Nov
24
2018

Intermittent Fasting May Benefit Health

There is a lot of discussion about the fact that intermittent fasting may benefit health. But there are a confusing variety of intermittent fasting schedules. This makes it difficult to compare notes regarding the specific effect of an intermittent fasting diet. Generally speaking when there is some form of calorie restriction, our body goes into a survival mode of operating. These types of diets provide enough nutrients to not get into malnutrition, but at the same time they may stimulate sirtuins, particularly SIR2. This is thought to be associated with longevity.

Various forms of fasting

Eating after 5 PM

The Taylors in the CNN article eat the same amount of calories, but they only eat after 5PM. They claim to have more energy and be less vulnerable to infections. They also think that they feel younger than in the past.

Fasting every other day

This was an observation in the 1980’s to help rats live longer compared to rats that have food available every day. Recent experiments on mice showed similar results: calorie restriction in whatever form leads to prolonged life and health.

Human fasting mimicking diet

A 2017 study on 100 humans divided this group into half. One half ate any food as they wished. The other half consumed only 800 to 1100 calories for 5 days of each month as a fasting mimicking diet. The experimental group had lower fasting blood sugars; cholesterol, triglycerides and other heart disease markers went down. The IGF-1 markers for various cancers also went down. The experimental group lost abdominal fat, but preserved lean body mass. Valter Longo, who co-authored the clinical study said that a human trial on longevity would almost be impossible to design, and would cost “a hundred million dollars or more. But if you look at the data from our trial … it would be hard to see how they would not live longer.”

5:2 diet

Patients are allowed to eat what they want for 5 days of the week, but then they restrict their diet for 2 consecutive days. The control group had no restriction of calories. The 5:2 experimental group had better glucose control and loss of abdominal fat than the control group.

Fasting can help you live-longer

Experts on calorie-restricted diets tell us that there is a switch in metabolism from burning glucose as fuel to using ketones as fuel. Extended periods of exercise will also cause a switch to using ketones as fuel. Repeated cycling from fasting to eating may also benefit our brain function. Intermittent fasting will help us cope better with stress and disease. But Dr. Longo says that this is only one aspect. He found in his research that with intermittent calorie restriction there is a multi-system regeneration going on. For instance, damaged white blood cells are depleted, stem cells are activated, blood sugar control is improved and heart risk factors are being controlled. Dr. Longo mentioned that when tissues are healthy and functional, risk factors for disease decrease.

Mechanisms behind longevity

Dr. Longo explained in detail the complex aging pathways that involve three components, IGF-1, mTOR and PKA. When lifestyle choices stimulate these genetic markers, accelerated aging is the consequence. But with the inhibition of those markers longevity will happen. Here are some of the effects on the body of a fasting mimicking diet.

  • Obesity diminishes, because of the weight loss effect due to missing calories.
  • Diabetes: insulin resistance becomes lower and blood sugar levels drop.
  • High blood pressure reduced: many patients were able to reduce their medications or discontinue them
  • Pain conditions improve as all kinds of pain disappears, an effect for which there is no explanation at this point
  • Autoimmune diseases like MS and rheumatoid arthritis improve, likely because of the effect of increased stem cell circulation
  • Prevention of heart attacks and strokes because of reduction of LDL, triglycerides and CRP
  • Cancer cure rates improve by protecting normal cells and the bone marrow
  • Longevity improved in mice with a 3-fold increase of their life span. Telomere length in humans was increased. Increased stem cells will find defective areas that need repair. This effect will open up a new chapter in medicine.
Intermittent Fasting May Benefit Health

Intermittent Fasting May Benefit Health

Conclusion

Calorie restriction is a powerful method to rejuvenate the body. Surprisingly 5 days out of one month of a calorie restricted fasting mimicking diet is all that is necessary to improve the body’s metabolism. Telomeres get increased, damaged white blood cells are removed and stem cells get stimulated. But weight loss, improvement of pain perception and cardiovascular risk reduction take place as well. In mice longevity was significantly prolonged, but this needs to still be shown in humans.

One can think of an intermittent fasting mimicking diet as a kind of internal cleansing. Following this it is easier to restart the metabolism with clean ingredients.

So far I have followed 11 courses of the fasting mimicking diet. But I don’t buy boxes of 300.00 USD every month. Instead I count calories myself, keep the diet balanced and buy the ingredients in the health food store. I agree that the fasting mimicking diet seems to be effective and it helps to keep my body mass index under control.

Nov
17
2018

Consumption Of Organic Food Reduces Cancer Risk

There are fewer carcinogens in organic food, which is likely why consumption of organic food reduces cancer risk. In an extensive study from France a large number of patients received questionnaires about their organic food intake.

The study was also reviewed by CNN using more popular language to describe the findings.

The French study showing that consumption of organic food reduces cancer risk

68,946 French adults were recruited for the study. More than ¾ of the study population were women in their mid 40’s. Researchers divided these subjects into 4 groups depending on how many of 16 organic food groups they were consuming.

First of all, the type of foods included fruit and vegetables, ready-to-eat meals, meat and fish, vegetable oils and condiments, dietary supplements and other products. Also, the investigators followed this population for an average of 4 ½ years. Finally, during that time 1,340 cancers developed. 459 breast cancers occurred, 180 prostate cancers, 135 skin cancers, 99 colorectal cancers and 47 non-Hodgkin lymphomas.

Most noteworthy, those who ate the most organic food developed 25% less cancer on average. When it came to Hodgkin’s lymphoma, organic food consumers developed 73% less of it than people on regular food. Postmenopausal breast cancer was 21% less frequent among those who had the highest use of organic food.

There are a number of factors regarding non-organic food that should make us pause to think.

Antibiotic use in agriculture

Milk and milk products are not as innocent as in the past when no marketing boards were around. Animals are no longer freely roaming on green pastures, but they exist in high-density facilities and they need antibiotics to prevent infectious illnesses. So the story goes. In reality farmers have found out that antibiotics and bovine growth hormone will both increase milk production. The manufacturers apply the profit principle and the result is that the consumers of milk and milk products have a change of their bowel flora from the antibiotic residues, which can cause heart attacks. The bovine growth hormone from milk and milk products causes breast cancer and prostate cancer. If you buy organic milk and milk products, you will not consume bovine growth hormone or antibiotic residues.

Immune disruptors

We know for several decades that insecticides used in agriculture on a large scale are accumulating in the body of the consumer and act as immune disruptors. The farmer feels he has to defend his crop against insects and sprays with various insecticides. Among the fruit with heavy spray residues are strawberries and apples.

Heavy metals

A study of the Consumer Reports’ from August 2018 examined baby foods. High levels of heavy metals like mercury, lead, arsenic and cadmium were detected in baby foods. Exposure to even low levels of heavy metals can lower a child’s IQ by 5 points.  Heavy metals have shown an association to behavior problems, to autism and to causing attention deficit hyperactivity disorder (ADHD). A study from New Zealand looked at how people who were exposed 4 decades earlier to heavy metals were doing when having an average age of 38 years.  565 New Zealanders showed measurements of high levels of heavy metals as children. Their IQ’s were lower than the average for their age and their socioeconomic status was below that of their parents.

Arsenic levels also high in organic food

It seems like heavy metals were high in both non-organic and organic baby food samples. Arsenic rice comes from inadvertent, but deliberate human poisoning. The Consumers Report explains that high arsenic values showed up in rice grown in these states: Arkansas, Louisiana, Missouri, and Texas. These are the same states, where cotton plantation covered the countryside in the past. The U.S. has been the world’s leading user of arsenic. Since 1910 farmers used about 1.6 million tons for agricultural purposes. Since the mid-1960’s they used only half of this amount. Although there was a ban of arsenic use as an insecticide in the 1980’s, residues from the decades of previous arsenic use still linger on in agricultural soil today. If organic rice is grown in these 4 contaminated states, it is not unexpected that even organic rice would contain high levels of arsenic.

