• Close Diabetes Control Prolongs Life

    Close Diabetes Control Prolongs Life

      A 20-year study showed that close diabetes control prolongs life. A study divided 160 people with diabetes into two groups. The one group continued to get standard care. Yet the other group received a multi targeted, aggressive treatment protocol. As a result after 20 years the group with … [Read More...]

  • Healthy Oils For A Healthy Body

    Healthy Oils For A Healthy Body

    Healthy oils for a healthy body? Quite frequently the news are full of articles that want to inform you what fat or oil to eat. At the end the consumer often faces information overload and confusion. Here I am reviewing what we know about the various oils. 1. Coconut oil not as good as it was … [Read More...]

  • Young Heart Stem Cells Can Cure Old Hearts

    Young Heart Stem Cells Can Cure Old Hearts

    Young heart stem cells can cure old hearts in rats. This is what research at the Cedars-Sinai Heart Institute in Los Angeles found. You may not be that impressed, because this talks about rats and not humans. But this is a brand-new concept, so of course research of animal experiments is first. The … [Read More...]

  • Resveratrol Effective In Humans

    Resveratrol Effective In Humans

    Resveratrol has been labeled a powerful antioxidant; but is resveratrol effective in humans? Quack watch says: don’t buy into the hype that resveratrol is effective in humans. WebMD claims that there would not be enough medical evidence to say that the average person should supplement with … [Read More...]

  • Decreased Sperm Counts In Men

    Decreased Sperm Counts In Men

    What do decreased sperm counts in men tell us about our world? A recent study has shown that over the past 40 years males in many centers that tested for sperm counts have lost 50% of the sperm count that was normal in the 1970’s. The question is, what could have caused this? Nobody has definite … [Read More...]

May
01
2003

How Dangerous Is West Nile Virus…

West Nile Virus (WNV) is a flavivirus. Related flaviviruses cause Dengue fever and Yellow fever. The reason WNV has been on the news is that until 1990 the virus has not been observed in North America.

Up to that point it was only known to be present in Africa, India, the Middle East, southern France, the former Soviet Union and Indonesia. But since 1999 WNV has been spotted in dead crows in New York and recently also in Toronto/Ont. It is predicted that in 2003 the virus likely will reach the western parts of Canada. It has been spotted already in Washington late in 2002. It is mainly transmitted between birds and mosquitoes. Humans only get infected with WNV through infected mosquito bites. Only about 1% of all mosquitoes are infected with the WNV in endemic areas. The incubation time is 2 to 15 days after a mosquito bite.

Symptoms:

About 80% of people who get infected with West Nile Virus are without symptoms. About 19% will develop mild flu-like symptoms with muscle aches, a fever and a headache.

There may also be a skin rash and swollen lymph glands. After a week or less the symptoms disappear and the patient has recovered. In 1% of patients the infection can be severe with a high fever, a headache and a stiff neck due to meningitis.

 

How Dangerous Is West Nile Virus...

How Dangerous Is West Nile Virus…

Meningitis in this case is from an infection and inflammation of the lining of the spinal cord and brain with the WNV. In some more severe cases the virus can enter the brain tissue and cause a viral encephalitis with a high death rate. People over 50 years of age are particularly susceptible for developing the more severe forms, which often lead to death. Extreme muscle weakness and headaches are usually the presenting symptoms along with a high fever. They may turn unconscious, particularly with encephalitis, may stop breathing and may need to be intubated and put on a ventilator.

Diagnostic tests:

After clinicial suspicion the physician likely will either do a blood test or do a spinal puncture to remove a sample of spinal fluid for specific anti-WNV antibody testing.

Prevention:

The risk is very small as stated above as only 1% of mosquitoes are infected. Prevention consists in steps to prevent mosqitoes from breeding and to prevent them from stinging you. Instal screens on doors and windows.

