Mar
11
2023

Hormone Imbalance can Impact Health

Dr. Erika Schwartz spoke at the 30th Anti-Aging Conference in Las Vegas about “hormone imbalance can impact health”.  The talk was scheduled early in the morning on Dec. 10, 2022. She pointed out that when hormones are in balance people have energy, they sleep well, they have normal sexual functioning and they are fertile. But in contrast, when hormones are not in balance, their weight goes up, they suffer from fatigue, depression, and anxiety. In addition, they often have skin and hair changes, changes in menstrual regularity, acne, infertility and decrease in libido. Finally, they may have problems in building muscle mass, women develop vaginal dryness and men erectile dysfunction. However, people also can develop autoimmune conditions and various cancers.

Symptoms of hormone imbalance at various ages

Teens

Most importantly, acne is an embarrassing, but common symptom. Depression, PMS, mood swings and headaches are also very common. By the same token, weight gain occurs frequently from faulty diets (fast food, lack of vegetables and fruit and sugary soda drinks).

The twenties and thirties

The birth control pill interferes with the normal function of LH and FSH resulting in lack of ovulation and infertility. Other symptoms are bloating, constipation, weight changes, libido changes and postpartum depression.

The forties and fifties

Mood changes and irritability, weight problems, menstrual changes, and changes in sexual desire are typical for this age group.

The sixties and over

Hot flashes are common in this age group, but they can start in women from the age of 50 onwards. Other symptoms are night sweats, insomnia, skin and muscle changes. Many diseases of the aging occur like diabetes, arthritis, cardiovascular disease, dementia, degenerative and autoimmune diseases.

Diagnosis of hormone imbalance

The doctor takes a detailed history about exposure to environmental pollutants, the birth control pill in women and medications. In addition, the doctor wants to know whether the patient consumed meat from animals that were treated with antibiotics. Next the physician inquires about physical changes, symptoms of hirsutism, menstrual

irregularities and infertility. There are three steps to diagnosing hormone imbalances:

  1. Listen to the patient and inquire about the subjects just mentioned.
  2. Order extensive laboratory tests including hormone levels.
  3. Review all of the medications and supplements the patient is taking.

How do hormone imbalances affect our bodies? They affect our mental health, our sleep, brain function, libido, energy, weight, digestion (leaky gut), joints and the immune system.

Two clinical examples about hormone imbalances

Dr. Schwartz gave two clinical examples showing how correction of hormone imbalances led to normalization of the hormone imbalance.

Example 1

A 17-year-old female complained about acne in her face, had no periods, was fatigued and had migraine headaches. She was in senior high school and wanted to look and feel better before graduation. Her periods started at age 12, but were irregular. Her physician started her on the birth control pill at age 14. Within one year she stopped having any periods and also started getting hyperpigmentation in her face. Dr. Schwartz noted that she had no allergies and that she did not take any supplements. She took Estarylla (ethinyl estradiol/ norgestimate), a BCP formulation and Excedrin for migraines. Her ferritin level was 12 (11 to 307 micrograms per liter is normal for women). TSH was 5.16 (normal now 0.5-2.5). This meant she was borderline iron deficient and also mildly hypothyroid.

Diagnosis and treatment plan

Dr. Schwartz diagnosed a hormone imbalance. The treatment schedule consisted of stopping the BCP, start a low dose 30 mg NP thyroid in the morning. In addition, the doctor prescribed adrenal support pills and low-dose iron pills with vitamin C. The doctor also addressed lifestyle and self-awareness issues with the patient. 4 months later she was seen again and had regular periods, no more migraines and she felt more energy. The face pigmentation was gone and she felt great.

Example 2

A 42-year-old woman presented to Dr. Schwartz with psoriatic arthritis, weight gain, problems sleeping, brain fog and irregular periods. Her last menstrual period was 6 months ago. Her doctor had recently placed her on a statin drug and put her on the BCP Mirena. This is a progestagen releasing IUD placed in the uterine cavity, which was given to her in an attempt to regulate her periods. She was divorced and a mother of 3 children. At work she was a business partner in a high stress law firm. Personally, she was trying to date, but has been unsuccessful so far. She would like to lose weight and gain more energy. What she was hoping for was that her doctor address her overall health.

Medication and blood tests

She did not have any allergies. Her medications consisted of Rosuvastatin 10 mg daily and Mirena for the last year. As supplements she took Turmeric. Blood tests showed that her hemoglobin A1C was 5.7, the vitamin D blood level was 17 ng/mL (very low). The TSH level measured 1.29 (in the normal range). Estradiol blood level was in the lower range, progesterone level the same. Finally, her testosterone level was low as well. The other blood tests were all normal.

Diagnosis for this patient and treatment plan

Dr. Schwartz diagnosed hormone imbalance due to natural and environmental factors.