Rice grown in previous cotton plantation areas contaminated by arsenic

The south-central region of the US was an area where cotton was the mainstay of agriculture for a long time. This is a crop where heavy treatment with arsenical pesticides was in use for decades in an attempt to combat the boll weevil beetle.

Rice was particularly high in arsenic, both in baby food as well as in adult food. Basmati rice from California, India, and Pakistan had on average half the amount of arsenic. Sushi rice from the U.S. was also low in arsenic.

Arsenic in chicken

A subsidiary of Pfizer produced the arsenic-containing drug, Roxarsone. This is an organic arsenic compound that accumulates in the liver of chickens. A synonym for Roxarsone is “3-nitro”. The full chemical name is 3-Nitro-4-hydroxyphenylarsonic acid.

When you read the fine print of the FDA website, it reveals that originally it allowed 3-Nitro® to be marketed in 1944 based on negative toxicity studies on rodents. The drug was approved again in 2009 for combination use with other drugs for suppression of coccidiosis, a cause of diarrhea in chickens. As 3-nitro is an organic arsenic compound. Researchers in the past believed that it would be non-toxic. So, the assumption was that it was safe to allow this feed supplement for chickens. It turns out that with more sensitive newer testing methods scientists from the FDA’s Center for Veterinary Medicine (CVM) and Center for Food Safety and Applied Nutrition (CFSAN) examiners found that organic arsenic compound metabolize in the chicken into cancer-causing inorganic arsenic compounds.

Chicken farmers use arsenic compounds to stimulate growth and to prevent the transmission of infectious diarrhea. If you don’t want to be a victim of the industry, I suggest you switch to organic chicken. It will be arsenic-free.

The “dirty dozen”

Originally the most polluted fruit and vegetables were termed the “dirty dozen”, but now the list is longer and includes 15 of the most polluted crop. They are: apples, peaches, nectarines, strawberries, grapes, celery, spinach, sweet bell peppers, cucumbers, cherry tomatoes, sugar snap peas (imported), potatoes, hot peppers, kale, and collards.

It is common knowledge for some time that certain foods contain more pesticide residues than others. Some of these fruit and vegetables contain between 13 and 15 different pesticides from spraying. Potatoes rank on top of all of the crops with high contamination.

Why is it important to know which crop has high pesticide contamination? Pesticides are immune disruptors. On the one hand vegetables are healthy for us, on the other hand they contain residues from insecticides and herbicides that have estrogen-like activities called xenoestrogens. They are are causing breast cancer in women and prostate cancer in men. If you replace all of these highly contaminated fruit and vegetables with organic ones, you will have reduced your cancer risk by 25%!

GMO foods and Roundup

It is interesting that there is no law in the US and in Canada that GMO foods should have a label declaring that it is genetically modified. This is changing rapidly as people realize that in many countries of Europe all GMO foods require labeling. Here is a publication that shows that the GMO labeling campaign is gaining momentum.

Genetically modified corn and soy contains the Bt toxin; it has been found in babies as mentioned in this article. Bt toxin damages the small bowel (the ileum) through Cry1Ab (the protein produced in genetically modified corn and soy). This in turn disables the absorption of vitamin B12. We know that this in turn will cause anemia. Historically the cause of pernicious anemia was due to a lack of vitamin B12 absorption.

Effects of Roundup

In a publication dated April 2013 Drs. Anthony Samsel and Stephanie Seneff discuss the effects of Roundup. They noticed that glyphosate inhibits the cytochrome P450 (CYP) enzymes in the liver. This is a crucial detoxification enzyme complex. When toxicity studies of glyphosate in mammals emerged, this was not common knowledge. The CYP enzymes in the liver are important to metabolize and eliminate estrogens and also help to detoxify xenobiotics, which are estrogen-like substances (residues from insecticides). Thus glyphosate (=”Roundup”) amplifies the damaging effect of environmental toxins and chemical residues from non-organic food that we eat. Researchers have shown a build-up of estrogens and xenoestrogens that are responsible for the development of many cancers (atypical Hodgkin’s lymphoma, breast cancer, prostate cancer, colon cancer etc.). Based on this data it makes sense to switch to as much organic food as you can afford. At least stay away from the “dirty dozen”!

Changing over to organic food, as consumption of organic food reduces cancer risk

If you want to avoid Roundup, xenoestrogens and GMO foods, you need to switch from regular foods to mostly organic foods. Throw out all the foods in your fridge that are not organic and that contain MSG in it’s many disguises. MSG is an excitotoxin, which kills brain cells. These suggestions are also what Dr. Paula Baillie-Hamilton is recommending.

Organic foods do not contain any of the problematic GM foods. They are free of rBGH, xenoestrogens, residual herbicides or residual insecticides. Switch to either organic milk and milk products or goat milk and goat milk products. Another choice would be “milk” products based on pea protein, but not on soy protein. As fatty tissue releases some toxins, it is advisable to use psyllium seed husks as a fibre source supplement to bind the toxins in the gut for elimination.

Consumption Of Organic Food Reduces Cancer Risk

Consumption Of Organic Food Reduces Cancer Risk

Conclusion

A French study involved 68,946 French adults; the researchers observed them for an average of 4 ½ years. They were divided into 4 groups depending on how many of 16 organic food groups they were consuming. During that time 1,340 cancers developed. 459 breast cancers occurred, 180 prostate cancers, 135 skin cancers, 99 colorectal cancers and 47 non-Hodgkin lymphomas. Consequently, the researchers found that those who were eating the most organic foods developed 25% less cancer on average.

When it came to Hodgkin’s lymphoma, organic food consumers developed 73% less of it than people on regular food. Postmenopausal breast cancer was 21% less frequent among the highest consuming organic food group.

Switching to organic food

I explained in detail how these cancer statistics come from traces of arsenic in chicken and rice, xenoestrogens from pesticide residues in non-organic vegetables, heavy metals, GMO produce and Roundup. It is time to take food seriously and switch to organic food. I have done this since 2001. Read labels carefully. Manufacturers often use the term “natural” to give a product a virtuous gloss-over. If you find that not all fruit or vegetables are readily available as organic produce, stay away from the “dirty dozen” and make use of the “clean fifteen”. You have a good variety to choose from: sweet corn, avocados, pineapples, cabbage, onions, frozen sweet peas, papayas (as long as they are not genetically modified), asparagus, mangoes, eggplant, honeydew, kiwi fruit, cantaloupe, cauliflower and grapefruit.

Oct
13
2018

Distribution Of Obesity In Women And Men Is Different

The distribution of obesity in women and men is different, when they gain weight on a low fat/high carb diet. The distribution of fat follows a pear shape in women due to fat accumulated around the hips. In males excessive fat accumulates around the waist, which gives them an apple shape appearance.

Researchers at the University of California, Riverside (UCR) have done experiments using a mouse model. They wanted to see what changes take place when obesity develops. Djurdjica Coss was the lead researcher of the study from the UCR School of Medicine.

The reason why this study was thought to be necessary

Many men and women have relatively normal weights until their mid 50’s. But when women approach menopause, they tend to accumulate fat in the thigh areas (pear-shape obesity). When their weight continues to rise, they also accumulate weight in the abdominal area. It is general knowledge that the fat in the abdominal region is metabolically more active producing inflammatory kinins.

Men above the age of 50 or 60 are also accumulating fat, but typically in the abdominal area right away. The name for this is apple-shape obesity. Unfortunately this is the fat we just discussed, metabolically active with inflammatory kinins. It is known to be the cause for heart attacks and strokes as it accelerates hardening of the arteries in the whole body. Dr. Coss found in doing experiments on mice that estrogen plays a major role in the development of obesity as discussed below.