Stay indoors at dawn, dusk and in the ealry evening. Avoid forested areas during the course of the day. Wear light colored, baggy clothes ( mosquitoes like dark clothes) with long sleeves and long pants. Your lawn should be mowed short to cut down on places for mosquitoes to hide. Still waters such as in clogged gutters, in saucers under plant pots, puddles of water under tarps or in old tires need to be eliminated. Bird feeders need to be flushed out with a garden hose every two to three days to interrupt the mosquito breeding cycle. Use a mosquito repellant with DEET in it (should not contain more than 30% for adults or 10% for children to avoid toxicity). Do not use DEET on children younger than 6 months old.

Treatment:

At the present time there is no treatment other than supportive therapy in hospital for sick patients. Remember that the main breeding cycle in nature for WNV is between birds and mosquitoes. As humans we need to watch that we stay “out of the loop” by following the above preventative measures.

Here are a few useful links regarding West Nile Virus:

Health Canada site on West Nile Virus

CDC site on West Nile Virus (question and answer style)

Last edited December 9, 2012

Apr
01
2003

Edible Vaccines From Lettuce, Tomatoes And Other Plants

Can vaccines be taken by mouth (orally)? Yes, we know this from the polio vaccine.

Can vaccines be produced by plants? This does not sound likely, but this is exactly what researchers have already achieved and what they are working on now. A group of researchers under Dr. Robert Rose from the University of Rochester in New York have been working on a number of vaccines with the help of genetic engineering.

The rationale is simple: in developing countries it can be difficult to keep vaccines refrigerated and to administer them by injection in a sterile manner through doctors and nurses. Also, the cost of production can be a major factor with regard to effectiveness of the vaccine on a population basis, if large parts of the community cannot afford the vaccine. For many vaccines to be effective more than 85% of the population have to be vaccinated. Newer research has shown that the protein envelope of a virus, which has a certain surface antigen associated with it, can be broken down into smaller subunits. According to a review article in The Medical Post ( March 4, 2003, page 29) Dr. Rose and his team have isolated the DNA sequence of the human papillomavirus (HPV) envelope in the early 1990’s. They were able to program potatoes to grow the protein subparticles that were immunologically active, but were not infective (no virus activity). In other words after genetic engineering the plant grows a vaccine, which can be safely consumed and the body mounts an immune response to this modified virus protein similar to the polio vaccine, but without a trace of virus.

Edible Vaccines From Lettuce, Tomatoes And Other Plants

Edible Vaccines From Lettuce, Tomatoes And Other Plants

As potatoes have to be cooked before consumption, some of the effectiveness of the vaccine gets lost. The researchers have since concentrated on other plants like apples, bananas, tomatoes and lettuce, which are eaten in the raw state. The various diseases that are being tested at the present time are: hepatitis B, respiratory syncytial virus (RSV), Norwalk virus, rotavirus and even the measles vaccine.

Dr. Charles Arntzen from the Arizona State University in Tempe, Arizona, has successfully applied the above technology to the production of plant vaccines against the Norwalk virus, the E.coli enterotoxin and hepatitis B in potatoes and tomatoes. He is taking this a step further as he is developing a technique of freeze-drying tomatoes containing the vaccine against the Norwalk virus, which allows the vaccine to be stored for long periods of time. When it is needed, it can be rehydrated and could also be delivered in pill form to vaccinate the population at risk at the time of an epidemic of enteritis the with Norwalk virus.

In summary, the new plant technology of vaccine production allows for much cheaper vaccine manufacturing. It eliminates the problems surrounding sterile injection techniques. The vaccine delivery by mouth allows for a much simpler distribution to a population at risk and can be done by lay persons. Also, a variety of vaccines will be able to be manufactured this way in future. The plant production is similar to the photocopying process where a template (the specific viral protein subparticle) is being copied by the plant. This allows for a number of vaccines against different strains of viruses to be programmed fairly quickly. It is an exciting new technique.

Here is a link to Influenza, which is one of the viral illnesses that can be significantly suppressed by vaccination.

Here is a link that explains the rationale of vaccinations and vaccination schedules.