She ordered Mirena to be removed and to stop Rosuvastatin. Instead, she started the patient on vitamin ADK ( a mix of vitamin A, vitamin D and vitamin K)– 5000 IU daily. She also started her on Omega3 1000mg daily. In addition, she discussed a well-balanced diet, regular exercise and sleep issues (7-8 hours every night) with her.

Hormone replacements

As blood tests showed a low estradiol level, she started her on Estrogel, a form of estrogen. She also started her on progesterone tablets (Prometrium) 100 mg at bedtime as well. This keeps progesterone and estrogens balanced. As her testosterone was on the low side, she started her on Testosterone cypionate 100 mg/ml (0.4 cc per injection) intramuscularly once a month. Dr. Schwartz also started adrenal support, 2 capsules in the morning. Further she was told to start 3 capsules of NMN (Nicotinamide Mononucleotide Supplements) daily and 5 units of Semaglutide subcutaneously weekly. The latter medication helps the pancreas to release the right amount of insulin when blood sugar levels are high.

Follow-up at 6 months

The doctor reassessed he patient after 6 months. She had developed increased self-awareness. She lost 30 pounds and she slept for 7.5 hours most nights. Her energy level has increased and she improved her dietary choices. She had started regular work-outs. Overall she was now happier at work and at home with her children. She feels now more like an age of 25, and she has been starting to date.

General remarks about hormone imbalance

When hormones are in balance, we are healthy. Hormones can get out of balance at any age; the examples above involved 17 and 42 year old patients. Keep in mind that it is impossible to have optimal health without balanced hormones. Dr. Schwartz said that the more pieces of the puzzle you address, the more likely you are going to truly help improve quality and quantity of life. Lifestyle factors that must be addressed are:

  • Diet
  • Exercise
  • Stress Management
  • Sleep
  • Breathing
  • Mitochondrial and cellular integrity
Hormone Imbalance can Impact Health

Hormone Imbalance can Impact Health

Conclusion

Hormone imbalances occur frequently when our lifestyle factors are slipping. Often untoward side effects of medication are also contributing to the hormone imbalance. The holistic doctor takes a thorough history, examines and takes blood tests including key hormone tests. When imbalances of hormones are detected, this has to be addressed with supplements and hormone replacements. At the end the hormones balance each other and the patients’ abnormal symptoms disappear. It only takes a few weeks before the patient will feel normal again.

Aug
24
2013

Pimples And Acne Can Be Caused By Food

This article is about “pimples and acne can be caused by food”.For a long time nobody knew why teenagers get acne. But many assumed that it would come from hormonal changes as teenagers grow up. But why then are there some ethnic regions in the world where teenagers do not get acne? In this blog I will present the background that shows that wheat, sugar and dairy products are the culprits. People in regions of our planet where acne does not exist do not eat these foods.

Regions where acne does not exist

1. The Kitivan Islanders of Papua New Guinea have no cases of acne in teenagers. They adhere to the old hunter/gatherer diet of no sugar, no alcohol, no wheat and no grains. Instead they eat root vegetables such as sweet potato, yam, taro, tapioca; fruit like papaya, pineapple, banana, mango, watermelon, guava and pumpkin; and also vegetables, coconuts and fish.

2. African Bantus and Zulus: These original African warriors eat a low glycemic diet with no wheat, no milk and no refined sugar or starches. Their teenagers and young adult do not have acne, if they stick to the original tribal diet.

Further regions without acne

3. Aché hunter/gatherers of Paraguay: a study by researchers from the Colorado State University in 2002 showed that sugar, wheat and other high-glycemic foods were missing in the diet of these native tribes. As a result they have no acne when they consume this type of diet, which is very similar to the Kitivan Islanders of Papua New Guinea.

4. Japan’s Okinawans when sticking to their original diet before 1970 had clear complexion and no pimples (acne). But as this link shows the McDonald’s and other fast foods with too much salt, too much sugar, wheat, deep fried and convenience foods entered the scene after 1970 and the acne rate went up to the American level.

More regions without acne

5. The natives of the Purus Valley in Brazil: A dermatological examination of 9955 school children age 6 to 16 showed an acne incidence of only 2.7%. In contrast in Westernized countries the rate of acne is 60 to 80%. The diet in this region is again similar to the other groups already mentioned above.

6. Canadian Inuit before 1950 did not consume dairy products and were acne free. Since then, there has been a steady increase of dairy products, soda, beef, and processed foods.