The mouse experiments to study the development of obesity

The research team of Dr. Coss compared a group of mice that had their ovaries taken out. The ovaries in females are the main source of estrogens. They fed them a high-fat diet comparing their weight gain to that of male controls on the same diet. Obesity leads to a change in metabolism, called metabolic syndrome. This condition has an association with the production of inflammatory substances originating from the abdominal fat accumulation. Both male and female mice underwent a series of blood tests. They were also physically inspected. The female mice had the pear-type accumulation of fat, the males an apple-type fat accumulation.

More details about what obesity did to the experimental mice

In males there was a reduction of sperm count in the obese group as well as low muscle strength. In addition they were low in energy, had a lack of libido and their testosterone levels were low. The sperm number and the testosterone level had fallen to 50% of what they were when their weight was normal. This is what happens in human obese males as well. The inflammatory substances, that the abdominal fat creates, broke down the blood/brain barrier, and this affected the brain.

Among the female mice there was no neuroinflammation in the brain. There was no change in their hormones, which was quite a remarkable finding. This was a surprise and points out that beside estrogens there are other mechanisms to protect females from the effects of obesity.

Brain inflammation from obesity

Dr. Cross explained that in male mice the fat accumulation was of the apple-type. Female mice had the pear type fat accumulation. The fatty tissue in females did not release inflammatory kinins. On the other hand, the abdominal fat in the males released inflammatory kinins. These attracted macrophages, which is a cell type of the immune system. Activated macrophages now became aggressive and broke down the blood/brain barrier. This resulted in neuroinflammation of the brain. The brain normally is an immune protected site because of the blood/brain barrier. When this breaks down because of the action of inflammatory kinins from abdominal fat, the brain starts to develop memory loss like in Alzheimer’s disease.

Women before and after menopause

In females who still produce enough estrogen, fat from the pear type obesity distribution does not produce inflammatory kinins. This explains the relative protection of premenstrual women from heart attacks and neuroinflammation. But menopausal women start accumulating fat around the abdomen as well. At that point they can also develop inflammatory kinins and neuroinflammation. This is why the heart attack and stroke rate increases in postmenopausal women with apple-shape obesity.

Other studies supporting the effects of obesity in men and women 

Inflammatory substances in obese people affecting their brain

This publication shows that in a group of 141 neurologically healthy obese individuals the anti-inflammatory defense in the brain was weakened. Subsequently, various brain conditions developed because of the inflammatory substances affecting the brain.

How obesity affects your body functions

Obesity affects the body in various ways. It is particularly the apple type obesity that causes inflammatory substances circulating in the blood. A multitude of conditions can develop from this.

  • The cholesterol shows an increase of the bad LDL cholesterol and a reduction of the good HDL cholesterol.
  • The blood pressure rises. Without treatment high blood pressure can cause strokes.
  • Type-2 diabetes often develops because the insulin production cannot keep up with the demand. A second factor is a loss of insulin receptor sensitivity. As a result the insulin receptors of the body cells become resistant to insulin.
  • The gallbladder often develops stones, which may require gallbladder surgery.
  • Some cancers are increasing in frequency: endometrial cancer, breast, colon, kidney, gallbladder, and liver cancer.
  • Anxiety, depression and other mental disorders are more common, in part because of the neuro-inflammatory processes that I mentioned before.
  • Body pain and problems with physical functioning: obese people have more back pains, hip and knee pains from the extra weight. Slim people are less likely to have these problems. Obese people require more hip and knee replacement surgeries for end-stage arthritis than slim people.

Difference of metabolism in pear-shape versus apple-shape obesity

Back to the pear versus apple distribution of fatty tissue in obesity. diabetes, heart disease, high blood pressure and strokes as the apple type obesity. The difference in metabolism between the two is explained in detail here.

Distribution Of Obesity In Women And Men Is Different

Distribution Of Obesity In Women And Men Is Different

Conclusion

You may have heard that women tend to accumulate fat more around their hips, possibly because of hormonal factors. This is a pear-type fat distribution. In men who turn obese the fat accumulation follows an apple pattern. This type has a more aggressive metabolism in the fat tissue with inflammatory kinins accessing the blood circulation. It also affects the blood/brain barrier. Normally this barrier does not allow proteins to enter the brain. But when a person is obese, inflammatory kinins and proteins can enter the brain freely causing mental illnesses like depression and anxiety. Many obese people also develop type-2 diabetes leading to heart attacks and strokes.

Low fat diet from the 1980’s

The low fat diet of the 1980’s has caused a lot of obesity around the world. The problem is that merchants who provide low fat products have replaced fat with refined sugar. The liver converts refined sugar into fatty acids and triglycerides. These end up as fatty tissue. Given enough time this is causing obesity. Those who are obese need to cut out refined sugar in its many disguises. In addition they also need to cut down their starchy food intake. In the gut starchy foods break down into sugar.

When you cut out sugar and starchy foods, a person will typically lose 50 pounds in 3 months, at which point they have lost the label of “obesity”. They will also feel more energetic. The best advise for you is to maintain your weight loss with a Mediterranean diet. Research studies have shown that it is beneficial and anti-inflammatory.

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Sep
22
2018

The Best Foods For Your Heart

In the following I will describe 16 foods, which are the best foods for your heart. I will also comment as to why I believe they are best. This review is based on this article in “Medical News Today”.

But I have added many other comments to it.

Heart disease is still the number 1 killer. We need to change what we eat.

Vegetables

The regular intake of green leaf vegetables and cruciferous vegetables (broccoli, cauliflower and cabbage) has an association with the  preservation of cognitive function. In the Nurses’ Health Study starting in 1984 women were asked about their usual intake of a specified portion of food items, including 15 fruits and 28 vegetables. At a later date, between 1995 and 2001, researchers decided to ask the oldest participants (70 years and older) to participate in a cognitive function study. Two years later researchers repeated these tests.The main finding of the study is that women with the highest intake of green, leafy vegetables had the least decline in their cognitive function. The vegetable lovers, who consumed five serving of cruciferous vegetables, like broccoli, cabbage and cauliflower had less decline in their cognitive function. On the other hand the highest decline showed up in the group that averaged only 2 servings per week.

Asparagus

Asparagus is a source of fiber, folate, multiple vitamins and chromium. Chromium enhances the function of insulin to transport sugar into cells. Asparagus contains glutathione, a powerful antioxidant that neutralizes free radicals and carcinogens. It is said to help prevent lung cancers, larynx cancer, and bone, breast and colon cancers.

Berries

Berries like strawberries, raspberries, blackberries and blueberries are full of bioflavonoids. These are antioxidants, which prevent cardiovascular disease.

It is the anthocyanines, which prevent oxidation of LDL cholesterol. Berries also have bioflavonoids and reduce lipid formation in the blood. Berries contain fiber, folate, iron, calcium, vitamin A, and vitamin C.

Broccoli

This fiber rich vegetable helps to prevent hardening of the arteries. Broccoli and kale likely have preventative effects against colon cancer.

Chickpeas, beans, peas and lentils

Legumes or pulses are a great way to consume plant-derived protein. People who are on vegan diets should be eating them for a protein source. They also contain lots of fiber, vitamins and minerals. We know that they lower cholesterol, which prevents heart disease. Other healthy nutrients they contain are bioflavonoids, which have antioxidant properties and help prevent cardiovascular disease.

Dark chocolate

This is a food rich in antioxidants. Dark chocolate is chocolate with more than 70% cocoa content. Please note: “milk chocolate” is nothing better than candy and devoid of any health benefits. Dark chocolate increases the protective HDL cholesterol and prevents oxidation of LDL cholesterol. It is said to prevent atherosclerosis (hardening of the arteries). Don’t exceed eating 1 to 2 oz. per day, as chocolate has some sugar in it and the fat content would be detrimental with higher consumption.

Chia seeds and flaxseeds

Chia seeds and flaxseeds are rich in omega-3 fatty acids in the form of α-linolenic acid (ALA). ALA reduces LDL cholesterol and it dissolves plaque in the arteries. ALA also reduces blood pressure to a certain degree. All of this helps reduce cardiovascular disease (heart attacks and strokes). Note that flaxseeds must be ground to powder to release the nutrients from its tough shell. Both chia and flaxseeds can be used as an egg replacement in vegan cooking.

