Aug
01
2008

Dietary Habits Help For Clear Skin

By | Nutrition, Skin Disorders

Acne can be a bothersome skin condition that is not only a source of embarrassment to adolescents but it can plague adults as well. A lot of foods have been associated with the annoying “zits” from chocolates to French fries or junk food. More research has come up in recent years, and some new facts have emerged. Clement Adebamowo of the Harvard School of Public Health in Boston studied 4,000 teenage boys and found a significant association between the intake of skim milk and the development of acne. There are numerous explanations for the dairy-acne connection. According to US doctors Alan Logan and Valori Treloar there are at least 4 precursors of the “acne hormone” dehydroepiandrosterone in milk from pregnant cows. Even though milk has a low glycemic index research has substantiated that milk based foods increase levels of insulin. Insulin in turn seems to be one of the major players when it comes to skin fat production (sebum). This leads to the blockage of skin follicles and the development of blackheads and acne. Lacks of dietary oxidants are also putting fuel on the fire of acne. Acne sufferers demonstrate lower antioxidant blood levels and as a result there is no ammunition to fight the skin inflammation of acne. Other foods contributing to this problem are omega-6 rich oils (sunflower, safflower and soybean).

Dietary Habits Help For Clear Skin

Dietary Habits Help For Clear Skin

Strong allies to fight the inflammatory process of acne are foods that are rich in omega-3 fatty acids such as salmon, mackerel or sardines. The intake of fruit and vegetables is beneficial (acne sufferers generally eat fewer fruits and vegetables than those who have a clear skin.) A trial by Robyn Smith of RMIT University in Melbourne, Australia showed that acne patients who were instructed to consume a low glycemic diet high in protein had significantly less acne lesions that their counterparts. This dietary approach reduces androgen levels. Beside a dietary approach there is still the need for dermatological input. Using both avenues acne sufferers will reap the most benefits.

More information about acne vulgaris: http://nethealthbook.com/dermatology-skin-disease/acne-vulgaris/

The Medical Post, June 24, 2008, page 19

Last edited November 4, 2014

Jul
01
2005

Diet Can Influence Acne

By | Nutrition, Skin Disorders

The old dermatological dogma that diet can play a role in the development of acne has been tossed back and forth. Some parties agree, others disagree. An old study by Fulton et al., which goes back to 1969, claims that patients who ate chocolate bars were compared to those who ate”pseudo-chocolate”, and no difference was found between the two groups. Both had the same amount of acne lesions. Critics of this poorly designed study however point out, that the” fake chocolate” contained just as much sugar and just as much trans fat as real chocolate. Trans fats are also known to contribute to inflammation, a condition that is present in acne.
In the meantime a 2002 study that was published in the Archives of Dermatology has taken a closer look at acne. Researchers took a look at islanders from Papua, New Guinea, and the Ache people of Paraguay. Both groups eat a non-Western low-glycemic diet. 1315 subjects were checked, and not a single case of acne was found. Even though this is merely an observational study, the results are impressive. Similar results have been reported in Okinawans, the South African Bantus, the Zulu and the Inuit. Even though these groups are continents apart, the common denominator is the same. Each group eats a non-Western diet. Another publication in 2005 in the Journal of the American Academy of Dermatology evaluated data from the Nurses Health Study II for a link between teenage acne and milk intake, and there was indeed a positive association. It may be that a milk allergy could be the explanation. Further evaluation is needed to pinpoint, which active compounds in milk are the culprits.

Diet Can Influence Acne

Diet Can Influence Acne

For now research points out that hyperinsulinemia, a metabolic condition stemming from an overload of highly refined and high glycemic carbohydrate foods, and its related hormonal cascade is the crucial link between the Western diet and acne. Other factors may emerge from investigating how milk consumption worsens acne.

More info on acne: http://nethealthbook.com/dermatology-skin-disease/acne-vulgaris/

Reference: The Medical Post, May 31, 2005, page 29

Last edited October 28, 2014

May
01
2004

Chronic Inflammation Causes Cancer, Heart Attacks And More

By | Anti-aging medicine, Arthritis, Cancer, Heart Disease, Obesity

When the Time Magazine devotes 7 full pages in the March 22, 2004 issue to the topic of inflammation as the source of most of the diseases of the Western World, you know that something important is happening in medicine. Christine Gorman and Alice Park have summarized some of the groundbreaking research of the past few years in this article. I will report about this article here, but also include direct links regarding some of the relevant research the authors have mentioned including some of the key links regarding the metabolic syndrome, which was not mentioned in the article.