How acne develops

The medical term for pimples or acne is “acne vulgaris”. For years it has been postulated that hormones and medication can cause acne. According to Ref.1 there are several steps that work together in causing acne. The hair follicle and sebaceous gland work as one unit. Male hormones, called androgens play an important role in the development of acne, both in males and females. Males produce testosterone not only in testicles, but also in the skin itself. An enzyme, 5-alpha-reductase, converts it into the much more active metabolite dihydrotestosterone. In individuals with hypersensitive receptors in the sebaceous gland this causes blockage in the sebaceous gland ducts. At the same time, it stimulates the sebaceous gland oil production leading to the formation of a keratotic plug. White heads and black heads are formed this way.

Factors leading to inflammatory substances

Factors that contribute to inflammatory substances are sugar, wheat and starch intake causing insulin release. This stimulates IGF-1 receptors in the skin, which causes growth of the subcutaneous skin layers, which is pushing up from the layer below the skin, kinking the sebaceous gland duct and causing acne pustules (pimples) to form. A skin bacterium, called Propionibacterium acnes (P. acnes), is getting trapped in the pimple causing a local skin infection, which in turn can cause acne cysts and furuncles, particularly in males where there is a family history of acne. High cortisol levels from stress can also be a contributing factor in causing acne. Today’s teenagers are exposed to a lot of stresses from exams, competitive sports and peer pressures.

Polycystic ovary syndrome

Females with PCOS (polycystic ovary syndrome) have higher androgen production from ovarian cysts, which results in acne as well.

Both male and female teenagers experience an androgen surge when puberty sets in. If the teenager avoids the additional insulin response, which comes from eating sugar, starch, grain and particularly from consuming wheat and wheat products, the plugging up of skin pores will not occur, meaning these teenagers will be acne free.

Milk sensitivity

Some teenagers are also sensitive to milk protein from milk and milk products. In sensitive people whey protein allergy causes the same insulin/skin IGF-1 response described above. This leads to blocking of skin pores. If there is no blockage in the hair follicle, the P. acnes bacteria will stay on the surface of the skin (these bacteria are part of the normal skin flora) and the sebaceous gland secretions flow unimpededly to the surface of the skin keeping it naturally lubricated. These observations are further confirmed by a study from Malaysia in 2012 showing that a high glycemic load diet with milk and ice cream caused worsening of acne in teenagers of both sexes.

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Treating acne correctly

A)   Conventional acne treatment

Big Pharma has a firm hand in the treatment of acne;  they are supporting symptomatic treatment of acne rather than treating the cause. There are surface treatment modalities that open the skin pores: peeling agents such as benzoyl peroxide. General practitioners often treat the infection with antibiotic pills (tetracycline or erythromycin), but this is not treating the cause, only the super infection that comes from the plugged-up skin pores (stasis of sebaceous gland secretions). Another approach is topical application of antibiotic and peeling agent in combination (1% clindamycin and 5% benzoyl peroxide gel), which the patient applies twice daily (Ref.2). Resistant cases, usually the ones who have a family history of severe acne, have been treated by a skin specialist who has a special license to treat with isotretinoin (Accutane), a vitamin A derivative. It works in many cases, but it often has serious side effects.

Side effects of Accutane

These include skin dryness, eye dryness, muscle and bone pains, headaches and liver enzyme abnormalities. There can also be an instability of mood including depression and causing birth defects in the fetus of a pregnant woman (Ref. 3). In 2009 the manufacturer stopped distributing the drug in the US, because of too many lawsuits regarding damages from the drug.

I am not saying you should ever take this toxic medication. What I am saying is that treating symptoms, but not the cause has led to peculiar drug manufacturing. Physicians use this drug now to treat brain cancer and pancreatic cancer.

B)   Dietary approach to treat acne

There has been a renewed interest in the last 40 years to sort out the connection between dietary factors and acne. The most straightforward treatment in my opinion is to modify what you eat.

A clinical trial from the University of Melbourne in 2007 showed that a low-glycemic diet reduced the acne lesions by 22% compared to a control group.

Two factors are clear: a low-glycemic diet produces fewer pimples, the stricter the patient applies a low-glycemic diet, the more effective the treatment is. Up to 50% reduction in acne lesions were observed among patients with acne who adhered to a strict low-glycemic index diet in just 12 weeks. There is also evidence that milk and other dairy products can contribute to acne, which works through the same mechanism of IGF-1 stimulation mentioned above.

Milk and skim milk can cause acne

A US study from Boston showed a 22% increase in acne lesions with total milk consumption and increase of 44% after skim milk consumption.

Omega-3-fatty acid supplementation is useful for inflammatory acne in about 2/3 of the cases as this study showed. Here is an image of a patient from this study who benefitted from omega-3 supplementation. The baseline image is seen with inflammatory acne lesions on his cheek. Only 12 weeks after taking 3 Grams of omega-3 supplementation daily his face looked much improved.