Fish high in omega-3s

Omega-3 fatty acids are abundantly present in fish. It has plaque-reducing properties and also reduces the risk for abnormal heart beats. Overall this means less cardiovascular disease. The American Heart Association recommends a 3.5 oz. serving of fatty fish (salmon, mackerel, lake trout, herring or sardines) twice per week.

Coffee

A Brazilian study from 2018 showed that drinking 3 cups of coffee a day would stop coronary artery calcification. Many other studies have shown reduced mortality from heart attacks and strokes with increased coffee intake.

Green tea

Green tea is known to reduce blood pressure slightly and to reduce cholesterol. Both effects are beneficial for the cardiovascular system (prevents heart attacks and strokes). Green tea also prevents many cancers. Whatever we know about coffee consumption seems to also be true for green tea consumption.

Nuts

Nuts contain healthy fatty acids (omega-3). But they also contain fiber, protein, minerals, vitamins and antioxidants. Use them in desserts, in salads and as a quick food on the go. They are definitely healthier than protein bars.

Liver

Liver is one of the nutrient rich foods. It is rich in iron, phosphorus, vitamin A, folate, vitamin B12 and biotin.

Oatmeal

Oatmeal is rich in soluble fiber. It has been shown to lower LDL cholesterol and total cholesterol. This is important for prevention of heart disease.

Red wine (may be)

The bioflavonoids of red grapes have been the subject of much research. There is a dose-response curve showing a protective effect with regard to heart attacks and strokes with the consumption of  1 to 3 glasses of red wine per day. But unfortunately there is also a dose-response curve with respect to alcohol consumption and cancer causation. Personally, I take resveratrol from the health food store, 500 mg daily and consume white wine or red wine very rarely.

Tomatoes

There are a number of beneficial phytochemicals in tomatoes. Carotenoids like lycopene, lutein, zeaxanthine and beta-carotenes are helping to prevent prostate cancer and colon cancer. Potassium and folate are cardioprotective.

Spinach

Eating spinach regularly will provide you with magnesium, iron and bioflavonoids. Magnesium is good for a regular heart rhythm. The other nutrients are good for skin, bone and hair health.

Discussion

I have reviewed why these 16 foods are the best foods for your heart. We have seen that many foods that are rich in antioxidants are also cancer preventative. People who eat a Mediterranean diet will get these 16 foods, because their meals are balanced with nutrients. But if you eat a hamburger or a pizza you will not get balanced nutrients. The more one-sided your food intake, the more dangerous your lifestyle becomes. This is the problem with the Standard American diet (“SAD”). You need all of the components of the 16 foods described here. Junk food won’t do, as it consists only of empty calories.

The Best Foods For Your Heart

The Best Foods For Your Heart

Conclusion

It is useful to review healthy foods as was done above. Now it is a matter of including them in your daily food intake. If this is overwhelming you, start with baby steps. One or two healthy foods here or there are a good start. Increase this until you cover all the 16 foods mentioned. The more balanced your food intake is, the more antioxidant vitamins you will get. And the more heart disease and cancer prevention you will experience.

Apart from good, balanced nutrition we also need regular exercise for heart disease and cancer prevention. Go to a gym, go for a walk, climb some stairs. Get away from the computer and television. Together with best foods for your heart this will keep you healthier for longer.

Sep
15
2018

Moderate Carb Intake Has The Lowest Mortality

A 25-year long study has shown that a moderate carb intake has the lowest mortality. A comprehensive study from the US has followed more than 15,000 men and women for 25 years. They were between 45-64 years when they entered the study and they were from diverse socioeconomic backgrounds. The authors chose mortality as an end point. Dr. Sara Seidelmann is a clinical and research fellow in cardiovascular medicine from Brigham and Women’s Hospital in Boston. She was the lead author of this study. The research group used food questionnaires and analyzed the carb content in the food. They also determined what percentage of the food composition was of animal origin or plant origin.

Research study finds moderate carb intake has the lowest mortality

The main findings of the study were that less than 40% of carbs in the diet led to an increased death rate with a mortality of between 1.4-fold and 1.8-fold. On the other hand, more than 70% of carbs in the diet also had increased mortality rates of 1.2-fold. The lowest mortality was in the group that consumed a diet where carbs were between 50% and 55%. Dr. Seidelmann explained that in terms of life expectancy the result of the study could be summarized as follows. A 50-year-old person had another 33 years to live when carb intake was in the moderate range. The low-carb person had only another 29 years to live (4 years less than the moderate carb person). The high-carb person lived another 32 years, 1 year less than the moderate carb person.

Plant-derived versus animal-derived fat and protein

The study showed that there was increased longevity when carbohydrates were exchanged for proteins and fats from plant sources. Mortality was 18% less for this group. Conversely, when carbs were replaced for animal-derived fat or protein mortality was 18% more!

Dr. Seidelmann noted that this study was coming from a US based population. In the case of an Asian group they would consume much more carbs on average, but they would replace a lot of the animal fat and protein with fish. Fish is a healthier source of protein and fat than beef or pork.

A moderate carb intake group that used protein and fat from animal sources was compared to plant sources. When protein and fat had the origin from lamb, beef, pork, and chicken the mortality over 25 years was higher. When protein and fat came from vegetables, such as nuts, peanut butter, seeds and whole-grain breads there was a lower mortality rate.

Other studies comparing the effect of animal protein versus plant protein

  1. A 2016 study that had gone on for 49 years was involving 131,342 participants. Animal protein intake showed an association with higher mortality from heart attacks and strokes. 3% of energy from processed red meat was now substituted by an equivalent amount of plant protein. This reduced the all-cause mortality by 34%, for unprocessed red meat by 12% and for egg by 19%.

 

  1. Red meat is cancer-producing. Several studies have shown this. When red meat is digested, cancer-causing substances are released that can be the cause of cancer in the lining of the stomach and the colon. The above link says we should limit red meat consumption to 65 grams (2oz.) per day or 2 servings (130 grams or 4 oz.) 3 to 4 times per week. We should avoid eating more than 455 grams (1 pound) of lean red meat per week.

Triglycerides are an independent risk factor for heart attacks

In this publication evidence is also present that triglycerides are an independent risk factor that can cause heart attacks.

When you eat too many carbs, the body produces the excess you don’t need into triglycerides, and it deposits its subsequently as fat in fatty tissue.  Physical activity burns up some of the triglycerides. But when we eat too much refined sugar and starchy foods, there will be an excess of triglycerides putting our blood vessels and our hearts at risk.

Regular exercise prevents disease and premature deaths

Many studies have shown that regular exercise prevents heart attacks and premature deaths. We even know the mechanism of why this is so. Exercise releases nitric oxide ((NO) from our blood vessels, which widens the arteries. This also prevents high blood pressure. Exercise elevates the protective HDL cholesterol. When regular exercisers were compared to a non-active group they had a 41% lower risk of death. All-cause hospitalizations were down by 21% and cardiac hospitalizations were down 32%.