Last edited October 25, 2014

Apr
01
2003

Menopause And Perimenopause In Women

In the February 19, 2003, issue of The Journal of the American Medical Association there was an extensive review of the topic of menopause and the time before and after menopause, called “perimenopause”.

The authors, Dr. Lori A. Bastian, from Duke University, and colleagues critically reviewed 1,246 articles on this topic and identified 16 studies that were accepted as being reliable regarding the review of this topic.

They were interested in finding menopause symptoms, signs and blood tests that would be reliable in terms of assessing whether a woman would be approaching menopause or would be in menopause. The result was that no single test or symptom was reliable, but that a number of tests and symptoms in combination were very helpful.

Menopause And Perimenopause In Women

Menopause And Perimenopause In Women

They measured reliability by “likelihood ratios (LRs)”. What this means is that any value above 1.0 is significant, but the higher the number, the more reliable and important is this fact or sign. I summarized the findings in table form below.

Results of a Review Study on Menopause in Women
(modifed according to Feb.19, 2003, issue of The Journal of the American Medical Association)
Findings:
Likelihood ratio (LR): Comments (by Dr. Ray Schilling):
self assessment of going through the transition 1.83 this is based on the effects of the changing hormones on the woman and how she feels it
is affecting her
symptoms of hot flashes 3.10 lack of estrogen from ovaries leads to a lability of the skin blood vessels with increased skin perfusion as well as stimulation of the sweat glands
night sweats 1.90
sleep pattern is changed and there is a loss of the day / night rhythm of skin perfusion
vaginal dryness 2.64 due to lack of estrogen
high follicle-stimulating
hormone levels
3.06 feedback from estrogen missing, which stimulates the hypothalamus of the brain to produce more
FSH hormone
low inhibin levels 2.05 this is a newer test, which is more specific than the FSH test and also has some importance in fertility work-ups
Self-assessment of perimenopausal status 0.25 this is not a reliable test as it is below 1.0. It was included to show how good the other tests are in comparison

The authors concluded that there is no need for blood tests for menopause diagnosis in a woman, if several points of the first 4 findings are positive (top part of the table).

Here is a link regarding menopause.

Last edited December 9, 2012

Apr
01
2003

Older Americans Need More Knowledge About High Blood Pressure

A telephone survey of 1,503 Americans age 50 or older was published recently by Dr. Brent Egan from the Medical University of South Carolina, Charleston, in the March 24, 2003 issue of the Archives of Internal Medicine. Although 94% had their blood pressure measured at least once in the past year, only 46% knew how much it was. Of all the patients who knew that they had a systolic blood pressure of 140 mm mercury or higher, 30% did not know that this was abnormal and was called “systolic hypertension (high blood pressure)”. 20% of patients with established high blood pressure did not take their medication or had on their own reduced the amount of medication they should have taken. In this group only about 1 in 5 complained that the cost of the medication would have been the reason for stopping the blood pressure pills.

Below are some more general results regarding this study in table form.

Apart from the remarks on the importance of education mentioned in the table I would like to stress how important it is for patients with high blood pressure to learn how to measure their own blood pressure at home.

Older Americans Need More Knowledge About High Blood Pressure

Older Americans Need More Knowledge About High Blood Pressure

The method of how to do this is not as important as the fact that you buy and use some kind of home blood pressure measuring device (either the conventional bood pressure cuff or the more expensive electronic device). You can measure and record your own blood pressure either daily or 3 to 4 times per week and bring this record with you to the doctor’s office with your next check-up. With this method you will gradually learn what life style factors bring your blood pressure up and how much medicine you need to take to control the blood pressure at all times. This will prevent major events such as heart attacks and strokes and preserve eye-sight and kidney function.
Here are the results of a telephone survey regarding older Americans and their understanding of high blood pressure (modified from March 24, 2003 issue of Archives of Internal Medicine).