Conclusion

There is a lesson we learn from the analysis of the regions in the world where acne does not exist. Cutting out wheat, wheat products, grains, sugar, milk and milk products leads to amazing results regarding acne prevention. This leads to improvements of patients who suffer from acne. We have been lulled into believing that medical science will give us a magic pill to solve our complexion problems. I mentioned that one of the “magic pills” (isotretinoin) is so toxic that physicians now use it for cancer treatments. All along we allowed the food industry to destroy our complexion. They did so by inducing an insulin and IGF-1 response that plugged up our skin pores. We can open them up by eliminating certain foods. They are wheat and wheat products, sugar, high-glycemic foods as well as dairy products.

More information on acne: http://nethealthbook.com/dermatology-skin-disease/acne-vulgaris/

References

  1. Rakel: Integrative Medicine, 3rd ed., Saunders 2012. Chapter 73 : Acne Vulgaris and Acne Rosacea, by Sean H. Zager, MD
  2. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 7th ed., © 2009 Churchill Livingstone.
  3. Cleveland Clinic: Current Clinical Medicine, 2nd ed., © 2010 Saunders.

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Aug
01
2008

Dietary Habits Help For Clear Skin

Acne can be a bothersome skin condition that is not only a source of embarrassment to adolescents but it can plague adults as well. A lot of foods have been associated with the annoying “zits” from chocolates to French fries or junk food. More research has come up in recent years, and some new facts have emerged. Clement Adebamowo of the Harvard School of Public Health in Boston studied 4,000 teenage boys and found a significant association between the intake of skim milk and the development of acne. There are numerous explanations for the dairy-acne connection. According to US doctors Alan Logan and Valori Treloar there are at least 4 precursors of the “acne hormone” dehydroepiandrosterone in milk from pregnant cows. Even though milk has a low glycemic index research has substantiated that milk based foods increase levels of insulin. Insulin in turn seems to be one of the major players when it comes to skin fat production (sebum). This leads to the blockage of skin follicles and the development of blackheads and acne. Lacks of dietary oxidants are also putting fuel on the fire of acne. Acne sufferers demonstrate lower antioxidant blood levels and as a result there is no ammunition to fight the skin inflammation of acne. Other foods contributing to this problem are omega-6 rich oils (sunflower, safflower and soybean).

Dietary Habits Help For Clear Skin

Dietary Habits Help For Clear Skin

Strong allies to fight the inflammatory process of acne are foods that are rich in omega-3 fatty acids such as salmon, mackerel or sardines. The intake of fruit and vegetables is beneficial (acne sufferers generally eat fewer fruits and vegetables than those who have a clear skin.) A trial by Robyn Smith of RMIT University in Melbourne, Australia showed that acne patients who were instructed to consume a low glycemic diet high in protein had significantly less acne lesions that their counterparts. This dietary approach reduces androgen levels. Beside a dietary approach there is still the need for dermatological input. Using both avenues acne sufferers will reap the most benefits.

More information about acne vulgaris: http://nethealthbook.com/dermatology-skin-disease/acne-vulgaris/

The Medical Post, June 24, 2008, page 19

Last edited November 4, 2014

Jul
01
2005

Diet Can Influence Acne

The old dermatological dogma that diet can play a role in the development of acne has been tossed back and forth. Some parties agree, others disagree. An old study by Fulton et al., which goes back to 1969, claims that patients who ate chocolate bars were compared to those who ate”pseudo-chocolate”, and no difference was found between the two groups. Both had the same amount of acne lesions. Critics of this poorly designed study however point out, that the” fake chocolate” contained just as much sugar and just as much trans fat as real chocolate. Trans fats are also known to contribute to inflammation, a condition that is present in acne.
In the meantime a 2002 study that was published in the Archives of Dermatology has taken a closer look at acne. Researchers took a look at islanders from Papua, New Guinea, and the Ache people of Paraguay. Both groups eat a non-Western low-glycemic diet. 1315 subjects were checked, and not a single case of acne was found. Even though this is merely an observational study, the results are impressive. Similar results have been reported in Okinawans, the South African Bantus, the Zulu and the Inuit. Even though these groups are continents apart, the common denominator is the same. Each group eats a non-Western diet. Another publication in 2005 in the Journal of the American Academy of Dermatology evaluated data from the Nurses Health Study II for a link between teenage acne and milk intake, and there was indeed a positive association. It may be that a milk allergy could be the explanation. Further evaluation is needed to pinpoint, which active compounds in milk are the culprits.

Diet Can Influence Acne

Diet Can Influence Acne

For now research points out that hyperinsulinemia, a metabolic condition stemming from an overload of highly refined and high glycemic carbohydrate foods, and its related hormonal cascade is the crucial link between the Western diet and acne. Other factors may emerge from investigating how milk consumption worsens acne.

More info on acne: http://nethealthbook.com/dermatology-skin-disease/acne-vulgaris/

Reference: The Medical Post, May 31, 2005, page 29

Last edited October 28, 2014