Discussion

  1. Barry Sears is the inventor of the Zone Diet. I attended a lecture in 2001 at an Anti-Aging Conference in San Diego. Dr. Sears was the keynote speaker at this conference. He stressed that a diet with 55% of complex carbs would be the best diet. It is interesting that Dr. Seidelmann in the study mentioned in beginning of this blog found the same thing. The lowest mortality was in the group that consumed a diet where carbs were between 50% and 55%.
  2. The second point that is important to note is that it matters whether we eat protein derived from animals or from plants. Even small steps help. When we reduce our animal protein intake by only 3% of the energy intake, and replace it by plant protein, there is a significant reduction in mortality.
  3. Exercise is rarely mentioned in relation to diets. But exercise needs to be included every day and you will experience a reduction of cardiac hospitalizations of 32% as mentioned above.
Moderate Carb Intake Has The Lowest Mortality

Moderate Carb Intake Has The Lowest Mortality

Conclusion

A moderate carb intake, as is the case in the Mediterranean diet and in the Zone Diet of Barry Sears, has the lowest mortality rate. Complex carbs (in vegetables) are absorbed much slower. As a result the risk for heart attacks is much lower. The opposite is true for refined carbs from sugar. They cause heart attacks and strokes with premature mortality. Dr. Sara Seidelmann led a study at the Brigham and Women’s Hospital in Boston that lasted 25 years. Less than 40% of carbs in the diet led to an increased death rate with a mortality of between 1.4-fold and 1.8-fold. These diets are paleo-type diets, the Atkins diet and the ketogenic diet. More than 70% of carbs in the diet also had increased mortality rates of 1.2-fold.

The healthiest diet

People who consumed a diet where carbs were between 50% and 55% had the lowest mortality rate (Zone Diet). Another finding of this study, which was confirmed by others is that animal-based protein is unhealthier than plant-based protein. Even replacing 3% of energy from an animal-based diet with plant-derived protein delayed mortality significantly.

If you want to live longer and stay healthy you need to critically evaluate what you eat.

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Aug
25
2018

The Downside Of Living To 100

A review article has examined longevity and reviewed the downside of living to 100. In their 80’s about 10% of the population live in nursing homes, but among centenarians 55% are residing in nursing homes. They are often very lonely, as their social circles have shrunk as they aged.

Common diseases of older people

Osteoarthritis makes it difficult for people to get around, it causes chronic pain and it can also be the reason for falls. In 1990 there were 213.4 cases of osteoarthritis per 100,000. 26 years later, in 2016 there were 232.1 cases of osteoarthritis per 100,000 people.

Chronic obstructive pulmonary disease (COPD) has been falling, because less people smoke cigarettes now. Statistics show 1667 cases of COPD per 100,000 in 1990, but only 945 cases of COPD per 100,000 in 2016.

Diarrhea and common infections have dropped sharply from 8951 per 100,000 in 1990 to 3276 per 100,000 in 2016.

What other common diseases do older people get?

There are a number of common diseases that affect the elderly.

Osteoarthritis

Osteoarthritis of the hips and the knees are common, but it can affect every joint in the body. In the end stage knee replacements or hip replacements may be necessary. But before a total knee replacement or total hip replacement can even come into consideration, the person’s heart needs a thorough checkup to ensure that it is safe for the patient to undergo surgery under a general anesthetic.

Heart disease

Older people often have heart disease.

When coronary arteries are narrowed, heart attacks occur. Cardiologists can place stents, so that previously narrowed coronary arteries receive normal blood flow. Following such a procedure the patient may live for another 10 to 15 years.

There are also heart valve calcifications. The aortic valve is particularly endangered. A heart surgeon may be able to replace a diseased aortic valve by a porcine valve.

The nervous system of the heart transmits electrical signals from the sinus node to the muscle fibers, which can get diseased. Heart rhythm problems may necessitate the insertion of a pacemaker.

Finally, the heart may enlarge, but pump less blood than before. This condition is congestive heart failure. The 5-year survival for this condition is only 50.4%. Unfortunately there is very little the doctor can do for patients like this.

Cancer

The older we get, the more DNA mutations we accumulate. At one point cancer develops. If the diagnosis happens at an early stage there is a good chance that surgery can remove a cancerous growth, and the patient survives. But there are cancers that are notoriously difficult to recognize in the early stages. These are: cancer of the pancreas, kidney cancer, stomach cancer and certain types of leukemias.

Respiratory diseases

Those who smoked earlier in life may develop chronic obstructive pulmonary disease (COPD). It is a chronically disabling lung disorder. Often these individuals have to carry an oxygen tank with them wherever they go. The 5-year survival rate for people with COPD is 40 to 70%.

Osteoporosis

Osteoporosis is a disease where the bone is brittle. Spontaneous bone fractures can occur at the wrists, the upper thigh bone (femoral fractures) or in the vertebral bones. Women in menopause are hormone deficient and this contributes to calcium depletion of the bones. Lately research has shown that vitamin K2 and vitamin D3 are necessary for a normal calcium metabolism. Briefly, 200 micrograms of vitamin K2 and 5000 IU of vitamin D3 every day are the necessary dosage that the body can absorb calcium from the gut, eliminate it from the blood vessels and deposit it into the bone. Calcium is present in milk products and milk. If a person does not consume enough milk products a supplement of 1000 mg of calcium daily does make sense.

Alzheimer’s

The older we get, the more likely it is an onset of Alzheimer’s or dementia. Between the ages of 90 to 94 there is a yearly increase of Alzheimer’s of 12.7% per year. The group from age 95 to 99 years has a yearly increase of Alzheimer’s of 21.2% per year. Persons aged 100 years and older have an increase of Alzheimer’s by 40.7% per year. What this means is that essentially there is a doubling of Alzheimer’s every 5.5 years. We do not have all of the answers why this is happening and why Alzheimer’s develops. But we do know that diabetics are more likely to develop Alzheimer’s. High blood sugar levels and high insulin levels seem to lead to the precipitation of the tau protein in the brain, which causes Alzheimer’s.

Diabetes

When diabetes is not well controlled, there is accelerated hardening of the arteries. This can cause heart attacks and strokes. Longstanding diabetes can affect the kidneys (diabetic nephropathy, kidney damage) and can lead to hardening of the leg arteries. Often the only treatment left is a below knee amputation. Blindness from uncontrolled diabetes is common and pain from diabetic neuropathy as well.

Diabetics have an average life expectancy of 77 to 81 years. However, if they pay attention to their blood sugars and manage their diabetes closely they can live past the age of 85.

Falls and balance problems

As people age, their balance organ is not functioning as well. Also, people with high blood pressure medication may have postural hypotensive episodes that can lead to falls.

There may be a lack of cognitive functioning and misjudging of steps, ledges and irregularities in the floor. When a person has brittle bones from osteoporosis and they fall, a hip fracture is very common. At a higher age surgery for a hip fracture is dangerous. It can have a mortality of 50%.

Obesity

A person with obesity has a life expectancy that is 10 years less than a person without obesity. The reason for this is that with obesity This is so, because the risk of heart attacks, strokes, cancer, arthritis and diabetes is increased.

Depression

Older people often get depressed. It even has its own name: involutional depression. People can get into a state of mind, where they think negatively. Depressed people feel that they have nothing to live for. They lost friends; they are shut in because they can’t drive a car any more. This type of depression needs treatment by a psychologist or psychiatrist. The danger of leaving depression untreated is that the person may get suicidal. In older people depression is often precipitated by physical health problems.

Oral health

When teeth are not looked after, gingivitis and periodontitis can develop. Infected gums can shed bacteria into the blood and this can affect the heart valves. Endocarditis, the infection of heart valves, is a cardiological emergency. Prolonged antibiotic therapy is necessary to overcome this condition.

Poverty

Poverty has real consequences. The aging person may not have access to the optimal medical care facility because of a lack of funds. But even at a younger age there is evidence that people are healthier when they are wealthier.

Shingles

Older people often get shingles, even if they had chickenpox or shingles as a child. This is evidence that the immune system is getting weaker. Shingles in an older person should alarm the treating physician that there could be an underlying cancer. Due to that knowledge a cancer-screening tests should be part of the medical exam. In addition, a varicella vaccine should be offered to the patient to build up immunity.

The Downside Of Living To 100

The Downside Of Living To 100

Conclusion

Living to 100 is often glorified in the press. Maybe you have seen a 90-year old jogger completing a marathon, or you saw an 85-year old couple ballroom dancing. But what they don’t show you is what I summarized here, the less glamorous things about living to 100. You may get a heart attack or a stroke. Osteoarthritis may affect you how you walk. Congestive heart failure may make you get short of breath when you walk upstairs. Then there are various cancer types that are difficult to diagnose early.