Results of a telephone survey regarding older Americans and their understanding of high blood pressure
(modified from March 24, 2003 issue of Archives of Internal Medicine)
Findings:
Comments:
Older Americans have a higher rate of high blood pressure, particularly high systolic blood pressure This makes it even more important that they learn more about it and that they learn to measure
their blood pressure at home.
Older Americans are not as educated about high blood pressure than the younger generation Likely related to upbringing and different interests; in the past healthcare was left to physicians and nurses. Now we realize that only we can look after ourselves, the physicians
and nurses are “health consultants” whom we hire to advise us.
Older Americans prefer an integrated approach to the treatment of high blood pressure utilizing traditional, complementary and alternative treatments The authors concluded that a combination of education and holistic management strategies likely would work best. This needs to include new research on identifying the
most effective treatments. I would like to add that weight loss (in case of increased BMI), exercise and a zone-like diet would help complement traditional drug regimens
very effectively as well.

Here are various useful links regarding related topics.

Link regarding body mass index (BMI) .

Link regarding high blood pressure(hypertension)

Last edited December 9, 2012

Apr
01
2003

Flu Shots Prevent Heart Disease, Lung Disease, Strokes And Deaths

It has been known for some time that flu shots would be beneficial. But it was not known until now whether in larger field studies people who are 65 years or older would benefit significantly and to what degree from yearly influenza vaccinations (“flu shots”).

The April 3rd, 2003 issue of The New England Journal of Medicine published the answer to this question. Dr. Nichol from the University of Minnesota, Minneapolis, and his collegues have followed 140,055 patients of whom 55.5% were vaccinated against the flu in the 1998/1999 flu season.

They also followed 146,328 subjects during the 1999-2000 flu season of whom 59.7% were vaccinated against the flu. Below is a breakdown how they fared when compared to non-immunized controls (see table).

Flu Shots Prevent Heart Disease, Lung Disease, Strokes And Deaths

Flu Shots Prevent Heart Disease, Lung Disease, Strokes And Deaths

The examiners of this study concluded that high risk patients (asthma patients, patients with diabetes, cancer, elderly patients, arthritic patients and patients with high blood pressure) should have a yearly Flu vaccination.

Patients after Flu vaccinations. How did they do?
(based on 1998/99 and 1999/2000 flu seasons)
Complications: Observation:
Comments:
Heart disease: reduced 19% this included heart failure and heart attacks
Hospitalization for stroke: reduced 16% to 23% often hospitalization for stroke patients can be weeks and months, often resulting in other complications due to bacterial superinfections, falls or clots
Pneumonia and
influenza rate:
reduced
29% to 32%
this can lead to heart attacks and deaths from bacteria in the blood
Death rates: reduced 48% to 50% all of the deadly complications from getting the Flu remarkably reduced by Flu shots!

However, in my opinion anybody would benefit from regular Flu vaccinations as this boosts the immune system in general protecting against other infections and colds as well.

Here is a link to a chapter on the flu in Net Health Book.

Last edited October 25, 2014

Apr
01
2003

SARS (Severe Acute Respiratory Syndrome)

What is SARS? SARS is a new strain of an acute flu that leads to a high fever, a severe cough and an atypical pneumonia where the inflammation of the lung tissue caused by this new type of virus leads to a severe lung infiltration that can be detected with chest X-rays. Cases similar to SARS have been known to the medical profession for several decades under the name of “atypical viral pneumonia”.

Most viruses lead to a laryngotracheitis, affecting only the lining of the upper airways like the trachea and the voice box. However, SARS is not like this. It is a new strain of virus that goes right down into the lung tissue and leads to more severe breathing problems from secretions that plug the airsacs (alveoli) of the lungs. However, only about 3% to 4% of patients who get SARS actually die as explained in the links below (see CDC and WHO Internet sites). Here is a brief review explaining the evidence in the medical literature that is known at this time (April 2003). Since March 2003 it is known that SARS likely is transmitted by a small virus belonging into the same family of viruses like measles or mumps (the Paramyxoviridiae family of viruses). This WHO link explains this in more detail. However, Dr. Francis Allan Plummer from the National Microbiology Lab in Winnipeg/Canada has isolated a human metapneumo virus in six out of 8 specimens from high suspicion cases for SARS that were submitted to the Lab. It is at present not clear whether there are only one or perhaps two or three similar viruses that may work in concert in tricking the immune system not to mount an immune response in some susceptible persons whereas in the majority of patients the immune system produces enough antibodies to overcome the disease.

