sneezing…

Flax Seed A Source Of Omega 3

Prevention has been gaining more momentum for public health as well as for the health conscious individual. Instead of looking at salvation from a slew of diseases like arteriosclerosis, high blood pressure, osteoporosis, Alzheimer's, and the complications from diabetes in the form of super pills, prevention looks a lot more promising.
Flax seed has been around for several thousand years, but it has been making a name for itself as part of healthy eating.

Its most important components are its fiber content, the alpha-linoleic acid, and the lignans. Eating flax seed helps to mop up cholesterol in the bowel, and studies have shown a drop in the "bad" LDL cholesterol levels. Duke University is publishing results that show flax seed to be helpful in blocking prostate cancer. A publication going back to August 2001 in the Archives of Ophthalmology point out the fact, that the omega-3 fatty acids, which are contained in flax seed, reduce the risk of macular degeneration. The same omega-3 fatty acids also have a favorable influence in the glucose response after a meal, a fact that is important for the prevention of diabetes.
It has to be mentioned at this point, that flax seed oil does not have all the benefits, as the fiber has been removed, and some of the benefits get lost as a result of the temperature used with processing. Also, just eating a spoon full of flax seeds will not be the answer, as flax seed is not fully used during digestion (the seeds are simply excreted in a bowel movement). To unlock the benefits it is best, to grind the seed.

A coffee mill does the job well enough, and freshly ground seeds are better than the pre-ground variety that has been sitting around in the bin of a store for some time. Two teaspoons of ground flax seed mixed with some yogurt and fruit makes for a good starter in the morning or an easy evening snack. A slice of flax seed bread does not give you the benefits; remember that heat during cooking or baking destroys the key components.
The nice part about flax seed is the fact, that it is inexpensive, plentiful, has no adverse side effects*, and it is the ounce of prevention which is readily available to you.

The Medical Post, October 12, 2004,page 13

* Comments (added Aug.28, 2005): Despite the Duke University study cited above there are disturbing news from a 14 year follow-up prospective study that has been confirmed by other studies showing that there are side-effects. This study showed that in males there is a 2-fold risk of developing invasive prostate cancer when flax seed was the supplement used. As flax seed contains alpha-linolenic acid(=ALA) and fish oil contains eicosapentaenoic acid (=EPA), there are striking differences of action that have not yet been defined in more detail. The same study showed that over 14 years EPA (when mixed with DHA) lowered the risk of getting invasive prostate cancer by 26%. Until it is known more how flax seed works, it likely is wiser to to take a molecularly distilled EPA/DHA supplement daily as this also reduces the cardiovascular risk, but at the same time prevents cancer.

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