If you have smoked in the past, you may suffer from chronic obstructive pulmonary disease (COPD), which leaves you breathless.

Other illnesses

Osteoporosis can lead to spontaneous fractures. Because the bone has a lack of calcium, this is difficult to treat and takes a long time to heal.

Alzheimer’s is ever so much more common when you approach the year 100. There are other medical conditions you can get: obesity, diabetes and depression. When you get shingles for the second time, it may mean that your immune system is getting weak and a cancer-screening test should be done.

There are some downsides when you approach the age of 100.

Know your risks and be vigilant

You may keep your physician busy checking out various age-related illnesses, but more importantly, get regular check-ups and tests. Any condition is easier to treat with an earlier diagnosis! The message for anybody reading this is very simple. Prevention through healthy living is something you can actively pursue. Keep your body and your mind busy. Enjoy time with friends and family instead of living a solitary existence. See the glass that is half full instead of viewing it as half empty. Stick to a healthy diet. Knowing all the risks is not a scare but a call to being vigilant. Knowledge is powerful and will help you to enjoy your golden years feeling well and happy.

Aug
18
2018

Poor Diet Habits Can Cause Alzheimer’s

A new study from the Brock University in St. Catharine’s, Ont. showed that poor diet habits can cause Alzheimer’s. Specifically the risk for Alzheimer’s was a combination of high saturated fats in the diet in combination with too much sugar.

The third triggering factor was the normal aging process that also contributed to the development of Alzheimer’s.

The study showing that poor diet habits can cause Alzheimer’s

Master student Bradley Baranowski and PhD student Kirsten Bott conducted the experiments under the supervision of Assistant Professor of Health Sciences Rebecca MacPherson. The experimental group consisted of middle-aged mice that were observed for 13 weeks. They received a high-fat/high-sugar diet. The control group received a normal diet.

The experimental group with the high fat/high sugar diet was aging prematurely. They also showed elevated inflammatory markers, elevated insulin levels and cellular stress. Dr. Rebecca mentioned that the middle-aged mice would be comparable to humans aged 40 to 60. “[We’re] trying to see what the initiating signals are that can lead to progression of Alzheimer’s disease,” MacPherson said.

Lifestyle choices matter

“People often view Alzheimer’s disease as a genetic disease when in fact, genetic mutations leading to Alzheimer’s accounts for less than five per cent of cases,” Baranowski said in the press release. “This study highlights that our lifestyle choices matter and can potentially put us at risk of developing or progressing neurodegenerative diseases such as Alzheimer’s.”

Other studies that support the concept that lifestyles matter

Over the years many other researchers have analyzed what factors contribute to getting Alzheimer’s. It probably is a combination of several factors.

Age

Age is one of the major risk factors. Most Alzheimer’s patients are above the age of 65. Above 65 the risk doubles every 5 years. By the time we are 85 our risk is 1/3 to get it.

Family history

If you have a parent, brother or sister who came down with Alzheimer’s, you have a higher risk of getting it.

Environmental factors

Often environmental factors like eating too much sugar or too much saturated fat are confused with family history factors. Nutritional habits in a family can be like a tradition. It may appear as if this is a family history of Alzheimer’s when in reality poor eating habits were passed on from generation to generation. A lot more research is necessary in this area.

History of Head injury

A history of a closed head injury carries with it a higher risk of Alzheimer’s later in life. We need to use seat belts in cars and helmets when bicycling. Avoid risky sports activities where you would sustain a traumatic brain injury.

Heart disease

There is a link between heart disease, diabetes, stroke, high blood pressure, high cholesterol and Alzheimer’s. When brain arteries get clogged, the brain deposits more beta-amyloid protein as plaques. This is a sign of early Alzheimer’s disease.

Older Latinos and older African Americans

Older Latinos have a 1 ½-times higher risk than older whites to get Alzheimer’s and dementia. On the other hand older African-Americans are 2-times more likely than older whites to come down with Alzheimer’s. The reason for this is not entirely clear. But a big factor likely is the cardiovascular risk that is higher in Latinos and African Americans. This translates into a higher risk for Alzheimer’s.

Prevention of Alzheimer’s disease

There are more publications that point out that Alzheimer’s disease is largely preventable by cutting out those factors that contribute to its development.

Here is a list of steps to follow in order to prevent Alzheimer’s disease.

  1. First of all treat diabetes, high blood pressure and obesity aggressively. This eliminates cardiovascular risk factors, which keeps the brain vessels open.
  2. Furthermore quit smoking. By preserving the cardiovascular system the brain stabilizes.
  3. Another important factor is physical activity: exercise daily! This maintains cardiopulmonary fitness. It also keeps your brain vessels open.
  4. Also, take care of your diet: eat balanced meals and avoid junk food. A Mediterranean diet or the MIND diet are examples of diets that help prevent Alzheimer’s. Note that these are low sugar and low saturated fat diets. This fits the initial observation that you read in the beginning of this blog. Mice on a high fat/high sugar diet showed premature aging and developed Alzheimer’s. Knowing this, it is good to do the opposite: cut out excessive saturated fats and sugar. Sugar increase LDL cholesterol and triglycerides, which leads to hardening of arteries.
  5. Mental stimulation is another important factor for preventing Alzheimer’s. With lifelong bilingualism there was a delay of about 4.5 years in onset of dementia. The ACTIVE study is in the link above. It showed that mental stimulation could indeed delay the onset of Alzheimer’s over a 10-year period. 
Poor Diet Habits Can Cause Alzheimer’s

Poor Diet Habits Can Cause Alzheimer’s

Conclusion

Above all, I cannot emphasize enough how important a healthy diet is for a healthy mind. The combination of an overabundance of saturated fats and refined sugar was found to be the cause of premature aging in mice. But likewise, we know from human trials that this also causes premature aging in humans and higher incidence of Alzheimer’s. As a result, it is logical to recommend a lower intake of saturated fat and to reduce sugar intake. It will prevent hardening of the arteries and slow down the development of Alzheimer’s.

But there are many other recommendations to avoid getting Alzheimer’s: quit smoking. Stay physically active by exercising daily. Use a Mediterranean diet or the MIND diet to prevent Alzheimer’s. Clinical trials with these diets have shown them to be effective. Treat diabetes, high blood pressure and obesity aggressively as this will stabilize your metabolism. As a result it also prevents Alzheimer’s. Finally, stimulate your brain every day by doing various activities. This forms new synaptic connections inside your brain and postpones Alzheimer’s from setting in as you age.

Jun
09
2018

What Makes Chips Addictive?

When you emptied an entire bag of potato chips, you may ask yourself: what makes chips addictive? Scientists talk about hedonic hyperphagia or hedonic hunger. In plain English, it is the pleasure of eating, even when you are not hungry. There are certain foods that seduce you to overeat, and one of these are chips. Chocolate or candy can be other high-hedonic rating foods.

Erlangen experiments

A group of researchers from the Erlangen University in Germany set out to get to the bottom of this addiction eating. 17 healthy subjects with a body mass index of between 19 and 27 were recruited for eating experiments. They got either high calorie chips or low calorie zucchini. The chips created a marked stimulation on a functional MRI scan where the nucleus accumbens was lighting up. When they consumed zucchini no such stimulation could be documented. The researchers had done similar experiments with the same foods on rats. They too had functional MRI scans and the tests showed similar stimulation after the test animals consumed chips, but not after zucchini.

Nucleus accumbens, the addiction center for food

Professor Andreas Hess and his team in Erlangen say that the nucleus accumbens is the addiction center for food. They also did experiments with fat to carbohydrate composition to find the most addictive mixture. There is a certain fat to carbohydrate ratio that triggers food addiction. What surprised the Erlangen researchers was that both in rats and humans the optimal addiction potential was identical.