SARS (Severe Acute Respiratory Syndrome)

SARS (Severe Acute Respiratory Syndrome)

In a publication from the New England Journal of Medicine, which was released one month early on Apr.10,2003, the SARS working group noted that there has been a corona virus isolated from 18 SARS patients who died from this disease 10 to 14 days into it and that this was a new strain of virus, which likely originated from a single ill health care worker from the Guangdong Province in China. These researchers used genetic tests (reverse transcription- polymerized chain reaction), electron microscopic tests of cell cultures with throat swabs from infected SARS patients as well as immunological tests with group specific corona virus antibodies to pinpoint the cause of SARS.

The new name for this virus: Urbani SARS-associated coronavirus in honor of Dr. Carolo Urbani, a WHO investigator who died of SARS himself when he investigated the early epidemic in Asia.

There might be inborn (genetic) weaknesses in some patients. The National Institute of Health is developing a vaccine against the corona virus, which is thought to trigger SARS. At the present time the best therapy is isolation in a hospital for those who are very sick with a possible combination treatment with corticosteroids and antiviral antibiotics, which may be 70% effective in halting the disease. The most important point is prevention of further transmission by isolation procedures (quarantine). Hopefully there will be a vaccine available soon, which could possibly be incorporated into the Flu vaccine.

More information in Dr. Schilling’s Nethealthbook:  http://nethealthbook.com/infectious-disease/infectious-disease-infections/severe-acute-respiratory-syndrome/

Here is a link to the official CDC site about SARS

This link brings you to the World Health Organization site (WHO) where SARS is discussed.

Last edited October 25, 2014

Mar
01
2003

Testosterone For Male Menopause (Andropause)

At a recent continuing education meeting at the University of Calgary in Alberta/Canada, which was reported in the Jan. 14, 2003 edition of the Medical Post, Dr. Norman Wong (professor of medicine, biochemistry and molecular biology) reviewed the symptoms, investigations and treatment modalities available for men who experience andropause (the male equivalent of menopause). They are as follows (my summary in table form).

Here is a link to the ADAM questionnaire regarding andropause by Dr. Morley, a geriatrician at the St. Louis Unversity in Missouri. If you answer “yes” to question #1 and #7 (sexual dysfunction or lack of sex drive) or if you answer “yes” to any three of the other total of 10 questions, you should see your physician and ask for a testosterone blood test.

What should you know about testosterone blood tests? What counts is the free testosterone or bioavailable testosterone. Dr. Ronald Swerdloff, professor of internal medicine and endocrinology at the UCLA School of Medicine in Torrance, California, stated at this conference that testosterone production decreases with aging, but is actually also one of the causes of aging. Testosterone levels decrease 1% to 2% every year from the age of 30 onwards. However, the sex hormone binding protein (SHBP) can buffer these changes for a certain period of time, if the SHBP is binding less testosterone thus keeping the free or biologically available testosterone relatively stable for a number of decades or years. Often, however, the andropausal men who need testosterone replacement have high SHBP levels. Nobody knows why some men have problems earlier than others. So, if the free testosterone serum level is low (and the LH and FSH hormones are low or normal) this means that this man likely should have testosterone replacement therapy, if there are also clinical signs and symptoms of hormone deficiency.

Testosterone For Male Menopause (Andropause)

Testosterone For Male Menopause (Andropause)

As can be seen from this link to menopause in women , the pituitary hormones LH and FSH, which are also known as gonadotropins, should be high to indicate that the feedback mechanism between the estrogen (or in the male the testosterone) no longer suppresses the production of these gondotropins. The fact that this mechanism is lost in most older men shows that the hormone deficiency is likely much more profound than a simple deficiency, it may actually be indicative of the aging process of the hormone glands themsevles. The good news though is that with a simple testosterone patch this can be fixed. Your doctor can discuss this further with you.

