Fight The Cold Or Flu With Mega Vitamin D3 Doses

Recently I came down with a cold, when I remembered that you can fight the cold or flu with mega vitamin D3 doses. The cold did not fit into my plans. I was three days before singing as a lead singer in a local church and I needed my voice. I felt a burning in the back of my throat and knew I was coming down with a cold. Next I felt congested in my nose and sinuses. I braced myself for the cold affecting my voice box and taking my voice away. But on the second day of the cold/flu I took 50,000 IU of vitamin D3. The following day the congestion was still confined to my nose and sinuses only. But it did not go any further down into my throat or chest.

Mega vitamin D3 doses saved my voice 

The following day was the church performance and everything went well. The Christmas songs created a festive atmosphere in the congregation. The psalm melody that my wife had composed was a welcome change from the normally stuffy psalm. And despite the feeling of an oncoming cold, my voice was still clear.

My cold did not progress

Since then I noticed some more mucous formation and I continued my dose of 50,000 vitamin D3 for a total of 3 doses. Through blood tests for vitamin D 3 levels I know that I am a slow absorber of vitamin D3 and normally need 10,000 IU daily to get into the normal range of 25-hydroxy vitamin D using a blood test. Now the cold symptoms settled down. There was nothing of the common laryngitis, where you sound scratchy. I also did not get a cough, which based on past experience, would have lingered on for weeks.

How vitamin D stimulates the immune system

Taking high doses of vitamin D3 releases cathelicidin and defensins.

These are polypeptides that have antibacterial and antiviral properties. The vitamin D antimicrobial pathway is described in detail here:

Vitamin D stimulates the immune system (B cells and T cells), which can suppress viral and bacterial infections. Here is another article that recommends the “vitamin D hammer” as the authors term the mega vitamin D3 therapy. Dr. Thornburg describes that an adult should treat a cold/flu within 24 to 36 hours after onset with 50,000 IU of vitamin D3 once daily for 3 days. He also lists pediatric doses. Following this treatment the patient resumes the previous vitamin D3 maintenance dose.

Opinion of conventional medicine

This approach is not conventional medicine. Here is a publication that states that Vitamin D, Vitamin C, Zinc, and Echinacea in combination can be useful in the treatment of the common cold.

But the section that describes the use of vitamin D seems to be very conservative. It does not even mention the importance of measuring the vitamin D blood levels. It is 25-hydroxy vitamin D which is what one needs to determine blood levels.

The normal level is considered to be 25-80 ng/mL. Many physicians say a level of 50-80 ng/mL is better. This blood test will measure the sum of vitamin D from oral vitamin D3 and from sun-induced vitamin D. This test also shows whether a person is a fast absorber or a slow absorber. What counts is that a person taking vitamin D3 gets the blood level into the therapeutic range.

Are there toxic levels of vitamin D?

Whenever the topic of mega dose vitamin D3 is mentioned, conventional medicine will warn that vitamin D toxicity could develop including kidney stones and “bone pain, drowsiness, continuous headaches, irregular heartbeat, loss of appetite, muscle and joint pain”.

In these cases of toxicity the researchers did not indicate what the level of 25-hydroxy vitamin D level was.

Other publications have established that the original recommended dose of vitamin D3 by the Food and Nutrition Board of 2000 IU per day was way too low. According to this publication based on many other papers 10,000 IU per day or more should be considered the new recommendation.

Dr. Schwalfenberg stated: “This is a 1-time 50, 000 IU dose of vitamin D3 or 10, 000 IU 3 times daily for 2 to 3 days. The results are dramatic, with complete resolution of symptoms in 48 to 72 hours. One-time doses of vitamin D at this level have been used safely and have never been shown to be toxic.”

The half-life of 25-hydroxy-vitamin D3 is 15.1 days. This means that the transient elevation of 25-hydroxy-vitamin D3 will last only 5 half-lives or 75.5 days. After that time (2 1/2 months) the mega dose taken over 3 days is eliminated.

Fight The Cold Or Flu With Mega Vitamin D3 Doses

Fight The Cold Or Flu With Mega Vitamin D3 Doses


Vitamin D3 has long recognition as a stimulant of the immune system. We now know that high doses of vitamin D3 release two polypeptides, cathelicidin and defensins. They have antibacterial and antiviral actions. Several physicians have developed a mega vitamin D3 approach when a cold or flu just starts to hit you. An adult should then take 50,000 IU of vitamin D3 daily for 3 days. In many cases it will cut the cold/flu short within 48 to 72 hours. Dr. Schwalfenberg said that “one-time doses of vitamin D at this level have been used safely and have never been shown to be toxic.”

Possible future clinical trial could verify effectiveness of mega vitamin D3

It would be desirable that the medical establishment conduct a clinical trial about the effectiveness of mega vitamin D3 use in colds/flus. Once the results are out, it would be loss of business for the pharmaceutical manufacturers.  Most of the cold-remedies would no longer be in high demand. For this reason it does not appear that it would be in the interest of Big Pharma or of organized medicine to organize such a clinical trial!

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