Since the beginning of the obesity wave in North America it has become obvious that a cluster of diseases such as heart attacks, strokes, Alzheimer disease, cancer of the colon, multiple sclerosis, arthritis and others have also become more frequent. Dr. Paul Ridker, a cardiologist at Brigham and Women’s Hospital, was one of the pioneers of investigating inflammation as a possible cause and the common denominator of these diverse illnesses. He noticed that certain patients got heart attacks although their blood LDL cholesterol levels (the “bad” cholesterol) were normal. The theory at that time was that all patients who would develop heart attacks would come from a high-risk group of patients with elevated LDL cholesterol. The problem was that 50% of patients with heart attacks had normal LDL cholesterol levels. Dr. Ridker suspected that the C-reactive protein (CRP), which is found to be elevated in the blood of rheumatoid patients, would be somehow involved in the disease process of hardening of the arteries before a heart attack would occur. CRP is produced by the liver cells and by the lining cells of arteries in response to a general inflammatory reaction in the body. Examples of this would be rheumatoid arthritis patients and patients with autoimmune diseases, where CRP levels can be readily measured with a blood test. Dr. Ridker found that there was a very good correlation between the CRP level and the degree of inflammation as well as the risk for developing heart attacks and strokes. Further investigation by others confirmed that CRP levels were perhaps more important than LDL levels in predicting impending heart attacks. This is so, because CRP is the body’s substance in the blood stream that would be responsible for breaking up LDL containing deposits (plaques) in the walls of the arteries, which leads to heart attacks in the heart and to strokes in the brain.

Chronic Inflammation Causes Cancer, Heart Attacks And More

Chronic Inflammation Causes Cancer, Heart Attacks And More

Other investigators found that CRP was only one link in a complex chain of events that includes inflammatory substances (cytokines) from the fat cells as well as insulin and insulin-like growth factors from the metabolic syndrome. Leptins are also a factor as has been discussed under this link.
Dr. Steve Shoelsen from the Joslin Diabetes Center in Boston has developed a mouse model for the metabolic syndrome. These mice will produce huge amounts of inflammatory substances in their fatty tissue in response to any inflammatory process that is started in them. Anti-inflammatory drugs such as the statins or metformin, it is hoped, will be shown conclusively to dampen the inflammatory process and prevent heart attacks, strokes and diabetes as well as cancer, Alzheimers disease and arthritis. Heart disease has already been shown to be improved by anti-inflammatory drugs. Asthma is an inflammatory disease of the small bronchial tubes, which can be stabilized with the anti-inflammatory drug Avastin.

What can we do as consumers to prevent some of those life-threatening diseases? By reducing our weight through calorie restriction on a low-glycemic diet we can help to reduce the insulin-like hormone substances of the fatty tissue. Regular exercise of at least 30 minutes of a brisk walk daily or the equivalent of other sports activities will half our risk for colon cancer and many other cancers. A diet rich in fruits and vegetables as well as fish and fish oils will reduce the amount of free radicals in our system cutting down on the circulating inflammatory substances. This prolongs life, prevents all of the major diseases of modern civilization and leads to longevity as the study of the Okinawa diet has shown.

Based on an article in the Time Magazine, March 22, 2004 edition, page 54 to 60.

Here is a chapter on arteriosclerosis from the Net Health Book, which explains inflammatory changes of the arterial wall:

http://nethealthbook.com/cardiovascular-disease/heart-disease/atherosclerosis-the-missing-link-between-strokes-and-heart-attacks/

Last edited October 26, 2014

Feb
01
2004

Kidney Disease, Another Complication Of Metabolic Syndrome

By | Hormones, Nutrition, Obesity, Prevention

The metabolic syndrome is a new disease entity that is known to be associated with obesity. In order to make the diagnosis of metabolic syndrome at least 3 of the 5 components listed in the table under this link (hypertension, hypertriglyceridemia, low high-density lipoprotein cholesterol level or LDL cholesterol, high glucose level, abdominal obesity) have to be present.

Dr. Jing Chen and colleagues of Tulane University School of Medicine in New Orleans, La., published an analysis of the Third National Health and Nutrition Examination Survey in the Feb.3, 2004 edition of the Annals of Medicine. Patients with chronic kidney disease were identified in this study where 3, 4 or 5 of the metabolic syndrome criteria were positive. Two criteria for chronic kidney disease were measured:

1. if there was a significant reduction of the filtration capacity of the kidney.

2. if there was critical leakage of blood protein into the urine.

Kidney Disease, Another Complication Of Metabolic Syndrome

Kidney Disease, Another Complication Of Metabolic Syndrome

Depending on how advanced the metabolic syndrome was (all 5 criteria of metabolic syndrome positive versus only 3 or 4) there was a higher or lower risk of developing chronic kidney disease.

I have depicted the results of this study in bar graph form here. It shows clearly that chronic kidney damage occurs in a dose-response curve pattern depending on how severe the degree of the metabolic syndrome is.

Risk of developing kidney disease with various degrees of severity of the metabolic syndrome
 Kidney Disease, Another Complication Of Metabolic Syndrome1

With 5 factors of the metabolic syndrome present the risk to develop reduction in filtration capacity of the kidneys is almost 6-fold. This is 3-fold higher than in a person with a milder degree of metabolic syndrome where only two factors are present. Such a person would only have a 2-fold risk for developing chronic kidney damage (dark blue shaded bars in graph). A dipstick urine test can measure protein in urine, which is an alternative way to measure kidney damage due to the metabolic syndrome. These values followed a very similar dose-response curve (light blue shaded bars in graph). The authors of this study believe that the kidney damage inflicted by the metabolic syndrome is different from that caused by high blood pressure or by diabetes. Future studies will have to establish whether this type of kidney damage can be repaired by treating the metabolic syndrome with a low glycemic, calorie restricted diet coupled with exercise.

Based on an article published in: Ann Intern Med 2004:140:167-174.

Last edited December 8, 2012