Other possibilities are injections every 3 to 4 weeks with a Depot-testosterone hormone preparation or tablets. However, with the tablets the problem is that this will get metabolized in the liver and higher amounts of hormone are required to overcome the liver barrier. Liver cancer has been reported in a small percentage of men taking tablets for a long period of time (I do not like testosterone tablets for this reason). Prostate cancer is the other worry and regular PSA tests and prostate exams should be done by your doctor. As no controlled trials have been done yet regarding the safety of longterm testosterone replacement in andropausal men, Dr. Swerdloff recommended to replace only in the lower dose range to the point where the free testosterone serum values are just barely normalized and the clinical signs and symptoms disappear. Overtreatment should be avoided.

Andropause symptoms (male menopause)
Symptoms: Comments:
loss of sex drive (libido) testosterone, which is the male hormone produced by the testicles, is needed for a normal sex drive
erectile dysfunction
(impotence)
inability to have sustained erections
loss of male characteristics loss of male type hair distribution, deep voice, muscle mass etc.
fatigue and depression brain hormones dysbalanced from low testosterone levels
decrease in muscle mass, increase in fat mass lack of testosterone responsible for muscle loss and change in bone metabolism
oligospermia or azoospermia too little sperm count or no sperm present

Addendum Nov. 2, 2012: At the 19th Annual World Congress Anti-Aging and Aesthetic Medicine in Las Vegas (December 8-10, 2011) Dr. Abraham Morgentaler, a Harvard trained urologist explained that with bio-identical testosterone replacement there is no longer any concern about prostate or liver cancer with long-term use. It has been one of the “medical myths” that has been around.

See also link to andropause/male menopause from the Net Health Book.

Last edited December 9, 2012

Mar
01
2003

Hyperthermic Chemotherapy For Colon Cancer

When colon cancer comes back (Duke stage D cancer) there often are seedlings of cancer cells in the peritoneal cavity, which in the past made surgery impossible. However, at Montreal’s Maisonneuve-Rosemont Hospital the surgical oncologist, Dr. Pierre Dubé, is using a brand new technique that allows to do surgery even in these difficult cases. It has been known for some time that cancer cells are heat sensitive.

At the time of the surgery all of the visible cancer is removed, like with ovarian cancer, using a cytoreductive surgery approach. At the end all invisible cancer cells are treated with a combination chemotherapy fluid that is introduced into the abdominal cavity and that is heated in a controlled manner. Heat probes measure the temperature and make sure the fluid is heated to 44°C (111°F). Other experiments have shown that at this temperature chemotherapeutic agents enter into the cancer cells faster, as they had been rendered more fragile by the heat. The end result is an increase in survival by 2 to 2 1/2 years. This is a breakthrough because in the past conventional combination chemotherapy for this group of advanced colorectal cancer patients achieved a remission (meaning “response rate”) of 0%. Now with this new technique there is a remission rate of 30% to 50%. Hyperthermic chemotherapy for colon cancer was pioneered at the Gustave Roussy Institute in Paris where Dr.Dubé was introduced to this technique. This was reported in the Jan. 14, 2003 edition of The Medical Post (page 7). According to Dr.Dubé about 10% of all colorectal cancer patients will need this type of surgical approach and about up to 25% of patients who develop cancer spread into the abdominal cavity (peritoneal carcinomatosis) would be potential candidates for this treatment modality.

Hyperthermic Chemotherapy For Colon Cancer

Hyperthermic Chemotherapy For Colon Cancer

Comments: Recently there has been a paper intitled “Factors predicting survival after intraperitoneal hyperthermic chemotherapy with mitomycin C after cytoreductive surgery for patients with peritoneal carcinomatosis” by P.Shen et al. (Arch Surg – 01-JAN-2003; 138(1): 26-33). 109 patients with carcinomatosis of the abdominal cavity with different cancers were treated with cytoreductive surgery and hyperthermic chemotherapeutic solutions. With this procedure, after complete removal of gross cancerous disease, the 3-year survival rate achieved 68% versus 21% of those where gross cancer removal was not entirely possible.