  • They found that rats preferred 35% of fat and 45% of carbohydrates in their chips. With humans there is the other factor: on top of the fat/carb mixture we like to taste some salt and spices, because this also will stimulate our appetite. The food industry has figured this out long time ago. This knowledge from tasting experiments is built into processed food.
  • The Erlangen researchers  also found that in obese people the nucleus accumbens was lighting up more intensely the higher the BMI was. That means that obese people are more food-addicted!

Triggering the nucleus accumbens

  • Professor Hess postulates that the 35% fat to 45% carb mix in potato chips is ideal for the body. It can mobilize quick energy from carbs, but also have storable energy from fat at the same time. It is this mix, which stimulates the addiction center in the nucleus accumbens.
  • In a study from Bethesda, Maryland researchers found an overlap between food addiction and drug addiction.  The common pathways in both is the release of dopamine in the nucleus accumbens. This dopamine release makes us feel good, and as a result, we want to experience it again.
  • In this study patients with bulimia nervosa were examined. They found that   overconsumption of sugar-laden foods had very similar effects as drugs in drug-addicted patients. It is the release of dopamine, glutamate and the opioid system that are involved in both. The nucleus accumbens is also receiving stimulation in both situations.

What can be done about food addiction?

This publication noted that people who are food addicted eat higher amounts of fat and carbohydrates. With this mix the feel-good nucleus accumbens produces most dopamine, which is the driving force behind the addiction.

  • If you cut out sugar, you find it easier to control your eating portions. But you also must cut out processed food, as this is where a lot of hidden sugar is coming from.
  • Cut down on your fat consumption. Even if you reduce it from 35% to 10% or 15%, this is a huge step forward. It reduces your calorie intake significantly, but also reduces the stimulation of your appetite center.
  • Eat lots of vegetables, salads and some fruit. Be careful with some fruit like grapes, bananas, mangos, papayas and dates. They are all higher in sugars. If you cannot entirely avoid those, use portion control, so you are not overeating on them.

Portion control

Besides changing the food quality, you can reduce the portions of food you are eating. Instead of mindlessly emptying a whole bag of chips, you could get a small bowl and fill part of the bag of chips into it. Remove the bag into a cupboard that is difficult to reach. If you are sitting and watching TV, you could eat one chip at a time, but only during commercial breaks. This way your chip eating becomes more conscious and more controlled, and you set a limit. In time you may find that you can replace the chips with a lower calorie food like slices of apples, celery sticks or carrot sticks.

What Makes Chips Addictive?

What Makes Chips Addictive?

Conclusion

Researchers found that chips were addictive in rats and in humans. Functional MRI scans of brains in rats and humans showed that potato chip eating stimulated the nucleus accumbens. It was lighting up in both species when the test subjects consumed potato chips. Surprisingly, it did not matter, whether these were test animals or humans! A review of several research papers showed a similarity between food addiction and drug addiction. It is dopamine and other brain transmitters that stimulate the nucleus accumbens, which is the addiction center. One of the keys, professor Hess from Erlangen University in Germany found, is the fat/carb mix. When the potato chips contained 35% fat and 45% carbs, this stimulated the nucleus accumbens.

Changing your eating habits

Knowing all of this helps us to be able to change our eating habits. To avoid the pitfalls of food addiction, cut out sugar and starchy foods, and remove processed foods from your diet. Also reduce some of the fat to 10% or 15% fat in your total diet. Eat lots of vegetables and fruit low in sugar. In addition you should also consider with portion control to avoid mindless munching. Before you know it you can shed the pounds that you may have accumulated before. You will be able to reduce your BMI to 21 to 23. Many people have done it before you.

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Apr
28
2018

Animal Protein Is Bad And Nut Protein Good For You

Recently a study from California and France showed that animal protein is bad and nut protein good for you. This review goes back to  this original study from April 2, 2018.  Other studies have shown that there is a higher mortality with a meat-based diet.

How the study was done

Researchers followed 81,337 men and women from the Adventist Health Study-2 for a time of over 9.4 years. Between 2002 and 2007 they also researched the diet of the study participants. They used food frequency questionnaires. 2276 cardiovascular deaths occurred during the observation period. The risk for cardiovascular mortality regarding meat protein consumption was 1.61-fold. The cardiovascular risk for the nuts and seeds protein consumption group was 0.60. This means that the meat-consumers had a 61% higher heart attack and stroke rate. In comparison, the group that consumed nuts and seeds had 40% less heart attacks and strokes than people on a regular diet.

Discussion of the study

This study is rather large and went on for a long time (9.4 years). This gives the study great statistical power. The message from the study is quite clear. The more animal protein you eat, the higher your risk will be to succumb to cardiovascular disease. Having a heart attack or stroke prematurely will shorten your lifespan. In contrast, those whose protein source comes mainly from nuts and seeds are better off. They have a 40% lower probability to die from heart attacks or strokes.

Other studies regarding “animal protein is bad and nut protein good for you”

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Diabetes caused by red meats, processed meats, whole grains and sugar-sweetened beverages

A European study was analyzing risk foods that can lead to diabetes. https://www.ncbi.nlm.nih.gov/pubmed/28397016 The publication of the study was  in May 2017. Red meats, processed meats, whole grains and sugar-sweetened beverages caused a 3-fold higher risk to develop type 2 diabetes. This was compared to people avoiding those foods. Study participants consuming legumes and nuts had a low risk of developing diabetes. In between was a moderate risk group who ate refined grains, eggs, fruit, vegetables, dairy and fish. Consumption of risk-decreasing foods resulted in a 42% reduction of diabetes.

Foods that caused heart attacks and strokes

A March 7, 2017 study from Boston analyzed the key foods that cause increased mortality.  Intake of high sodium, highly processed meats, sugar-sweetened beverages and also unprocessed meats caused heart attacks and strokes. In addition, a lack of nuts/seeds, low consumption of seafood omega-3 fats, low vegetable and low fruit consumption also caused mortality from heart attacks and strokes.

Nuts reducing inflammatory biomarkers

A September 2016 study from Brigham and Women’s Hospital, Boston, MA looked at the correlation of nut consumption and an anti-inflammatory response. 5013 patients from the Nurses’ Health Study (NHS) and Health Professionals Follow-Up Study received food consumption questionnaires.

Research used two parameters for measuring inflammatory biomarkers: on the one hand blood tests checked the C-reactive protein (CRP), on the other hand they observed interleukin 6. Interestingly there was a correlation between nut consumption and decrease of inflammatory markers. When 5 or more helpings of nuts per week were part of the dietary habits, there was a 20% reduction in the CRP value and a 14% reduction of interleukin 6 , which was a difference to those persons who never consumed nuts. This is significant, because we know that inflammation of the lining of the arteries is a cause for high blood pressure, heart attacks and strokes. Inflammation of the arteries can also cause type 2 diabetes.

Dietary intake among US adults, 1999-2012

This June 2016 study has the title ”Dietary Intake Among US Adults, 1999-2012”. Comparisons were made between a previous dietary study of 1999-2000 and now. The investigators noted some improvements in dietary habits. The persons consumed more whole grains and nuts or seeds. They also had slightly increased fish and shellfish intake. On the other hand, consumption of sugar-sweetened beverages had decreased. But other food components like salt intake, total fruits and vegetables, processed meats and saturated fat had not changed. There was an increased consumption of whole fruit and a decrease of 100% fruit juice (which is sugar laden). Unfortunately there was also some bad news: low-income Americans still have poor food intake, so do non-Hispanic blacks or Mexican American adults.

Mediterranean diet can prevent cognitive decline

A July 2016 review shows that a Mediterranean diet can prevent cognitive decline like dementia and Alzheimer’s disease. In this overview the authors have collected evidence showing that adherence to a Mediterranean diet does indeed prevent cognitive decline. The Mediterranean diet consisted of intake of fruit, fish, vegetables and less consumption of sugar, red meat and dairy. The researchers found that the incidence of cancer, strokes, heart attacks and diabetes were all lower, as was dementia. They pointed out that MRI studies have revealed that the brain volume showed a reduction by 5% per decade after the age of 40. From the third to the 8th decade of our lives the short-term memory can show a reduction of about 50%.