Last edited October 25, 2014

Mar
01
2003

Garlic Component Effective Against Head Lice

The Jan. 21, 2003 edition of the Medical Post published an article about some Argentine research involving the active ingredient of garlic, allicin.

Dr. Juan Barboza and his collegues from the University of Cuyo in Mendoza started their research first with plant lice, as they had been approached by farmers to help them find a natural way to fight lice infestation of their crop .

Of the various chemical compounds in garlic it was the allicin compounds that were most effective in asphyxiating common pests, particularly plant lice. Subsequently they were experimenting with head lice formulations. Shortly after there was a severe outbreak of headlice infestation at the day care center of the university.

This was an opportunity for the researchers to test the efficiency of the new formulation of a mixture of allicin with a mint-scented cream. With only one application of this formulation there was a 96% reduction of the number of head lice within only 1 week!

Garlic Component Effective Against Head Lice

Garlic Component Effective Against Head Lice

Here is a link to other useful hints about head lice.

Last edited December 10, 2012

Mar
01
2003

Do Diet Drinks Make You More Hungry?

There were some articles recently that stated that diet drinks would make you hungry. However, they lacked proper controls. For this reason the gastroenterologist, Dr. Khursheed Jeejeebhoy, from the University of Toronto/Ontario designed a well controlled 10 week trial where several parameters were measured while patients were either snacking on diet drinks or on sugar containing soft drinks on top of their regular food intake, which was also closely monitored. The only requirement in the beginning of the study was that the subjects had to be overweight (body mass index of 27 to 28). Participants of the study were then divided randomly into subjects drinking soft drinks with either sugar or sugar substitutes. The drinks were blindly given, but meticulous records were kept of what was consumed. In addition the subjects were allowed to eat as many snacks as they liked with either sugar in it or sugar substitutes. Below  is a tabular summary of the findings.

The surprising findings were that the sugar group had an increased appetite and wanted to eat more and more. Sugar also raised the blood pressure significantly.

Do Diet Drinks Make You More Hungry...

Diet Drinks Make You More Hungry

The result was a significant weight gain during the 10 weeks of the trial while the other group (AS) had lost a significant amount of weight without any hunger pangs. The researchers also measured body fat versus muscle mass and found that the sugar group (SG) had gained fat mass without changing the muscle mass. On the other hand the atrtificail sweetener group (AG) had lost only fat mass, not muscle mass.

Dr. Jeejeebhoy concluded according to the article in The Medical Post (Jan.14, 2003 edition, page 27) that sugar in snacks and drinks should be kept to a minimum to prevent obesity from developing or getting worse. Patients with high blood pressure should avoid sugar as much as possible and stick to a low glycemic-index diet. Drinks should be diet drinks or fluids without sugar content. Do diet drinks make you more hungry? The answer is: “NO!”

Artificial Sweeteners And Weight Loss(10-Week Study)
Findings: Comments:
Additional Calories
from drinks per day:
AS: 250 Cal.       SG: 870 Cal.
total caloric intake over the 10 weeks: AS:decreasing steadily
SG:increasing
steadily
appetite sensation: AS:no appetite
complaints
SG:sugar stimulated
appetite
weight gain or loss: AS:significant weight loss SG:significant weight gain
activity level(exercise) no change in either groups (AS or SG)
blood pressure
AS:no change
SG:sugar increased
blood pressure significantly
AS=Artificial sweetener group SG=Sugar group

Comment: Not every diet drink is medically safe. Aspartame and Sodium cyclamate are brain excitotoxins. One of the safest alternatives to sugar is Stevia. Read this review about  sugar alternatives.

Last edited December 10, 2012