Deterioration of general health related to cognitive decline

The authors point out that the combination of heart disease, stroke and diabetes are often an indication that the person’s overall health is declining. Cognitive decline will soon follow, when physical decline is evident. What people often do not realize is that all of these conditions are related to decades of poor diets. Change the diet to a Mediterranean diet, and your heart health will improve; also a stroke and diabetes may be prevented. The interesting observation is that often cognitive functioning also improves. This makes sense: if the brain circulation improves, oxygen and nutrients can reach the brain cells again and brain function can now improve.

Animal Protein Is Bad And Nut Protein Good For You

Animal Protein Is Bad And Nut Protein Good For You

Conclusion

I mentioned a recent publication, which stated that animal protein is bad and nut protein good for you. When I looked at other publications I found this confirmed. Finally I reviewed a study that investigated the use of the Mediterranean diet to improve cognitive function. It became apparent that physical illnesses, like heart attacks, strokes and diabetes, have also a connection to a loss of cognitive function in older age. It may point to a general aging of the lining of the arteries. An anti-inflammatory diet, like the Mediterranean diet, has the potential to improve the lining of the arteries. This leads to a reduction of medical problems like heart disease and diabetes. In addition it can also reverse cognitive decline. The switch to a Mediterranean diet is not dramatic! It can, however, dramatically improve your overall health and wellbeing as you age.

More info: https://www.askdrray.com/healthy-olive-oil/

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Apr
14
2018

Where Does Fat Go With Weight loss?

People often wonder where does fat go with weight loss? This question recently came up in a CNN conversation.  The answer was originally researched by Dr. Ruben Meerman and Professor Andrew Brown.

Dr. Meerman is an assistant scientist at the University of New South Wales and author of “Big Fat Myths: When You Lose Weight, Where Does the Fat Go?” Professor Brown is the head of the School of Biotechnology and Biomolecular Sciences at the same university.

When you lose 1 kilogram of fat, where does fat go with weight loss?

The interesting answer to this question is that fat gets metabolized. Dr, Meerman and Prof. Brown pointed out that originally Leifson et al. answered this question who used heavy oxygen and found out that this was metabolized into heavy water.

Technically these experiments are fairly complex, but they allow the researchers to see exactly where the body incorporates these chemicals and where they end up with breakdown of fat. The BMJ paper describes that the breakdown of 1 kg of fat follows the following pattern: It breaks down into 0.84 kg of CO2 (carbon dioxide) and 0.16 kg of H2O (water). In other words, the lungs are the primary organs that get rid of fat and the kidneys excrete the water. There is a bit of extra energy in this chemical reaction as well, which dissipates through the skin and through exhaled air.

What did health professionals think where the fat would go?

The health professionals were doctors, dieticians and personal trainers. About 65% of them thought fat would evaporate into energy/heat. About 10% thought fat would end up in the feces. 5% thought fat would turn into muscle. Another 5% thought fat would turn into sweat or urine. 8% were correct that fat would become CO2 and H2O. 7% said they did not know.

The chemistry of fat deposits and metabolizing fat

The body deposited triglycerides from the liver metabolism of sugar and fatty acids into fat cells and stored them as oleate (C18H34O2), palmitate (C16H32O2), and linoleate (C18H32O2). Part of this are many chemical reactions, including a number of enzymes. These fatty acids form esters and turn into gigantic molecules with this chemical formula: C55H104O6. The BMJ paper further says that an overall chemical description of metabolized fat would look like this:

C55H104O6+78O2→55CO2+52H2O+energy. In plain English it means that 1 molecule of fat ester (from fat storage) is metabolized together with 78 molecules of oxygen. This results in 55 molecules of carbon dioxide, 52 molecules of water and energy.

Fat turns into carbon dioxide and water

Based on this chemical reaction a calculation of the breakdown of fat into carbon dioxide and water was possible. The surprising result is that 84% of fat becomes carbon dioxide and only 16% of fat becomes water. We exhale the carbon dioxide from our lungs and it is mostly the kidneys that excrete the water. People who lose weight are aware that they have to urinate more often. But they do not notice that they get rid of a lot of carbon dioxide, as this is a subtle process.

Some observations from the fasting mimicking diet

The fasting mimicking diet (FMD) was at the center of the most recent anti-aging conference in Las Vegas I attended. This was the 25th Annual World Congress on Anti-Aging Medicine in Las Vegas, Dec. 14-16, 2017. Late in December 2017 I started 5 days of FMD and have just completed my 4th round of it (FMD is done 5 days out of each month). My main interest in doing this is to prevent heart attacks and strokes and I like the idea of stimulating telomeres for anti-aging and increasing stem cell production. See more details under this link.

Personal experience of fasting mimicking diet

I keep meticulous records of my body measurements using daily body composition scales, which I record in a booklet. Between March 23, 2018 and March 28 I lost 1.5 kg from 64.8 kg to 63.3 kg. Fat composition was reduced from 14.1% to 12.2%. Visceral fat was reduced from 6% to 5%. My muscle percentage rose from 38.1% to 39.1%. The basic metabolic rate was 1471 Calories on March 23 and went down to 1449 Calories on March 28. My body mass index went from 22.0 to 21.5.

I definitely noticed the frequent urination, something I had noticed in the past in 2001 when I lost 50 pounds over 3 months. Of course it is understandable when you reduce your daily calorie intake to 600 Calories per day that you will lose this amount of weight. People have different metabolisms. It may be that you won’t lose as much as I did.

What causes mainly weight loss?

There are many people who think that extra exercise would help you lose weight. But a publication has established that only about 8% of weight loss is due to exercising. 92% of weight loss is due to dieting.

Regular exercise is important for conditioning of your lungs, heart, muscles and joints. But to keep things in balance a reasonable diet, like a Mediterranean diet, should also be part of the regimen.

Sugar overconsumption

The obesity wave in the US started to take off between 1976 and 1980. 40 years later it is still rising. It is interesting to note that both wheat flour and sugar consumption in the US were increasing parallel to the rising obesity figures. In the 70’s the old-fashioned wheat has changed into the force hybridized Clearfield wheat, which is now 100% of the commercially available wheat. Clearfield wheat contains 7-fold higher gluten amounts than the old-fashioned wheat that your grandparents consumed. Gluten stimulates your appetite, so you crave more wheat and you crave more sugar. This becomes a vicious cycle.

Excess calories are stored as fat

The liver metabolizes sugar from regular food and from processed food into triglycerides and LDL cholesterol (the bad cholesterol that plugs up arteries). As I mentioned above, the body stores any excess triglycerides as fat and deposits the excess into fatty cells. You see from this that essentially sugar and wheat end up as fat deposits. I suggest you change your food intake into eating sensible food with fewer calories. Start by eliminating most of your sugar, wheat and processed food intake. This will help you to melt fat away as I showed with an example of my 5 day FMD.

Where Does Fat Go With Weight loss?

Where Does Fat Go With Weight loss?

Conclusion

I reviewed facts about the chemistry of melting fat away. The question is where does fat go with weight loss? In the process of weight loss fat breaks down into carbon dioxide and water. I also documented how you can lose fat in just 5 days (1.1 kilogram) on a 600-calorie diet and reduce the body mass index from 22.0 to 21.5.

Most people do not recognize the importance of watching their diet to achieve weight loss. 92% of weight loss occurs as a result of dieting. Wheat and sugar consumption have a direct connection to the obesity wave that started between 1976 and 1980. I have cut out all wheat, all sugar and all processed food in 2001. This allowed me to lose 50 pounds then and my body mass index today is 21.5. It can be done, even if you are 73 years old.